Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site by Banach, Bailey B, Pletnev, Sergei, Olia, Adam S, Xu, Kai, Zhang, Baoshan, Rawi, Reda, Bylund, Tatsiana, Doria-Rose, Nicole A, Nguyen, Thuy Duong, Fahad, Ahmed S, Lee, Myungjin, Lin, Bob C, Liu, Tracy, Louder, Mark K, Madan, Bharat, McKee, Krisha, O’Dell, Sijy, Sastry, Mallika, Schön, Arne, Bui, Natalie, Shen, Chen-Hsiang, Wolfe, Jacy R, Chuang, Gwo-Yu, Mascola, John R, Kwong, Peter D, DeKosky, Brandon J

“…Here we evolve the FP-targeting antibody VRC34.01 in vitro to enhance FP-neutralization using site saturation mutagenesis and yeast display. Successive rounds of directed evolution by iterative selection of antibodies for binding to resistant HIV-1 strains establish a variant, VRC34.01_mm28, as a best-in-class antibody with 10-fold enhanced potency compared to the template antibody and ~80% breadth on a cross-clade 208-strain neutralization panel. …”
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Crystal structure of the FK506 binding domain of plasmodium falciparum FKBP35 in complex with FK506 by Kotaka, Masayo, Ye, Hong, Alag, Reema, Hu, Guangan, Bozdech, Zbynek, Preiser, Peter Rainer, Yoon, Ho Sup, Lescar, Julien

“…It binds to a α/β protein module of approximately 120 amino acids known as the FK506 binding domain (FKBD), which is found in various organisms, including human, yeast, and Plasmodium falciparum (PfFKBD). Antiparasitic effects of FK506 and its analogues devoid of immunosuppressive activities have been demonstrated. …”
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Finding transcription factor binding motifs for coregulated genes by combining sequence overrepresentation with cross-species conservation by Jia, Hui., Li, Jinming.

“…Compared with the prevailing motif finding software, our method has some advantages in finding transcriptional factor binding motifs for potential coregulated genes if the gene upstream sequences of multiple closely related species are available. Although we used yeast genomes to assess our method in this study, it might also be applied to other organisms if suitable related species are available and the upstream sequences of coregulated genes can be obtained for the multiple closely related species.…”
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Niemann-Pick type c disease: pathogenesis and therapy by Colaco, A

“…To gain further insight into the function of NPC1 and proteins it interacts with we used the yeast orthologue, Ncr1p. I recreated the Δncr1 mutant and characterized the mutant using an array of systematic screens to identify different processes and pathways that may play a role in NPC pathogenesis. …”

Isolation of Bifidobacteria infantis and its antagonistic activity against ETEC 0157 and Salmonella typhimurium S-285 in weaning foods by Mohd Yusof, Rokiah, Haque, Formuzul, Ismail, Maznah, Hassan, Zaiton

“…Trypticase phytone peptone yeast extract agar (TPY) was used as a selective media for the isolation. …”

Structural investigation, computational analysis, and theoretical cryoprotectant approach of antifreeze protein type IV mutants by Eskandari, Azadeh, Leow, Thean Chor, Abdul Rahman, Mohd Basyaruddin, Oslan, Siti Nurbaya

“…In this in silico study, the helical peptide afp1m from an Antarctic yeast AFP was modeled into a sculpin AFPIV, to replace each of its four α-helices in turn, using various computational tools. …”

Microbial lipid production from food waste saccharified liquid and the effects of compositions by Ma, Xiaoyu, Gao, Zhen, Gao, Ming, Ma, Yingqun, Ma, Hongzhi, Zhang, Min, Liu, Yu, Wang, Qunhui

“…The residues of food waste after removing waste cooking oils could be converted to microbial lipid by oleaginous yeasts and microbial lipid could be used as a raw material of biodiesel with waste cooking oils. …”
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R-loopDB: a database for R-loop forming sequences (RLFS) and R-loops by Jenjaroenpun, Piroon, Wongsurawat, Thidathip, Sutheeworapong, Sawannee, Kuznetsov, Vladimir A.

