Rationalisation of antifungal properties of α-helical pore-forming peptide, mastoparan B by Lim, Edward Jianyang, Goh, Eunice Tze Leng, Tram, Nhan Dai Thien, Periayah, Mercy Halleluyah, Ee, Rachel Pui Lai, Barkham, Timothy Mark Sebastian, Poh, Zhi Sheng, Verma, Navin Kumar, Lakshminarayanan, Rajamani

“…Among the four peptides, mastoparan B (MB) displayed potent antifungal activity, whereas cecropin A was the least potent. We show that MB susceptibility of phylogenetically distant non-candida albicans can vary and be described by different intrinsic physicochemical parameters of pore-forming α-helical peptides. …”
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Molecular recognition in protein-DNA assemblies by Davey, Curt Alexander

“…Extensive adduct formation observed at the centre of the NCP suggests that this region of the nucleosome, known to be least accessible to protein factors, may provide a favorable target for the design of improved platinum anticancer drugs.In addition to platinum drug site selectivity studies, we engaged in biophysical and biochemical studies revealing functional aspects of chromatin-drug interactions that are shedding light on new possibilities for anticancer agent development. …”
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Evaluation of the safety and immunogenicity of different COVID-19 vaccine combinations in healthy individuals: study protocol for a randomized, subject-blinded, controlled phase 3... by Poh, Xuan Ying, Lee, I. Russel, Lim, Clarissa, Teo, Jefanie, Rao, Suma, Chia, Po Ying, Ong, Sean W. X., Lee, Tau Hong, Lin, Ray J. H., Ng, Lisa F. P., Ren, Ee Chee, Lin, Raymond T. P., Wang, Lin-Fa, Renia, Laurent, Lye, David C., Young, Barnaby Edward

“…More than 90% of the Singapore population has received at least one dose of a COVID-19 vaccine as of December 2021. …”
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Joint client-and-sample selection for federated learning via bi-level optimization by Li, Anran, Wang, Guangjing, Hu, Ming, Sun, Jianfei, Zhang, Lan, Tuan, Luu Anh, Yu, Han

“…Extensive experiments comparison against eight state-of-the-art baselines on six real-world datasets in the presence of data noise and heterogeneity shows that FedMW-CSS achieves up to 28.5% higher test accuracy, while saving communication and computation costs by at least 49.3% and 1.2%, respectively.…”
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High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo magnetic particle imaging by Tay, Rong En, Lokamitra, P., Pang, Shun Toll, Low, Kay En, Tay, Hui Chien, Ho, Charmaine Min, Malleret, Benoit, Rötzschke, Olaf, Olivo, Malini, Tay, Zhi Wei

“…Results: Labelling efficiency was improved more than 10-fold over prior studies enabling longer-term tracking for at least two weeks in vivo of the labelled immune cells and their biodistribution relative to the tumour. …”
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Synthesis and characterization of reduced graphene oxide-based composites by Wu, Shixin

“…In addition, the Fe3O4-Pt/rGO composite can catalyze the reduction of methylene blue and be recycled within 1 min by applying an external magnetic field for at least 16 times.…”
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Electric-field control of magnetism in multiferroic composites by Ding, Hui

“…Multiferroic materials have at least two of the ferroic properties, namely ferroelectricity, ferro (anitferro) magnetism and ferroelasticity.The term usually refers to materials that possess both ferroelectric and magnetic orders. …”
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Selective lighting up of epiberberine alkaloid fluorescence by fluorophore-switching aptamer and stoichiometric targeting of human telomeric DNA G-quadruplex multimer by Zhang, Lihua, Liu, Hua, Shao, Yong, Lin, Clement, Jia, Huan, Chen, Gang, Yang, Danzhou, Wang, Ying

“…The binding affinity of EPI to TA[Q] (Kd = 37 nM) is at least 20 times tighter than those of the other alkaloids. …”
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Upper mantle rheology from GRACE and GPS postseismic deformation after the 2004 Sumatra-Andaman earthquake by Banerjee, Paramesh, Panet, I., Mikhailov, V., Diament, M., Grijalva, K., Pollitz, Fred F.

“…Mantle rheology is one of the essential, yet least understood, material properties of our planet, controlling the dynamic processes inside the Earth's mantle and the Earth's response to various forces. …”
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Role of the collagen receptor DDR1 in epithelial morphogenesis and polarisation by Søgaard, P

“…</p> <p>Overall, this study suggests that DDR1 signalling contributes to epithelial polarisation and morphogenesis in a manner involving regulation of cytoskeletal organisation, at least partly through regulation of ROCK activity.…”

Consensus on current management of endometriosis by Johnson, NP, Hummelshoj, L, World Endometriosis Society Montpellier Consortium

“…Several guidelines have been developed by a number of national and international bodies, yet areas of controversy and uncertainty remain, not least due to a paucity of firm evidence. </p> <p><strong>Study design, size, duration:</strong> A consensus meeting, in conjunction with a pre- and post-meeting process, was undertaken. …”

