Digital health initiatives and the policy context in European integrated health systems by Micol Tedeschi, Mariana Dates, Niamh Lennox-Chhugani

“…As part of a study commissioned by Chafea and DG SANTE, Optimity Advisors has conducted an extensive review and mapping of ICI across Europe, to assess the level of penetration and adoption of ICI in the 30 countries and evaluate the level of maturity of several healthcare systems. …”
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‘It doesn’t happen how you think, it is very complex!’ Reconciling stakeholder priorities, evidence, and processes for zoonoses prioritisation in India by Festus A. Asaaga, Aditi Sriram, Mudassar M. Chanda, Subhash L. Hoti, Juliette C. Young, Bethan V. Purse

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Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials by Ruman Rahman, Miroslaw Janowski, Clare L. Killick-Cole, William G. B. Singleton, Emma Campbell, Piotr Walczak, Soumen Khatua, Lukas Faltings, Marc Symons, Julia R. Schneider, Kevin Kwan, John A. Boockvar, Steven S. Gill, J. Miguel Oliveira, Kevin Beccaria, Alexandre Carpentier, Michael Canney, Monica Pearl, Gareth J. Veal, Lisethe Meijer, David A. Walker

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Incorporating conceptual site models into national-scale environmental risk assessments for legacy waste in the coastal zone by Alex L. Riley, Jaime Amezaga, Ian T. Burke, Patrick Byrne, Nick Cooper, Richard A. Crane, Sean D.W. Comber, Catherine J. Gandy, Karen A. Hudson-Edwards, Elin Jennings, Elizabeth Lewis, Stephen Lofts, John M. MacDonald, Heath Malcolm, William M. Mayes, Patrizia Onnis, Justyna Olszewska, Bryan Spears, Adam P. Jarvis

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Developing a career as a GP educationalist: contemporary challenges and workforce solutions by Lamb, EI, Alberti, H, McKechnie, DGJ, Park, S, Pope, L, Thampy, H

“…GP educationalists are crucial in training the future medical workforce and in developing and advancing the field of primary care medical education, yet opportunities in the UK are patchy and varied. …”

Russian real wages before and after 1917: in global perspective by Allen, R, Khaustova, E

“…Real wages dropped to their pre-War level between 1928 and 1937 during the industrialization drive.…”

Individual and collective protective responses during the early phase of the COVID-19 pandemic in 10 different countries: Results from the EUCLID online survey by Julia E. Koller, Karoline Villinger, Nadine C. Lages, Pilvikki Absetz, Melanie Bamert, Cátia Branquinho, Lourdes Chaves-Avilés, Panagiota Dimitropoulou, Ana Lucía Fernández-Fernández, Margarida Gaspar de Matos, Inguna Griskevica, Benicio Gutiérrez-Doña, Nelli Hankonen, Jennifer Inauen, Dimitrinka Jordanova Peshevska, Angelos P. Kassianos, Jelena Kolsenikova, Meta Lavrič, Tamara Mitanovska, Efrat Neter, Vita Poštuvan, Ingrida Trups-Kalne, Jorge Vargas-Carmiol, Harald T. Schupp, Britta Renner

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Analyzing the Effect of Economic Complexity on Income Inequality in Iran by Azad Khanzadi, Ali Tavassoli Nia, Ali Behnia, Maysam Soltani

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Dynamic knowledge graph approach for modelling the decarbonisation of power systems by Xie, Wanni, Farazi, Feroz, Atherton, John, Bai, Jiaru, Mosbach, Sebastian, Akroyd, Jethro, Kraft, Markus

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Automation of Macular Degeneration Classification in the AREDS Dataset, Using a Novel Neural Network Design by Xie L, Vaghefi E, Yang S, Han D, Marshall J, Squirrell D

“…Li Xie,1 Ehsan Vaghefi,1,2 Song Yang,1 David Han,1,2 John Marshall,3 David Squirrell1,4 1Toku Eyes Limited, Auckland, New Zealand; 2School of Optometry and Vision Science, The University of Auckland, Auckland, New Zealand; 3Institute of Ophthalmology, UCL, London, UK; 4Department of Ophthalmology, Auckland District Health Board, Auckland, New ZealandCorrespondence: Ehsan Vaghefi, Tel +6493737599, Email e.vaghefi@auckland.ac.nzPurpose: To create an ensemble of Convolutional Neural Networks (CNNs), capable of detecting and stratifying the risk of progressive age-related macular degeneration (AMD) from retinal photographs.Design: Retrospective cohort study.Methods: Three individual CNNs are trained to accurately detect 1) advanced AMD, 2) drusen size and 3) the presence or otherwise of pigmentary abnormalities, from macular centered retinal images were developed. …”
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The impact of disruptive powertrain technologies on energy consumption and carbon dioxide emissions from heavy-duty vehicles by Andrew Smallbone, Boru Jia, Penny Atkins, Anthony Paul Roskilly

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Efficacy of Xpert in tuberculosis diagnosis based on various specimens: a systematic review and meta-analysis by Xue Gong, Yunru He, Kaiyu Zhou, Yimin Hua, Yifei Li

