A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton by Janssen, Erin, Tohme, Mira, Hedayat, Mona, Leick, Marion, Ramesh, Narayanaswamy, Massaad, Michel J., Ullas, Sumana, Azcutia, Veronica, Goodnow, Christopher C., Randall, Katrina L., Qiao, Qi, Wu, Hao, Al-Herz, Waleed, Cox, Dianne, Hartwig, John, Luscinskas, Francis W., Geha, Raif S., Kumari, Sudha, Irvine, Darrell J

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Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression by Menheniott, Trevelyan R., O’Connor, Louise, Chionh, Yok Teng, Däbritz, Jan, Scurr, Michelle, Rollo, Benjamin N., Ng, Garrett Z., Jacobs, Shelley, Catubig, Angelique, Kurklu, Bayzar, Mercer, Stephen, Minamoto, Toshinari, Ong, David E., Ferrero, Richard L., Wang, Timothy C., Sutton, Philip, Judd, Louise M., Giraud, Andrew S., Fox, James G

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Beyond antigens and adjuvants: formulating future vaccines by Moyer, Tyson, Zmolek, Andrew Charles, Irvine, Darrell J

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TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage by Taylor, Roslyn A., Chang, Che-Feng, Hammond, Matthew D., Grory, Brian Mac, Ai, Youxi, Steinschneider, Arthur F., Renfroe, Stephen C., Askenase, Michael H., McCullough, Louise D., Kasner, Scott E., Mullen, Michael T., Hafler, David A., Sansing, Lauren H., Love, John C, Goods, Brittany A.

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Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism by Zang, Ying, Lyman, Katherine, Guo, Baolin, Wu, Shengxi, Gerfen, Charles R., Wang, Wenting, Li, Chenchen, Chen, Qian, Van der Goes, Marie-Sophie, Hawrot, James, Yao, Annie, Gao, Xian, Lu, Congyi, Zhang, Qiangge, Wang, Dongqing, Fu, Zhanyan, Feng, Guoping

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Circulating CXCR5[superscript +]CXCR3[superscript +]PD-1[superscript lo] Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth by Martin-Gayo, Enrique, Cronin, Jacqueline, Hickman, Taylor, Ouyang, Zhengyu, Lindqvist, Madelene, Schulze zur Wiesch, Julian, Cubas, Rafael, Porichis, Filippos, van Lunzen, Jan, Haddad, Elias K., Walker, Bruce D., Kaufmann, Daniel E., Lichterfeld, Mathias, Yu, Xu G., Kolb, Kellie Elizabeth, Shalek, Alexander K

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JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition by McKenney, Anna Sophia, Somasundara, Amritha Varshini Hanasoge, Spitzer, Barbara, Intlekofer, Andrew M., Ahn, Jihae, Shank, Kaitlyn, Rapaport, Franck T., Patel, Minal A., Papalexi, Efthymia, Chiu, April, Freinkman, Elizaveta, Akbay, Esra A., Steadman, Mya, Nagaraja, Raj, Yen, Katharine, Teruya-Feldstein, Julie, Wong, Kwok-Kin, Rampal, Raajit, Levine, Ross L., Lau, Allison N., Shihadeh, Alan, Vander Heiden, Matthew G., Thompson, Craig B., Levine, Ross L

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Ly6C[superscript lo] monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy by Jung, Keehoon, Heishi, Takahiro, Khan, Omar Fizal, Kowalski, Piotr S, Incio, Joao, Rahbari, Nuh N., Chung, Euiheon, Clark, Jeffrey W., Willett, Christopher G., Luster, Andrew D., Yun, Seok Hyun, Langer, Robert S, Anderson, Daniel Griffith, Padera, Timothy P., Jain, Rakesh K., Fukumura, Dai

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Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction by Nath, Samir R., Yu, Zhigang, Gipson, Theresa A., Marsh, Gregory B., Yoshidome, Eriko, Robins, Diane M., Todi, Sokol V., Housman, David E, Lieberman, Andrew P.

