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  1. 221
    Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation

    Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation by Ray Sagawa, Seiji Sakata, Bo Gong, Yosuke Seto, Ai Takemoto, Satoshi Takagi, Hironori Ninomiya, Noriko Yanagitani, Masayuki Nakao, Mingyon Mun, Ken Uchibori, Makoto Nishio, Yasunari Miyazaki, Yuichi Shiraishi, Seishi Ogawa, Keisuke Kataoka, Naoya Fujita, Kengo Takeuchi, Ryohei Katayama

    Published 2022-01-01
    “…American Society for Clinical investigation…”
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  2. 222
    SLC25A21 downregulation promotes KRAS-mutant colorectal cancer progression by increasing glutamine anaplerosis

    SLC25A21 downregulation promotes KRAS-mutant colorectal cancer progression by increasing glutamine anaplerosis by Sha-Sha Hu, Yue Han, Tian-Yuan Tan, Hui Chen, Jia-Wen Gao, Lan Wang, Min-Hui Yang, Li Zhao, Yi-Qing Wang, Yan-Qing Ding, Shuang Wang

    Published 2023-11-01
    “…American Society for Clinical investigation…”
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  3. 223
    Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn’s disease, and celiac disease

    Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn’s disease, and celiac disease by Tzipi Braun, Katya E. Sosnovski, Amnon Amir, Marina BenShoshan, Kelli L. VanDussen, Rebekah Karns, Nina Levhar, Haya Abbas-Egbariya, Rotem Hadar, Gilat Efroni, David Castel, Camila Avivi, Michael J. Rosen, Anne M. Grifiths, Thomas D. Walters, David R. Mack, Brendan M. Boyle, Syed Asad Ali, Sean R. Moore, Melanie Schirmer, Ramnik J. Xavier, Subra Kugathasan, Anil G. Jegga, Batya Weiss, Chen Mayer, Iris Barshack, Shomron Ben-Horin, Igor Ulitsky, Anthony Beucher, Jorge Ferrer, Jeffrey S. Hyams, Lee A. Denson, Yael Haberman

    Published 2023-07-01
    “…American Society for Clinical investigation…”
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  4. 224
    Intestinal epithelial BLT1 promotes mucosal repair

    Intestinal epithelial BLT1 promotes mucosal repair by Shusaku Hayashi, Chithra K. Muraleedharan, Makito Oku, Sunil Tomar, Simon P. Hogan, Miguel Quiros, Charles A. Parkos, Asma Nusrat

    Published 2022-12-01
    “…American Society for Clinical investigation…”
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  5. 225
    Heterogeneity in the links between sleep arousals, amyloid-β, and cognition

    Heterogeneity in the links between sleep arousals, amyloid-β, and cognition by Daphne O. Chylinski, Maxime Van Egroo, Justinas Narbutas, Martin Grignard, Ekaterina Koshmanova, Christian Berthomier, Pierre Berthomier, Marie Brandewinder, Eric Salmon, Mohamed Ali Bahri, Christine Bastin, Fabienne Collette, Christophe Phillips, Pierre Maquet, Vincenzo Muto, Gilles Vandewalle

    Published 2021-12-01
    “…American Society for Clinical investigation…”
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  6. 226
    N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota

    N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota by Hirohito Abo, Aoi Muraki, Akihito Harusato, Tetsuya Imura, Maki Suzuki, Kohta Takahashi, Timothy L. Denning, Hiroto Kawashima

    Published 2023-08-01
    “…American Society for Clinical investigation…”
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  7. 227
    hnRNPH2 gain-of-function mutations reveal therapeutic strategies and a role for RNA granules in neurodevelopmental disorders

    hnRNPH2 gain-of-function mutations reveal therapeutic strategies and a role for RNA granules in neurodevelopmental disorders by Benjamin A. Kelvington, Ted Abel

    Published 2023-07-01
    “…American Society for Clinical Investigation…”
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  8. 228
    Calcineurin regulates aldosterone production via dephosphorylation of NFATC4

    Calcineurin regulates aldosterone production via dephosphorylation of NFATC4 by Mesut Berber, Sining Leng, Agnieszka Wengi, Denise V. Winter, Alex Odermatt, Felix Beuschlein, Johannes Loffing, David T. Breault, David Penton

    Published 2023-07-01
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  9. 229
    Germline mutations in a DNA repair pathway are associated with familial colorectal cancer

    Germline mutations in a DNA repair pathway are associated with familial colorectal cancer by Pingping Xu, Danfeng Sun, Yaqi Gao, Yi Jiang, Ming Zhong, Gang Zhao, Jinxian Chen, Zheng Wang, Qiang Liu, Jie Hong, Haoyan Chen, Ying-Xuan Chen, Jing-Yuan Fang

    Published 2021-09-01
    “…American Society for Clinical investigation…”
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  10. 230
    Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis

    Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis by James May, Jane A. Mitchell, R. Gisli Jenkins

    Published 2023-09-01
    “…American Society for Clinical Investigation…”
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  11. 231
    The long noncoding RNA THBS1-AS1 promotes cardiac fibroblast activation in cardiac fibrosis by regulating TGFBR1

    The long noncoding RNA THBS1-AS1 promotes cardiac fibroblast activation in cardiac fibrosis by regulating TGFBR1 by Junteng Zhou, Geer Tian, Yue Quan, Qihang Kong, Fangyang Huang, Junli Li, Wenchao Wu, Yong Tang, Zhichao Zhou, Xiaojing Liu

    Published 2023-03-01
    “…American Society for Clinical investigation…”
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  12. 232
    ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models

    ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models by Jie Li, Jingyi Lu, Manman Xu, Shiyu Yang, Tiantian Yu, Cuimiao Zheng, Xi Huang, Yuwen Pan, Yangyang Chen, Junming Long, Chunyu Zhang, Hua Huang, Qingyuan Dai, Bo Li, Wei Wang, Shuzhong Yao, Chaoyun Pan

    Published 2023-01-01
    “…American Society for Clinical Investigation…”
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  13. 233
    Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants

    Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants by Siriruk Changrob, Peter J. Halfmann, Hejun Liu, Jonathan L. Torres, Joshua J.C. McGrath, Gabriel Ozorowski, Lei Li, G. Dewey Wilbanks, Makoto Kuroda, Tadashi Maemura, Min Huang, Nai-Ying Zheng, Hannah L. Turner, Steven A. Erickson, Yanbin Fu, Atsuhiro Yasuhara, Gagandeep Singh, Brian Monahan, Jacob Mauldin, Komal Srivastava, Viviana Simon, Florian Krammer, D. Noah Sather, Andrew B. Ward, Ian A. Wilson, Yoshihiro Kawaoka, Patrick C. Wilson

    Published 2023-04-01
    “…American Society for Clinical Investigation…”
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  14. 234
    Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers

    Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers by Shion A. Lim, Jie Zhou, Alexander J. Martinko, Yung-Hua Wang, Ekaterina V. Filippova, Veronica Steri, Donghui Wang, Soumya G. Remesh, Jia Liu, Byron Hann, Anthony A. Kossiakoff, Michael J. Evans, Kevin K. Leung, James A. Wells

    Published 2022-02-01
    “…American Society for Clinical Investigation…”
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  15. 235
    A role for IL-33–activated ILC2s in eosinophilic vasculitis

    A role for IL-33–activated ILC2s in eosinophilic vasculitis by Maya E. Kotas, Jérémie Dion, Steven Van Dyken, Roberto R. Ricardo-Gonzalez, Claire J. Danel, Camille Taillé, Luc Mouthon, Richard M. Locksley, Benjamin Terrier

    Published 2021-06-01
    “…American Society for Clinical investigation…”
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  16. 236
    Fungal microbiome in inflammatory bowel disease: a critical assessment

    Fungal microbiome in inflammatory bowel disease: a critical assessment by David M. Underhill, Jonathan Braun

    Published 2022-03-01
    “…American Society for Clinical Investigation…”
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  17. 237
    p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes

    p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes by Vitor F. Martins, Samuel A. LaBarge, Alexandra Stanley, Kristoffer Svensson, Chao-Wei Hung, Omer Keinan, Theodore P. Ciaraldi, Dion Banoian, Ji E. Park, Christina Ha, Byron Hetrick, Gretchen A. Meyer, Andrew Philp, Larry L. David, Robert R. Henry, Joseph E. Aslan, Alan R. Saltiel, Carrie. E. McCurdy, Simon Schenk

    Published 2022-01-01
    “…American Society for Clinical investigation…”
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  18. 238
    Supercharged chimeric antigen receptor T cells in solid tumors

    Supercharged chimeric antigen receptor T cells in solid tumors by Ayush Pant, Christopher M. Jackson

    Published 2022-08-01
    “…American Society for Clinical Investigation…”
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  19. 239
    Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long COVID

    Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long COVID by John P. Haran, Evan Bradley, Abigail L. Zeamer, Lindsey Cincotta, Marie-Claire Salive, Protiva Dutta, Shafik Mutaawe, Otuwe Anya, Mario Meza-Segura, Ann M. Moormann, Doyle V. Ward, Beth A. McCormick, Vanni Bucci

    Published 2021-10-01
    “…American Society for Clinical investigation…”
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  20. 240
    HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease

    HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease by Alicia J. Little, Ping-Min Chen, Matthew D. Vesely, Rahanna N. Khan, Jacob Fiedler, James Garritano, Fahrisa I. Maisha, Jennifer M. McNiff, Joe Craft

    Published 2023-08-01
    “…American Society for Clinical investigation…”
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