Investigating the role of astrocytes in Parkinson's disease pathogenesis in GBA- N370S iPSC-derived neural cultures by Ibarra Aizpurua, N

“…Moreover, even if <em>CYP27B1</em> and <em>VDR</em> expression and nuclear translocation were elevated in reactive iASTROs, vitamin D supplementation in iDAn did not result in changes in cell viability.</p> <p>Lastly, to investigate if iASTROs treated with inflammatory cytokines presented neurotoxic or neuroprotective characteristics, experiments in iDAn-iASTRO co-cultures were conducted. …”

Color and flavor development of roasted jackfruit (Artocarpus hetrophyllus L.) seeds by Azeez, Shakirah Omotoke

“…The aim of this research therefore was to investigate the flavor and color development in JFS during roasting, through; chemical analysis, sugar profiling and amino acid profiling of both raw and roasted JFS; color development analysis using response surface methodology (RSM); effect of roasting condition on the structural changes of the starch granules using scanning electron microscopy (SEM) and Fourier Transform Infrared spectroscopy (FTIR); and lastly flavor development analysis using gas chromatography-olfactometry (GC-O) and gas chromatography-mass spectrometry (GC-MS) coupled with aroma extract dilution analysis (AEDA) for the identification of key odorants. …”
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Investigations into femtosecond laser hybrid manufacturing for 3D power sources by Tham, Nicholas Cheng Yang

“…Together, these results demonstrate LPG’s usefulness for high performance, self-powered graphene paper electronics. Lastly, the bulk structuring of optically transparent materials through fsLIL for 3D MBs and MSCs is studied. …”
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Essays on blood supply management by Senga, Juan Ramon Liboro

“…We also observe that the dynamic donation rate strategy results in lower fill-rates during disasters when the fill-rate is low despite being able to meet donation targets, and that multiple waves with short lead times exacerbate this effect. Lastly, we introduce three ethically complex interventions: (1) demand deferral, (2) rationing of blood, and (3) tapping non-traditional donor pools and show that these can be implemented from both the analytical and simulation models. …”
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Evaluating the socio-environmental impacts of monoculture cashew expansion in the Northern Western Ghats, India by Anushka Rege

“…The area under cashew cultivation as of 2020 in the Sawantwadi-Dodamarg landscape was 53,350 ha. Lastly, I compared bird diversity across cashew plantations, privately owned forests and government-controlled forests, using both acoustic methods and point count methods. …”
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Conflict-free urban air mobility planning with an airspace-resource-centric approach by Dai, Wei

“…The model will be used in the evaluation of trajectory planning from the perspective of power consumption. Lastly, in the final stage, we present a multi-objective 4D trajectory optimization model using the ARC concept. …”
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会话分析研究 ：“就” 作为回应开头单位的互动会话功能 = Conversation Analysis : “jiu” as a turn-initial object of a response in Mandarin conversation by 林美琦 Lim, Maggie Meiqi

“…These includes: 1) respondent can use “jiu” as a turn-initial object of a response to express rejection towards the utterance in the prior turn; 2) respondent can use “jiu” as a turn-initial object of a response to express resistance towards the implied agenda of an utterance in the prior turn; 3) respondent can use “jiu” as a turn-initial object of a response to index the prior turn as self-evident. Lastly, I will also make use of Face Theory from Brown and Levinson to discuss the deployment of “jiu” as a turn-initial object of a response and what it could reflect about the social interaction between people.…”
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Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Previously, it had been observed that a single high-dose treatment with the iminosugar MON-DNJ led to long-lasting antiviral effects in lethal dengue mouse models via alpha-glucosidase I inhibition. …”

The iHealth-T2D study, prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes: study protocol for a randomised controlled trial by Kasturiratne, Anuradhani, Khawaja, Khadija I., Ahmad, Sajjad, Siddiqui, Samreen, Shahzad, Khurram, Athauda, Lathika K., Jayawardena, Ranil, Mahmood, Sara, Muilwijk, Mirthe, Batool, Tayyaba, Burney, Saira, Glover, Matthew, Palaniswamy, Saranya, Bamunuarachchi, Vodathi, Panda, Manju, Madawanarachchi, Suren, Rai, Baldeesh, Sattar, Iqra, Silva, Wnurinham, Waghdhare, Swati, Jarvelin, Marjo-Riitta, Rannan-Eliya, Ravindra P., Gage, Heather M., van Valkengoed, Irene G. M., Valabhji, Jonathan, Frost, Gary S., Loh, Marie, Wickremasinghe, Ananda R., Kooner, Jaspal S., Katulanda, Prasad, Jha, Sujeet, Chambers, John C.