“…It includes genome-scale prediction of RLFSs for humans, six other animals and yeast. Using the extended quantitative model of RLFSs (QmRLFS), we significantly increased the number of RLFSs predicted in the human genes and identified RLFSs in other organism genomes. …”
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Expression of recombinant geobacillus SP a-amylase in pichia pastoris GS 115 by Gandhi, Sivasangkary

“…Pichia pastoris is a currently well established methanol utilizing yeast expression system. The aim of the studies was to produce a recombinant Geobacillus sp. α-amylase SR74 in P. pastoris GS115 and characterize the biochemical properties of the purified recombinant α-amylase. …”
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Design for assembly and application using Hitachi assemblability evaluation method by Mohd Naim, Zakaria

“…From this project, the component of mini radio have been reduce from 21 part to 16 part by combining some component that made from same material and not necessary component become one part. …”
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30 Essential Skills for the Qualitative Researcher / by Creswell, John W., author 401571, Creswell Báez, Johanna, author 655108

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Electrochemistry of modified graphene and carbon nanomaterials by Poh, Hwee Ling

“…The study is divided into three parts: a) Part 1: Influence of heteroatom functionalization on the properties of graphene, b) Part 2: Influence of synthesis methods/conditions on the properties of graphene and c) Part 3: Influence of structural differences on the properties of nanocarbons. …”
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Cellular studies on the role of OGFOD1, a 2-oxoglutarate-dependent dioxygenase by Attwood, M

“…<p>2-Oxoglutarate (2-OG) and iron (Fe²⁺) dependent Oxygenase Domain containing protein 1 (OGFOD1) is an evolutionarily conserved prolyl hydroxylase enzyme in mammals, invertebrates (Sud1 in D. melanogaster) and yeast (TPA1 in S. cerevisiae and Ofd1 in S. pombe). …”

Medium formulation and optimisation of fermentation condition enhancing g-aminobutyric Acid (GABA) biosynthesis by Lactiplantibacillus plantarum B7 by Pannerchelvan, Sangkaran, Faizal Wong, Fadzlie Wong, Wasoh, Helmi, Mohamed, Mohd Shamzi, Mohamad, Rosfarizan, Halim, Murni

“…A nutrient-rich medium was developed through single-parameter optimisation, comprising 1%, 2.5% and 0.0002% of glucose, yeast extract and each trace element (CaCO3, KI, and Tween 80) respectively. …”
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RES.12-001 Topics in Fluid Dynamics, Fall 2023 by Price, James F.

“…The collection includes the following three essays: Essay 1: Lagrangian and Eulerian Representations of Fluid Flow (revised and expanded in 2024) Part 1: Kinematics and the Equations of Motion Part 2: Advection of Parcels and Fields Essay 2: Dimensional Analysis of Models and Data Sets: Similarity Solutions and Scaling Analysis Essay 3: A Coriolis Tutorial (revised and expanded in 2023) Part 1: The Coriolis Force, Inertial and Geostrophic Motion Part 2: A Rotating Shallow Water Model and Geostrophic Adjustment Part 3: Beta Effects and Western Propagation Part 4: Wind-Driven Ocean Circulation and the Sverdrup Relation Part 5: On the Seasonally-Varying Circulation of the Arabian Sea The goal of this resource is to help each student master the concepts and mathematical tools that make up the foundation of classical and geophysical fluid dynamics. …”
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Secure wirelessly powered networks at the physical layer: challenges, countermeasures, and road ahead by Lu, Xiao, Nguyen Cong Luong, Dinh Thai Hoang, Niyato, Dusit, Xiao, Yong, Wang, Ping

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Attention-aware resource allocation and QoE analysis for metaverse xURLLC services by Du, Hongyang, Liu, Jiazhen, Niyato, Dusit, Kang, Jiawen, Xiong, Zehui, Zhang, Junshan, Kim, Dong In

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Wireless and Mobile Networking / by Hassan, Mahbub, author 346055

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QUALITATIVE RESEARCH in BUSINESS AND MANAGEMENT / by Myers, Michael D. (Michael David), 1954-, author 210024

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Adaptive macro spatial modulation for mmWave dense networks by Luo, Sheng, Che, Yue Ling, Wu, Kaishun, Teh, Kah Chan

“…In the proposed scheme, a user equipment (UE) adaptively establishes communication links with multiple small base stations (SBSs) and switches its beam direction between these SBSs according to part of its transmitting information. We first model the optimal signal transmission scheme that minimizes system symbol-error rate (SER) as an optimization problem and propose an iterative method with relative high computational complexity to solve it. …”
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