Association between socio-economic status and non-communicable disease risk in young adults from Kenya, South Africa, and the United Kingdom by Asanda Mtintsilana, Ashleigh Craig, Witness Mapanga, Siphiwe N. Dlamini, Shane A. Norris

“…Utilising multi-country study designs can improve our understanding of how socio-economic context shapes the aetiology of NCDs, and this has great potential to advance global health interventions. We examined the association between socio-economic status (SES) and NCD risk, and the potential confounding effects of smoking and alcohol intake in young adults (18–35-year-olds) from Kenya, South Africa (SA), and the United Kingdom (UK). …”
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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer by Arnaud Blomme, Coralie Peter, Ernest Mui, Giovanny Rodriguez Blanco, Ning An, Louise M Mason, Lauren E Jamieson, Grace H McGregor, Sergio Lilla, Chara Ntala, Rachana Patel, Marc Thiry, Sonia H Y Kung, Marine Leclercq, Catriona A Ford, Linda K Rushworth, David J McGarry, Susan Mason, Peter Repiscak, Colin Nixon, Mark J Salji, Elke Markert, Gillian M MacKay, Jurre J Kamphorst, Duncan Graham, Karen Faulds, Ladan Fazli, Martin E Gleave, Edward Avezov, Joanne Edwards, Huabing Yin, David Sumpton, Karen Blyth, Pierre Close, Daniel J Murphy, Sara Zanivan, Hing Y Leung

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Emergent constraints for the climate system as effective parameters of bulk differential equations by C. Huntingford, P. M. Cox, P. M. Cox, M. S. Williamson, M. S. Williamson, J. J. Clarke, P. D. L. Ritchie

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Tumor Growth Rate Estimates Are Independently Predictive of Therapy Response and Survival in Recurrent High-Grade Serous Ovarian Cancer Patients by Thomas Bartl, Jasmine Karacs, Caroline Kreuzinger, Stephanie Pfaffinger, Jonatan Kendler, Cristina Ciocsirescu, Andrea Wolf, Alexander Reinthaller, Elias Meyer, Maximilian Brandstetter, Magdalena Postl, Eva Langthaler, Elena Braicu, Ignace Vergote, Paula Cunnea, Charlie Gourley, Wolfgang D. Schmitt, Dan Cacsire Castillo-Tong, Christoph Grimm

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Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries: a public health framework by Andrea Beaton, Babar S Hasan, Dominique Vervoort, Massimo Caputo, Raman Krishna Kumar, Rajesh Sharma, Christopher Hugo-hamman, sohail khan, Gary Sholler, Bistra Zheleva, William M Novick, Nestor F Sandoval, Kathy J Jenkins, Liesl J Zuhlke, Kokila Lakhoo, paul Barach, Eltayeb Ahmed, Tahmina Banu, Vijayakumar Raju, Sanjiv Nichani, Ashraf S Harahsheh, Muneer Amanullah, Dorothy Pearson, Fenny Shidhika, Areesh Bhatti, Shazia Mohsin, Sulafa Ali, Annette Ansong, Ralph Morton Bolman, Bruna Cury Borim, John P Breinholt, Edward Callus, Marcelo Cardarelli, Tomas Chalela Hernandez, Ulisses Alexandre Croti, Yayehyirad M Ejigu, Kathleen Fenton, Anu Gomanju, Peter Hesslein, Jacques Kpodonu, Mahim Malik, David Overman, Alexis Palacios-Macedo Quenot, Ceeya Patton Bolman, Shelagh Ross, Sivakumar Sivalingam, Amy Verstappen

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A Scoping Review on the Ethical Issues in the Use of CRISPR-Cas9 in the Creation of Human Disease Models by Russell Franco D’Souza, Mary Mathew, Krishna Mohan Surapaneni

“…The articles emphasised the bioethical issues related to CRISPR-Cas9 technology and gene editing while also shedding light on the current level of research in the field. The studies included different countries, with the maximum number of papers from the United States of America (USA), followed by the United Kingdom (UK), China, Turkey, Spain, Canada, Pakistan, Australia, Italy, France, Korea, and Sri Lanka. …”
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Elevated C-reactive protein mediates the liver-brain axis: a preliminary studyResearch in context by Rongtao Jiang, Jing Wu, Matthew Rosenblatt, Wei Dai, Raimundo X. Rodriguez, Jing Sui, Shile Qi, Qinghao Liang, Bin Xu, Qinghua Meng, Vince D. Calhoun, Dustin Scheinost

“…Neuroimaging analyses revealed significant associations between liver fibrosis and reduced regional GMVs, primarily in the hippocampus, thalamus, ventral striatum, parahippocampal gyrus, brain stem, and cerebellum. CRP levels were significantly higher in adults with advanced liver fibrosis than those without, indicating an elevated systemic inflammation. …”
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Forecasting local COVID-19/Respiratory Disease mortality via national longitudinal shopping data: the case for integrating digital footprint data into early warning systems by James Goulding, Elizabeth Dolan, Gavin Long, Anya Skatova, John Harvey, Gavin Smith, Laila Tata