Internet tool to support self-assessment and self-swabbing of sore throat: development and feasibility study by Lown, M, Smith, KA, Muller, I, Woods, C, Maund, E, Rogers, K, Becque, T, Hayward, G, Moore, M, Little, P, Glogowska, M, Hay, A, Stuart, B, Mantzourani, E, Wilcox, CR, Thompson, N, Francis, NA

“…A web-based tool that helps people assess their sore throat, through the use of clinical prediction rules, taking throat swabs or saliva samples, and taking throat photographs, has the potential to improve self-management and help identify those who are the most and least likely to benefit from antibiotics. <br><strong> Objective:<br></strong> We aimed to develop a web-based tool to help patients and parents or carers self-assess sore throat symptoms and take throat photographs, swabs, and saliva samples for diagnostic testing. …”

Antihyperlipidemic and hepatoprotective effect of Zingiber cassumunar Rhizome extract in high-fat diet-induced hyperlipidemic rats: the role of antioxidant activity by Mahfudh, Nurkhasanah, Sulistyani, Nanik, Sari, Novita Sari, Sari, Indah Puspita, Dedi, Adrian, Othman, Fezah, Zakaria, Zainul Amiruddin

“…Data of the study were presented as mean ± SD and analyzed by using one way analysis of variance (ANOVA) followed by Least Significant Difference (LSD) test for multiple comparisons. …”
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Effects of carbon to nitrogen ratio and organic loading rate on biogas methane production from anaerobic digestion of food waste by Tanimu, Musa Idris

“…The feedstock with C/N=30 had the least foaming tendency with foaming volume of 10% at OLR of 7.5 g VS/Ld.…”
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离散、家国、女性 ： 韩素音的中国性论述 = Diaspora, home, feminism : the Chinese-ness in Han Suyin’s works by 梁依婷 Neo, Yi Ting

“…Therefore, she always felt socially excluded but yet held strong desires to help connect the East and the West. Despite experiencing transnational diaspora, Han Suyin devoted her entire life into crossing the boundaries between different nations, cultures, race and gender, and upholding of the Chinese culture. …”
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Priorities to inform research on marine plastic pollution in Southeast Asia by Omeyer, Lucy C. M., Duncan, Emily M., Aiemsomboon, Kornrawee, Beaumont, Nicola, Bureekul, Sujaree, Cao, Bin, Carrasco, Luis R., Chavanich, Suchana, Clark, James R., Cordova, Muhammad R., Couceiro, Fay, Cragg, Simon M., Dickson, Neil, Failler, Pierre, Ferraro, Gianluca, Fletcher, Stephen, Fong, Jenny, Ford, Alex T., Gutierrez, Tony, Shahul Hamid, Fauziah, Hiddink, Jan G., Hoa, Pham T., Holland, Sophie I., Jones, Lowenna, Jones, Nia H., Koldewey, Heather, Lauro, Federico M., Lee, Charlotte, Lewis, Matt, Marks, Danny, Matallana-Surget, Sabine, Mayorga-Adame, Claudia G., McGeehan, John, Messer, Lauren F., Michie, Laura, Miller, Michelle A., Mohamad, Zeeda F., Nor, Nur Hazimah Mohamed, Müller, Moritz, Neill, Simon P., Nelms, Sarah E., Onda, Deo Florence L., Ong, Joyce J. L., Pariatamby, Agamuthu, Phang, Sui C., Quilliam, Richard, Robins, Peter E., Salta, Maria, Sartimbul, Aida, Shakuto, Shiori, Skov, Martin W., Taboada, Evelyn B., Todd, Peter A., Toh, Tai Chong, Valiyaveettil, Suresh, Viyakarn, Voranop, Wonnapinij, Passorn, Wood, Louisa E., Yong, Clara L. X., Godley, Brendan J.

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Characterization of Newcastle disease virus (NDV) isolated from NDV vaccinated broiler farms and investigation of vaccine efficacy against challenge with Velogenic genotype VII NDV by Shahrestani, Kiarash Roohani

“…However, since 1990s genotype VII NDV is the predominant velogenic NDV circulating in South-East Asia causing outbreaks even in well vaccinated flocks. …”
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Precipitation trend analysis for The Langat River Basin, Selangor, Malaysia by Palizdan, Narges

“…The results of the seasonal precipitation trend analysis showed that most of the stations, during the North East Monsoon (NEM) and Inter Monsoon 1 (INT1) seasons, and half of the stations in South West Monsoon (SWM) season, experienced insignificant positive trends. …”
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Target Design and Optimizations for Spent Fuel Transmutation by Tukharyan, Grigor

“…There are six long-lived fission products (LLFPs) identified in nuclear spent fuel, which account for at least 99% of the long-term radiotoxicity once actinide recycling is completed. …”
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Structural molecular modeling of bacterial integral membrane protein enzymes and their AlphaFold2 predicted water-soluble QTY variants by Sajeev-Sheeja, Akash, Zhang, Shuguang

“…We superposed the structures of native beta-barrel integral membrane enzymes with their AlphaFold2-predicted QTY variant structures that showed remarkable similarity despite the replacement of at least 22.95% amino acids in transmembrane regions, the superposed structures displayed notable structural similarity, indicated by RMSD values ranging from 0.181 Å to 0.286 Å. …”
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