“…Where appropriate, meta-analysis was performed using random-effects models. The risk of bias and level of evidence was assessed using the Quality in Prognosis Studies tool and a modified version of the Grading of Recommendations Assessment, Development, and Evaluation. …”
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Cost minimization analysis of nasopharyngoscope reprocessing in community practice by Ameen Biadsee, Lauren Crosby, Winsion Chow, Leigh J Sowerby

“…Four manual techniques were evaluated: (1) soak with ortho-phthalaldehyde solution (Cidex-OPA; Advanced Sterilization Products, Johnson and Johnson Inc., Markham, Canada), (2) soak with accelerated hydrogen peroxide solution (Revital-Ox; Steris Canada Inc., Mississauga, Canada), (3) disinfection with chlorine dioxide wipe (Tristel Trio Wipes System; Tristel plc., Cambridgeshire, UK), (4) UV-C light system (UV Smart, Delft, The Netherlands). …”
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Prevalence and related factors of cognitive frailty in diabetic patients in China: a systematic review and meta-analysis by Junjie Peng, Limei Ming, Jiaming Wu, Yunchuan Li, Shuhua Yang, Qin Liu, Qin Liu

“…Combined estimates showed that depression, malnutrition, advanced age (≥70, ≥80), combined chronic diseases ≥4 and glycated hemoglobin ≥8.5 were risk factors for CF in diabetics patients in China, with regular exercise and high education level (≥ college) as protective factors.ConclusionCognitive frailty was common in diabetic patients in China. …”
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Utilising artificial intelligence to determine patients at risk of a rare disease: idiopathic pulmonary arterial hypertension by David G. Kiely, Orla Doyle, Edmund Drage, Harvey Jenner, Valentina Salvatelli, Flora A. Daniels, John Rigg, Claude Schmitt, Yevgeniy Samyshkin, Allan Lawrie, Rito Bergemann

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The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study by Ioannidou, A, Watts, EL, Perez-Cornago, A, Platz, EA, Mills, IG, Key, TJ, Travis, RC, Tsilidis, KK, Zuber, V

“…We used a two-sample summary-level Mendelian randomisation (MR) approach with both univariable and multivariable (MVMR) models and utilised a variety of robust methods and sensitivity analyses to assess the possibility of MR assumptions violation. …”

Impaired prefrontal activity to regulate the intrinsic motivation-action link in schizophrenia by Kazuyoshi Takeda, Madoka Matsumoto, Yousuke Ogata, Keiko Maida, Hiroki Murakami, Kou Murayama, Keigo Shimoji, Takashi Hanakawa, Kenji Matsumoto, Kazuyuki Nakagome

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Polyvinyl Alcohol (PVA)-Based Nanoniosome for Enhanced in vitro Delivery and Anticancer Activity of Thymol by Abdihaji M, Mirzaei Chegeni M, Hadizadeh A, Farrokhzad N, Kheradmand Z, Fakhrfatemi P, Faress F, Moeinabadi-Bidgoli K, Noorbazargan H, Mostafavi E

“…Mohammadreza Abdihaji,1,* Masoumeh Mirzaei Chegeni,2,* Alireza Hadizadeh,3 Negar Farrokhzad,4 Zahra Kheradmand,5 Parastoo Fakhrfatemi,6 Fardad Faress,7 Kasra Moeinabadi-Bidgoli,8 Hassan Noorbazargan,9 Ebrahim Mostafavi10,11 1Department of Biology, The Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN, USA; 2Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran; 3Research Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran; 4Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; 5Department of Agriculture, Islamic Azad University Maragheh Branch, Maragheh, Iran; 6Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran; 7Department of Business, Data Analysis, The University of Texas Rio Grande Valley (UTRGV), Edinburg, TX, USA; 8Basic and Molecular Epidemiology of Gastroenterology Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 9Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 10Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA; 11Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA*These authors contributed equally to this workCorrespondence: Ebrahim Mostafavi, Email ebimsv@stanford.edu; ebi.mostafavi@gmail.comIntroduction: There is an unmet need to develop potent therapeutics against cancer with minimal side effects and systemic toxicity. …”
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Spoken Latin: Learning, Teaching, Lecturing and Research by A. Gratius Avitus

“…My experiences both as a learner and as a teacher of Latin have led me to the conviction that speaking Latin advances a more nuanced understanding of the language, and leads to an enhanced level of reading fluency and greater ease in engaging closely with the text. …”
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Verification and Validation of Model-Scale Turbine Performance and Control Strategies for the IEA Wind 15 MW Reference Wind Turbine by Nicole Mendoza, Amy Robertson, Alan Wright, Jason Jonkman, Lu Wang, Roger Bergua, Tri Ngo, Tuhin Das, Mohammad Odeh, Kazi Mohsin, Francesc Fabregas Flavia, Benjamin Child, Galih Bangga, Matthew Fowler, Andrew Goupee, Richard Kimball, Eben Lenfest, Anthony Viselli

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