-
1
Development of youth tennis players: A study based on the ranking history of top ATP/WTA players worldwide and China.
Published 2023-01-01“…<h4>Background</h4>The top 100 ATP/WTA ranking points are a crucial indicator of entry into the high-level world of tennis players, and the number of players from a nation in this ranking reflects the overall level of their tennis. …”
Get full text
Article -
2
Downregulation by CNNM2 of ATP5MD expression in the 10q24.32 schizophrenia-associated locus involved in impaired ATP production and neurodevelopment
Published 2021-05-01“…Here, we employed region-based multi-marker analysis of genomic annotation (MAGMA) to identify additional risk loci containing variants with large OR value from Psychiatry Genomics Consortium (PGC2) schizophrenia GWAS data and then employed summary-data-based mendelian randomization (SMR) to prioritize schizophrenia susceptibility genes. The top-ranked susceptibility gene ATP5MD, encoding an ATP synthase membrane subunit, is observed to be downregulated in schizophrenia by the risk allele of CNNM2-rs1926032 in the schizophrenia-associated 10q24.32 locus. …”
Get full text
Article -
3
-
4
ATP induces folding of ALS-causing C71G-hPFN1 and nascent hSOD1
Published 2023-09-01“…The inducing capacity ranks as: ATP = ATPP = PPP > ADP = AMP−PNP = AMP−PCP = PP, while AMP, adenosine, P, and NaCl show no conversion. …”
Get full text
Article -
5
-
6
Tereticornate A suppresses RANKL-induced osteoclastogenesis via the downregulation of c-Src and TRAF6 and the inhibition of RANK signaling pathways
Published 2022-07-01“…Mechanistically, TA downregulated the expression of c-Src and TRAF6, and also suppressed the RANKL-stimulated canonical RANK signaling pathways, including AKT, MAPK (p38, JNK, and ERK), and NF-κB; ultimately, downregulating the expression of NFATc1 and c-Fos, the key transcriptional factors required for the expression of genes (e.g., TRAP, cathepsin K, β-Integrin, MMP-9, ATP6V0D2, and DC-STAMP) that govern osteoclastogenesis. …”
Get full text
Article -
7
Automated mass action model space generation and analysis methods for two-reactant combinatorially complex equilibriums: An analysis of ATP-induced ribonucleotide reductase R1 hexa...
Published 2009-12-01“…R1 has 5 possible catalytic site states (empty or filled with 1 of 4 NDPs), 5 possible <it>s</it>-site states (empty or filled with ATP, dATP, dTTP or dGTP), 3 possible <it>a</it>-site states (empty or filled with ATP or dATP), perhaps two possible <it>h</it>-site states (empty or filled with ATP), and all of this is folded into an R1 monomer-dimer-tetramer-hexamer equilibrium where R1 j-mers can be bound by variable numbers of R2 or p53R2 dimers. …”
Get full text
Article -
8
The Relation of Haplotype ATP-binding Cassette B1 and Glutathione S-transferase P1 A313G Genes with Hematological Toxicity in Indonesian Breast Cancer Patients Receiving Chemothera...
Published 2022-03-01“…We investigate the incidence of hematological toxicities and their relation to the haplotype ATP-binding cassette B1 (ABCB1) which were polymorphisms of C1236T, C3435T, G2677T, and glutathione S-transferase P1 (GSTP1) A313G genes in Indonesian breast cancer patients who received anthracycline during chemotherapy. …”
Get full text
Article -
9
Zoledronic Acid as a Novel Dual Blocker of KIR6.1/2-SUR2 Subunits of ATP-Sensitive K<sup>+</sup> Channels: Role in the Adverse Drug Reactions
Published 2021-08-01“…Docking investigation revealed that the drug binds to the ADP/ATP sites on KIR6.1/2 and SUR2A/B and on the sulfonylureas site showing low binding energy <6 Kcal/mol for the KIR6.1/2-SUR2 subunits vs. the <4 Kcal/mol for the KIR6.2-SUR1. …”
Get full text
Article -
10
-
11
A comparison of adenosine triphosphate with other metrics of microbial biomass in a gradient from the North Atlantic to the Chesapeake Bay
Published 2024-01-01“…A compilation of prior research data from a wide range of marine habitats demonstrated that ATP values can be ranked according to broad trophic gradients, from the deep sea to eutrophic inland waters. …”
Get full text
Article -
12
-
13
Involvement of Potassium Channel Signalling in Migraine Pathophysiology
Published 2023-03-01“…Emerging evidence implicates potassium channels, predominantly ATP-sensitive potassium (K<sub>ATP</sub>) channels and large (big) calcium-sensitive potassium (BK<sub>Ca</sub>) channels in migraine attack initiation. …”
Get full text
Article -
14
-
15
Validation of Reference Genes for Real-Time Quantitative PCR (qPCR) Analysis of Avibacterium paragallinarum.
Published 2016-01-01“…Data analyzed by overall rankings showed that in exponential and stationary phase of serovar A, the most stable reference genes were gyrA and atpD respectively; in exponential and stationary phase of serovar B, the most stable reference genes were atpD and recN respectively; in exponential and stationary phase of serovar C, the most stable reference genes were rpoB and recN respectively. …”
Get full text
Article -
16
Talent identification among elite Czech male junior tennis players (U12) according to their future tennis performance and birthdate
Published 2023-05-01“…The participants were players U12 who were later among top 1000 in the ATP Singles Rankings (SR). The research data was obtained during regular testing of the Czech Tennis Association (1998–2019). …”
Get full text
Article -
17
Natural Anthraquinones as Promising MAPK3 Inhibitors for Complementary Cancer Therapy
Published 2023-01-01“…Using AutoDock 4.0 software, the binding affinity of 21 AQs to the receptor’s active site was evaluated. AQs were ranked based on their ΔGbinding values to the receptor’s active site, with the highest rankings receiving the most favorable scores. …”
Get full text
Article -
18
A systems biology approach to pathogenesis of gastric cancer: gene network modeling and pathway analysis
Published 2023-07-01“…Abstract Background Gastric cancer (GC) ranks among the most common malignancies worldwide. …”
Get full text
Article -
19
Exploiting receptor flexibility to improve the accuracy of structure-based virtual screening
Published 2017“…The data obtained suggest that A22 may not function as an inhibitor of ATP hydrolysis. Analysis of the dynamics of water molecules in the MreB active site reveals that in the presence of A22 water molecules are able to occupy positions suitable for ATP hydrolysis. …”
Get full text
Thesis -
20
Prediction of Metabolic Syndrome in a Mexican Population Applying Machine Learning Algorithms
Published 2020-04-01“…In this work, we used the ATP III criteria as the framework with the purpose to rank the health parameters (clinical and anthropometric measurements, lifestyle data, and blood tests) from a data set of 2942 participants of Mexico City Tlalpan 2020 cohort, applying machine learning algorithms. …”
Get full text
Article