“…Secondary endpoints at 1 and 3 years are the following: (i) physical measures: waist circumference, weight and blood pressure; (ii) lifestyle measures: smoking status, alcohol intake, physical activity and dietary intake; (iii) biochemical measures: fasting glucose, insulin and lipids (total and HDL cholesterol, triglycerides); and (iv) treatment compliance. …”
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Exploring the Dynamics of Canine-Assisted Interactions: A Wearable Approach to Understanding Interspecies Well-Being by Holder, Timothy R. N., Nichols, Colt, Summers, Emily, Roberts, David L., Bozkurt, Alper

“…We also present three new representations of the internal and overall dynamics of CAIs for adoption by the broader field. Lastly, this paper discusses ongoing options for further dyadic analysis, interspecies emotion prediction, integration of contextually relevant environmental data, and standardization of human–animal interaction equipment and analytical approaches. …”
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AI techniques in CFD: leveraging physical priors with deep learning to improve on numerical solvers by Loh, Jessica Sher En

“…Additionally, it extends the use of residual training to improve flow field prediction for a GNN scenario with immersed object, when low resolution data is available. Lastly, the third part aims to enhance flow predictions around complex geometries, which may often be deconstructed into multiple, simple bodies, by leveraging existing data on these single geometry flow fields. …”
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Design and growth of high-power gallium nitride light-emitting diodes by Zhang, Zihui

“…We have also suggested InGaN/GaN LED devices with the electron overflow reduction through incorporating n-type InGaN layer and n-type AlGaN layer into the n-GaN layer, respectively, accompanied with which a mean-free-path model has been proposed and demonstrated to explain the mechanism of the electron overflow reduction through decreasing the electron mean free path. Lastly, as it has been mentioned previously, the low p-type conductivity in the InGaN/GaN LEDs has substantially limited the LED performance. …”
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Methods of growth and transfer of carbon nanotubes onto substrates for advanced electrical and electronic applications by Ng, Zhi Kai

“…These observations indicate the potential to achieve a lightweight, conductive, high surface area composite electrodes. Lastly, ongoing research, insights, research directions and potential applications are elaborated. …”
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Towards electrically injected colloidal semiconductor lasers by Thung, Yi Tian

“…These breakthroughs underscore the ability of colloidal NPLs to be seamlessly integrated into practical lasing applications, overcoming previous limitations with epitaxially grown laser solid microcavities. Lastly, pursuing electrically injected colloidal NPLs lasers, I sandwiched core/hybrid-shell CdSe/CdS@Cd1−xZnxS NPLs as a gain material between two double Bragg reflectors (DBRs) to fabricate a vertical cavity surface-emitting lasers (VCSELs). …”
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The effects of atmosphere-ocean-wave coupling during tropical cyclone by Garg, Nikhil

“…The coupling modifies the low-level boundary layer structure and the physical properties of near surface flow in TCs, which subsequently affects the physical mechanisms such as convective organisation. Lastly, it was shown that at the air-sea interface, there are a number of physical processes that can affect the TC. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Brauer, M, Roth, GA, Aravkin, AY, Bandyopadhyay, S, Bennett, DA, Browne, AJ, Graham, SM, Rodriguez, JAB, Runghien, T, Sartorius, B

“…<p><b>Findings</b></p> Among the specific risk factors analysed for this study, particulate matter air pollution was the leading contributor to the global disease burden in 2021, contributing 8·0% (95% UI 6·7–9·4) of total DALYs, followed by high systolic blood pressure (SBP; 7·8% [6·4–9·2]), smoking (5·7% [4·7–6·8]), low birthweight and short gestation (5·6% [4·8–6·3]), and high fasting plasma glucose (FPG; 5·4% [4·8–6·0]). For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. …”

Tonsillectomy or adenotonsillectomy versus non‐surgical treatment for chronic/recurrent acute tonsillitis by Burton, MJ, Glasziou, PP, Chong, LY, Venekamp, RP

“…The size of the effect is very modest, but there may be a benefit to knowing the precise timing of one episode of pain lasting several days ‐ it occurs immediately after surgery as a direct consequence of the procedure. …”

Health monitoring, lifetimes estimation, and thermal management of IGBT-based power converters by Mohamed Halick Mohamed Sathik

“…This thesis proposes and discusses an online measurement technique for health monitoring of power modules in power converter systems. Lastly, a three-phase inverter system is developed for experiments to verify the proposed method in real time operating conditions. …”
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Preparation of low-dimensional materials for plasmonic bio-sensing by Das, Chandreyee Manas

“…With this our motive was to show how TMDC based functionalization-free SPR sensors can also be realized in the domain of commercial sensing platforms. Lastly, we performed some optical experiments (GH shift sensitivity) to compare the sensitivities of pure Au and graphene coated Au chips. …”
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