Characterization of pathogenic monoclonal autoantibodies derived from muscle-specific kinase myasthenia gravis patients by Takata, K, Stathopoulos, P, Cao, M, Mané-Damas, M, Fichtner, M, Benotti, E, Jacobson, L, Waters, P, Irani, S, Martinez-Martinez, P, Beeson, D, Losen, M, Vincent, A, Nowak, R, O'Connor, K

“…American Society for Clinical Investigation…”

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes. by Yip, B, Steeples, V, Repapi, E, Armstrong, R, Llorian, M, Roy, S, Shaw, J, Dolatshad, H, Taylor, S, Verma, A, Bartenstein, M, Vyas, P, Cross, N, Malcovati, L, Cazzola, M, Hellström-Lindberg, E, Ogawa, S, Smith, C, Pellagatti, A, Boultwood, J

“…American Society for Clinical Investigation…”

Maternal high-fat diet during lactation reprograms the dopaminergic circuitry in mice by Lippert, RN, Hess, S, Klemm, P, Burgeno, LM, Jahans-Price, T, Walton, ME, Kloppenburg, P, Brüning, JC

“…American Society for Clinical Investigation…”

Tireless surveillance by exhausted T cells by Dustin, ML

“…American Society for Clinical Investigation…”

ROS producing immature neutrophils in Giant Cell Arteritis are linked to vascular pathologies by Wang, L, Ai, Z, Khoyratty, TE, Zec, K, Eames, HL, van Grinsven, E, Hudak, A, Morris, S, Ahern, DJ, Monaco, C, Eruslanov, EB, Luqmani, R, Udalova, IA

“…American Society for Clinical Investigation…”

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency by Cottineau, J, Kottemann, M, Lach, F, Kang, Y, Vély, F, Deenick, E, Lazarov, T, Gineau, L, Wang, Y, Farina, A, Chansel, M, Lorenzo, L, Piperoglou, C, Ma, C, Nitschke, P, Belkadi, A, Itan, Y, Boisson, B, Jabot-Hanin, F, Picard, C, Bustamante, J, Eidenschenk, C, Boucherit, S, Aladjidi, N, Lacombe, D, Barat, P, Qasim, W, Hurst, J, Pollard, A, Uhlig, H, Fieschi, C, Michon, J, Bermudez, V, Abel, L, de Villartay, J, Geissmann, F, Tangye, S, Hurwitz, J, Vivier, E, Casanova, J, Smogorzewska, A, Jouanguy, E

“…American Society for Clinical Investigation…”

Harnessing FOXP3+ regulatory T cells for transplantation tolerance. by Waldmann, H, Hilbrands, R, Howie, D, Cobbold, S

“…American Society for Clinical Investigation…”

Hepatic hepcidin/intestinal HIF-2a axis maintains iron absorption during iron deficiency and overload by Schwartz, A, Das, N, Ramakrishnan, S, Jain, C, Jurkovic, M, Wu, J, Nemeth, E, Lakhal-Littleton, S, Colacino, J, Shah, Y

“…American Society for Clinical Investigation…”

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction by Akbar, N, Digby, JE, Cahill, TJ, Tavare, AN, Corbin, AL, Saluja, S, Dawkins, S, Edgar, L, Rawlings, N, Ziberna, K, McNeill, E, Johnson, E, Aljabali, AA, Dragovic, RA, Rohling, M, Belgard, TG, Udalova, IA, Greaves, DR, Channon, KM, Riley, PR, Anthony, DC, Choudhury, RP

“…American Society for Clinical Investigation…”

Fully automated, real-time 3D-ultrasound segmentation to estimate first trimester placental volume using deep learning by Looney, P, Stevenson, G, Nicolaides, K, Plasencia, W, Molloholli, M, Natsis, S, Collins, S

“…American Society for Clinical Investigation…”

Median eminence blood flow influences food intake by regulating ghrelin access to the metabolic brain by Romano, N, Lafont, C, Campos, P, Guillou, A, Fiordelisio, T, Hodson, DJ, Mollard, P, Schaeffer, M

“…American Society for Clinical investigation…”