“…In Study 1, XGBoost models were able to optimally predict the number of COVID deaths 21 days in advance (R2=0.71***), significantly outperforming models based on official COVID case data alone at local-area levels (R2=0.44**). …”
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Modelling of the Exchange Rate Volatility and Uncertainty Impacts on Agriculture Import: Evidence from Iran by Ehsan Rajabi

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Extra-coronary arterial disease: incidence, projected future burden, risk factors and prevention by Howard, D

“…For acute aortic disease, I aimed to assess the risk factors associated with acute abdominal aortic aneurysms (AAA) and the population impact of the current UK AAA screening programme; and the incidence, risk factors, outcome, and projected future burden of acute aortic dissection. …”

Breaking new ground: New Zealand Certificates of Steiner Education by Neil Boland, Neil Boland, Karen Brice-Geard, Amanda Bell, Christine Cook

“…This article draws on the experiences of one of the developers of the qualification and two teachers in schools using the certificate in the UK, and outlines some of the challenges faced when breaking new ground in the advancement of Waldorf education internationally.…”
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Effects of Sacubitril/Valsartan on Exercise Capacity in Patients with Heart Failure with Reduced Ejection Fraction and the Role of Percentage of Delayed Enhancement Measured by Car... by Cinzia Nugara, Francesco Giallauria, Giuseppe Vitale, Silvia Sarullo, Giovanni Gentile, Francesco Clemenza, Annamaria Lo Voi, Antonino Zarcone, Elio Venturini, Gabriella Iannuzzo, Andrew JS Coats, Filippo M Sarullo

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Essays on the simulation-based estimation of dynamic discrete choice models by Waltmann, B

“…</p> <p>In this thesis, I propose new tools for estimating these models with a higher degree of accuracy at any given level of computational resources and model complexity. …”

An annotation scheme for Rhetorical Figures by Randy Allen Harris, Chrysanne Di Marco, Sebastian Ruan, Cliff O’Reilly

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Progress and prospects of gene therapy in ophthalmology from 2000 to 2022: A bibliometric analysis by Bingyan Li, Wei Tan, Zicong Wang, Haixiang Zhou, Jingling Zou, Yun Li, Shigeo Yoshida, Yedi Zhou

“…Background: Gene therapy is a treatment approach at the genetic level, which brings great advances in many diseases and develops rapidly in recent years. …”
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Impacts of EU Tobacco Products Directive regulations on use of e-cigarettes in adolescents in Great Britain: a natural experiment evaluation by Moore Graham, Hallingberg Britt, Brown Rachel, McKell Jennifer, Van Godwin Jordan, Bauld Linda, Gray Linsay, Maynard Olivia, Mackintosh Anne-Marie, Munafò Marcus, Blackwell Anna, Lowthian Emily, Page Nicholas

“…iii.What other changes to the regulatory context of tobacco and e-cigarettes occurred during the study period in the UK and across UK countries? Methods Our study was a mixed-method natural experimental evaluation. …”
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Structural analysis of global mineral governance system from the perspective of country by Xiaojing Yuan, Zhe Ma, Anjian Wang, Tianjiao Li, Weiqiong Zhong, Bujie Li, Pengyuan Li, Jiangqiao Wei, Hongchang Hao

“…The research findings are as follow: (1) The UK, Germany, France, Sweden, and Canada play pivotal roles in promoting international cooperation as well as leading governance in the governance system. (2) Emerging economies are more actively engaged in these organizations and can promote international cooperation, but lack the capacity to assume leadership roles in governance. (3) The U.S. and China have a stronger ability to lead than to cooperate in the governance system. (4) Most African and South American countries, as well as some European nations, are marginalized in the governance system. (5) Countries with the same needs and similar economic and political conditions belong to the same community: The European countries and the U.S., consumer with a high level of economic and political development but low mineral resource endowment are in the first community. …”
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Using Machine Learning to Detect Theranostic Biomarkers Predicting Respiratory Treatment Response by Vasilis Nikolaou, Sebastiano Massaro, Masoud Fakhimi, Wolfgang Garn

“…Methods: We performed a cross-sectional analysis on a sample of 13,102 adults from the UK household longitudinal study ‘Understanding Society’. …”
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Association of air pollutants and osteoporosis risk: The modifying effect of genetic predisposition by Cheng Xu, Zhenkun Weng, Qian Liu, Jin Xu, Jingjia Liang, Wenxiang Li, Jia Hu, Tao Huang, Yong Zhou, Aihua Gu

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Defining sustainable limits during and after intensification in a maritime agricultural ecosystem by Geoffrey R Squire

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