Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells by Agata Sofia Assuncao Carreira, Silvia Ravera, Chiara Zucal, Natthakan Thongon, Caffa Irene, Cecilia Astigiano, Nadia Bertola, Arianna Buongiorno, Michela Roccuzzo, Alessandra Bisio, Barbara Pardini, Alessio Nencioni, Santina Bruzzone, Alessandro Provenzani

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Ablative and non-surgical therapies for early and very early hepatocellular carcinoma: a systematic review and network meta-analysis by Ros Wade, Emily South, Sumayya Anwer, Sahar Sharif-Hurst, Melissa Harden, Helen Fulbright, Robert Hodgson, Sofia Dias, Mark Simmonds, Ian Rowe, Patricia Thornton, Alison Eastwood

“…MWA and resection are the first-line standard of care for single HCC ≤ 3 cm in the UK. The uptake of specific ablative therapies in the UK appears to be based more on technological advancements and ease or speed of use than on high-quality evidence demonstrating superior clinical effectiveness. …”
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Identification of genomic variations of Azeri buffaloes using whole genome sequencing by Milad Hosseini, Hossein Moradi shahrbabak, Mohamad Moradi shahrbabak

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Charting a Course for Smartphones and Wearables to Transform Population Health Research by William G Dixon, Sabine N van der Veer, Syed Mustafa Ali, Lynn Laidlaw, Richard J B Dobson, Cathie Sudlow, Tim Chico, Jacqueline A L MacArthur, Aiden Doherty

“… The use of data from smartphones and wearable devices has huge potential for population health research, given the high level of device ownership; the range of novel health-relevant data types available from consumer devices; and the frequency and duration with which data are, or could be, collected. …”
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From "wading through treacle" to "making haste slowly": A comprehensive yet parsimonious model of drivers and challenges to implementing patient data sharing projects based on an E... by Mila Petrova, Stephen Barclay

“…The study also had a strong applied goal: to derive specific and non-trivial recommendations for advancing data sharing projects, particularly ones in early stages of development and implementation. …”
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Reverse translational approaches to population neuroimaging: using rodent models to interpret genetic associations with MRI by Tisca, C

“…</p> <p>This thesis proposes to investigate key findings from the UK Biobank population neuroimaging studies using mouse models. …”

Annual and individual patterns in the behavioural cycle of the Manx shearwater, Puffinus puffinus by Kirk, H

“…Using a dataset of Manx shearwater migration tracks gathered by geolocation tracking programmes on 5 UK islands, individual consistency, colony-level, annual and sex-differences in the phenology of migrations are investigated.…”

Applications of social data science to environmental communication on social media by Sanford, M

“…It also discusses contributions of the thesis as a whole, bringing the findings of each study into conversation with one another to motivate the importance for future research to 1) take increasingly interdisciplinary approaches to the study of environmental activism and evaluations of its effectiveness, and 2) move away from social media-only studies and connect social media dynamics to micro- and macro-level offline outcomes.</p>…”

Anti-hyperglycemic contours of Madhugrit are robustly translated in the Caenorhabditis elegans model of lipid accumulation by regulating oxidative stress and inflammatory response by Acharya Balkrishna, Acharya Balkrishna, Acharya Balkrishna, Vivek Gohel, Nishit Pathak, Meenu Tomer, Malini Rawat, Rishabh Dev, Anurag Varshney, Anurag Varshney, Anurag Varshney

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Inflammatory biomarkers and cognitive functioning in individuals with euthymic bipolar disorder: exploratory study by Rebecca Strawbridge, Rowena Carter, Francesco Saldarini, Dimosthenis Tsapekos, Allan H. Young

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Physical activity in young children across developmental and health states: the ActiveCHILD studyResearch in context by Niina Kolehmainen, Christopher Thornton, Olivia Craw, Mark S. Pearce, Laura Kudlek, Kianoush Nazarpour, Laura Cutler, Esther Van Sluijs, Tim Rapley

“…Using data from an inclusive UK cohort, ActiveCHILD, we investigated relationships between objectively measured physical activity, child development, social context, and health-related quality of life (HRQoL). …”
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Cognitive Therapy for Anxiety Disorders: Current Status and Future Challenges by McManus, F, Grey, N, Shafran, R

“…It is concluded that the major challenge currently facing CBT for anxiety disorders in the UK is how to meet the increased demand for provision whilst maintaining high levels of efficacy and effectiveness. …”

Emerging concepts: linking hypoxic signaling and cancer metabolism by Lyssiotis, C A, Muñoz-Pinedo, C, Emerling, B M, Vander Heiden, Matthew G.

“…The Joint Keystone Symposia on Cancer and Metabolism and Advances in Hypoxic Signaling: From Bench to Bedside were held in Banff, Alberta, Canada from 12 to 17 February 2012. …”
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Impacts of reducing scattering and absorbing aerosols on the temporal extent and intensity of South Asian summer monsoon and East Asian summer monsoon by C. Fang, C. Fang, J. M. Haywood, J. M. Haywood, J. Liang, J. Liang, B. T. Johnson, Y. Chen, Y. Chen, B. Zhu

“…For SCT, the combination of the early transition of land–sea thermal contrast and sea level pressure gradient during the pre-monsoon season, together with the late transition in the post-monsoon season associated with the tropospheric warming, advances the monsoon onset but delays its withdrawal, which leads to an extension of the summer rainy season across South Asia and East Asia. …”
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Adversity and imagery: a developmental psychopathology lens by Lau-Zhu, A

“…These included aspects of capabilities (knowledge and skills), opportunities (resources, organisational context, and empowerment of youth), and motivations (habit change, emotional experiences, and professional identity/role). Targeting both staff-level and organisation-level barriers to digital risk assessments in CAMHS is crucial. …”

Haemoglobinopathies care and cure: Have we reached the end? by John Porter

“…Disease prevention is a key element to management of both sickle and thalassaemia syndromes but implementation has been highly variable both geographically and even between these conditions at a local level. Prevention of births with sickle cell disorders have been less effective than for thalassaemia, even in countries such as the UK which share the same prevention programs for these conditions. …”
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Involvement of a BH3-only apoptosis sensitizer gene Blm-s in hippocampus-mediated mood control by Pei-Hsin Huang, Tsung-Ying Yang, Chia-Wei Yeh, Sheng-Min Huang, Ho-Ching Chang, Yun-Fen Hung, Wen-Chia Chu, Kuan-Hung Cho, Tzu-Pin Lu, Po-Hsiu Kuo, Li-Jen Lee, Li-Wei Kuo, Cheng-Chang Lien, Hwai-Jong Cheng

“…Abstract Mood disorders are an important public health issue and recent advances in genomic studies have indicated that molecules involved in neurodevelopment are causally related to mood disorders. …”
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Schooling and cognitive outcomes from childhood to youth: a longitudinal analysis by Rolleston, C, James, Z

Ethnic minority children's and adults' perceptions and experiences of schooling in Vietnam: A case study of the Cham H'Roi by Vu, T

FtsH4 protease controls biogenesis of the PSII complex by dual regulation of high light-inducible proteins by Vendula Krynická, Petra Skotnicová, Philip J. Jackson, Samuel Barnett, Jianfeng Yu, Anna Wysocka, Radek Kaňa, Mark J. Dickman, Peter J. Nixon, C. Neil Hunter, Josef Komenda

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