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses by Sadiku, P, Willson, JA, Dickinson, RS, Murphy, F, Harris, AJ, Lewis, A, Sammut, D, Mirchandani, AS, Ryan, E, Watts, ER, Thompson, AAR, Marriott, HM, Dockrell, DH, Taylor, CT, Schneider, M, Maxwell, PH, Chilvers, ER, Mazzone, M, Moral, V, Pugh, CW, Ratcliffe, PJ, Schofield, CJ, Ghesquiere, B, Carmeliet, P, Whyte, MK, Walmsley, SR

“…American Society for Clinical Investigation…”

The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes by Seelig, E, Howlett, J, Porter, L, Truman, L, Heywood, J, Kennet, J, Arbon, E, Anselmiova, K, Walker, N, Atkar, R, Pekalski, M, Rytina, E, Evans, M, Wicker, L, Todd, J, Mander, A, Bond, S, Waldron-Lynch, F

“…American Society for Clinical Investigation…”

Controlled human malaria infection with a clone of Plasmodium vivax with high quality genome assembly by Minassian, AM, Themistocleous, Y, Silk, SE, Barrett, JR, Kemp, A, Quinkert, D, Nielsen, CM, Edwards, NJ, Rawlinson, TA, Ramos Lopez, F, Roobsoong, W, Ellis, KJ, Cho, J-S, Aunin, E, Otto, TD, Reid, AJ, Bach, FA, Labbé, GM, Poulton, ID, Marini, A, Zaric, M, Mulatier, M, Lopez Ramon, R, Baker, M, Mitton, CH, Sousa, JC, Rachaphaew, N, Kumpitak, C, Maneechai, N, Suansomjit, C, Piteekan, T, Hou, MM, Khozoee, B, McHugh, K, Roberts, DJ, Lawrie, AM, Blagborough, AM, Nugent, FL, Taylor, IJ, Johnson, KJ, Spence, PJ, Sattabongkot, J, Biswas, S, Rayner, JC, Draper, SJ

“…American Society for Clinical Investigation…”

Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids by Luukkonen, PK, Nick, A, Hölttä-Vuori, M, Thiele, C, Isokuortti, E, Lallukka-Brück, S, Zhou, Y, Hakkarainen, A, Lundbom, N, Peltonen, M, Orho-Melander, M, Orešič, M, Hyötyläinen, T, Hodson, L, Ikonen, E, Yki-Järvinen, H

“…American Society for Clinical Investigation…”

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2 by Pekalski, M, García, A, Ferreira, R, Rainbow, D, Smyth, D, Mashar, M, Brady, J, Savinykh, N, Dopico, X, Mahmood, S, Duley, S, Stevens, H, Walker, N, Cutler, A, Waldron-Lynch, F, Dunger, D, Shannon-Lowe, C, Coles, A, Jones, J, Wallace, C, Todd, J, Wicker, L

“…American Society for Clinical Investigation…”

VEGF regulates local inhibitory complement proteins in the eye and kidney by Keir, L, Firth, R, Aponik, L, Feitelberg, D, Sakimoto, S, Aguilar, E, Welsh, G, Richards, A, Usui, Y, Satchell, S, Kuzmuk, V, Coward, R, Goult, J, Bull, K, Sharma, R, Bharti, K, Westenskow, P, Michael, I, Saleem, M, Friedlander, M

“…American Society for Clinical Investigation…”

Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model by McGonigal, R, Campbell, CI, Barrie, JA, Yao, D, Cunningham, ME, Crawford, CL, Rinaldi, S, Rowan, EG, Willison, HJ

“…American Society for Clinical Investigation…”

Hypomorphic PCNA mutation underlies a human DNA repair disorder by Baple, E, Chambers, H, Cross, H, Fawcett, H, Nakazawa, Y, Chioza, B, Harlalka, G, Mansour, S, Sreekantan-Nair, A, Patton, M, Muggenthaler, M, Rich, P, Wagner, K, Coblentz, R, Stein, C, Last, J, Taylor, A, Jackson, A, Ogi, T, Lehmann, A, Green, C, Crosby, A

“…American Society for Clinical Investigation…”

Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention by Mundra, PA, Barlow, CK, Nestel, PJ, Barnes, EH, Kirby, A, Thompson, P, Sullivan, DR, Alshehry, ZH, Mellett, NA, Huynh, K, Jayawardana, KS, Giles, C, McConville, MJ, Zoungas, S, Hillis, GS, Chalmers, J, Woodward, M, Wong, G, Kingwell, BA, Simes, J, Tonkin, AM, Meikle, PJ, LIPID Study Investigators

“…American Society of Clinical Investigation…”