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Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2 by Yu, Krystle K.Q., Fischinger, Stephanie, Smith, Malisa T., Atyeo, Caroline, Cizmeci, Deniz, Wolf, Caitlin R., Layton, Erik D., Logue, Jennifer K., Aguilar, Melissa S., Shuey, Kiel, Loos, Carolin, Yu, Jingyou, Franko, Nicholas, Choi, Robert Y., Wald, Anna, Barouch, Dan, Koelle, David M., Lauffenburger, Douglas, Chu, Helen Y., Alter, Galit, Seshadri, Chetan

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LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation by Yeboah, Muchaala, Papagregoriou, Charys, Jones, Des C, Chan, HT Claude, Hu, Guangan, McPartlan, Justine S, Schiött, Torbjörn, Mattson, Ulrika, Mockridge, C Ian, Tornberg, Ulla-Carin, Hambe, Björn, Ljungars, Anne, Mattsson, Mikael, Tews, Ivo, Glennie, Martin J, Thirdborough, Stephen M, Trowsdale, John, Frendeus, Björn, Chen, Jianzhu, Cragg, Mark S, Roghanian, Ali

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Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu by Goods, Brittany A, Askenase, Michael H, Markarian, Erica, Beatty, Hannah E, Drake, Riley S, Fleming, Ira, DeLong, Jonathan H, Philip, Naomi H, Matouk, Charles C, Awad, Issam A, Zuccarello, Mario, Hanley, Daniel F, Love, J Christopher, Shalek, Alex K, Sansing, Lauren H

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Loss of Sbds in zebrafish leads to neutropenia and pancreas and liver atrophy by Oyarbide, Usua, Shah, Arish N, Amaya-Mejia, Wilmer, Snyderman, Matthew, Kell, Margaret J, Allende, Daniela S, Calo, Eliezer, Topczewski, Jacek, Corey, Seth J

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Identification of antigen-specific TCR sequences based on biological and statistical enrichment in unselected individuals by Smith, Neal P, Ruiter, Bert, Virkud, Yamini V, Tu, Ang A, Monian, Brinda, Moon, James J, Love, J Christopher, Shreffler, Wayne G

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HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells by Fardoos, Rabiah, Asowata, Osaretin E, Herbert, Nicholas, Nyquist, Sarah K, Zungu, Yenzekile, Singh, Alveera, Ngoepe, Abigail, Mbano, Ian M, Mthabela, Ntombifuthi, Ramjit, Dirhona, Karim, Farina, Kuhn, Warren, Madela, Fusi G, Manzini, Vukani T, Anderson, Frank, Berger, Bonnie, Pers, Tune H, Shalek, Alex K, Leslie, Alasdair, Kløverpris, Henrik N

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Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells by Jiang, Ruoyi, Meng, Hailong, Raddassi, Khadir, Fleming, Ira, Hoehn, Kenneth B, Dardick, Kenneth R, Belperron, Alexia A, Montgomery, Ruth R, Shalek, Alex K, Hafler, David A, Kleinstein, Steven H, Bockenstedt, Linda K

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Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity by Jundi, Bakr, Lee, Do-Hyun, Jeon, Hyungkook, Duvall, Melody G, Nijmeh, Julie, Abdulnour, Raja-Elie E, Pinilla-Vera, Mayra, Baron, Rebecca M, Han, Jongyoon, Voldman, Joel, Levy, Bruce D

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Expansion, persistence, and efficacy of donor memory-like NK cells infused for posttransplant relapse by Chen, Jianzhu

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Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium by Abo, Kristine M, Sainz de Aja, Julio, Lindstrom-Vautrin, Jonathan, Alysandratos, Konstantinos-Dionysios, Richards, Alexsia, Garcia-de-Alba, Carolina, Huang, Jessie, Hix, Olivia T, Werder, Rhiannon B, Bullitt, Esther, Hinds, Anne, Falconer, Isaac, Villacorta-Martin, Carlos, Jaenisch, Rudolf, Kim, Carla F, Kotton, Darrell N, Wilson, Andrew A

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Trauma-induced heme release increases susceptibility to bacterial infection by Lee, Ghee Rye, Gallo, David, Alves de Souza, Rodrigo W, Tiwari-Heckler, Shilpa, Csizmadia, Eva, Harbison, James D, Shankar, Sidharth, Banner-Goodspeed, Valerie, Yaffe, Michael B, Longhi, Maria Serena, Hauser, Carl J, Otterbein, Leo E

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