Does N-methyl-D-aspartate (NMDA) receptor modulation affect emotional processing? Implications for novel antidepressant treatments by Chen, R

“…The delay in onset of action of antidepressants may result in patients suffering increased morbidity due to the persistence of depressed mood and associated symptomatology. More recently, animal and human studies suggest that N-methyl-D-aspartate (NMDA) receptors may participate in the pathophysiology of depression and play an important role in effective pharmacological treatment. …”

Causal mechanisms in type 1 diabetes by Rubio Garcia, A

“…</p> <p>These negatively charged sequences match the motifs present in early anti-insulin infiltrates isolated from NOD mice, a T1D animal model, and were also increased in the repertoires of T1D patients I used for validation. …”

The healthiness and sustainability of national and global food based dietary guidelines: modelling study by Springmann, M, Spajic, L, Clark, MA, Poore, J, Herforth, A, Webb, P, Rayner, M, Scarborough, P

“…Providing clearer advice on limiting in most contexts the consumption of animal source foods, in particular beef and dairy, was found to have the greatest potential for increasing the environmental sustainability of dietary guidelines, whereas increasing the intake of whole grains, fruits and vegetables, nuts and seeds, and legumes, reducing the intake of red and processed meat, and highlighting the importance of attaining balanced energy intake and weight levels were associated with most of the additional health benefits. …”

Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. by Deltheil, T, Guiard, B, Cerdan, J, David, D, Tanaka, K, Repérant, C, Guilloux, J, Coudoré, F, Hen, R, Gardier, A

“…Thus, BDNF+/- mice can be viewed as an animal model of genetic resistance to serotonergic antidepressant drugs. (2) In wild-type BDNF+/+ mice, the effects of intra-hippocampal (vHi) injection of BDNF (100 ng) in combination with a SSRI was examined by using intracerebral microdialysis and behavioral paradigms that predict an antidepressant- and anxiolytic-like activity of a molecule [the forced swim test (FST) and the open field paradigm (OF) respectively]. …”

Ways of knowing

“…It seems to me that one's position on the graded continuum of opinions about consciousness (as for other controversial and emotionally charged issues such as politics, euthanasia, environmental ethics, abortion, animal rights, etc) is not based on strictly rational arguments or proven facts, but rather stems from a set of beliefs that each one of us have, a set of beliefs which has evolved through nothing more specific than having lived a life, read certain books, conversed with certain people and a range of other factors, most of us would be hard-pressed to identify. …”

The island syndrome in birds by Jezierski, MT

“…Clutch size has been at the forefront of avian life history research since David Lack’s studies, and its variation has significant consequences for animal fitness. I explored variation in clutch size for some 4,500 bird species, to examine whether average clutch size differs between island and continental species (<strong>Chapter 2</strong>). …”

First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: A meta-analysis of observational studies by Dellicour, S, Sevene, E, McGready, R, Tinto, H, Mosha, D, Manyando, C, Rulisa, S, Desai, M, Ouma, P, Oneko, M, Vala, A, Rupérez, M, Macete, E, Menéndez, C, Nakanabo-Diallo, S, Kazienga, A, Valéa, I, Calip, G, Augusto, O, Genton, B, Njunju, E, Moore, K, d'Alessandro, U, Nosten, F, Ter Kuile, F, Stergachis, A

“…BACKGROUND: Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester except in lifesaving circumstances. …”

Patch Augmented Rotator Cuff Surgery (PARCS) feasibility study by Cook, J, Baldwin, M, Cooper, C, Nagra, N, Crocker, J, Glaze, M, Greenall, G, Rangan, A, Kottam, L, Rees, J, Farrar-Hockley, D, Merritt, N, Hopewell, S, Beard, D, Thomas, M, Dritsaki, M, Carr, A

“…Patches have been made using different materials (e.g. human/animal skin or tissue and synthetic materials) and processes (e.g. woven or mesh).…”

Population ecology of the leopard cat (Prionailurus bengalensis) in three commercial forest reserves in Sabah, Malaysia by Azlan Mohamed

“…The non-spatial model had probably overestimated the leopard cat density because it did not take into account the animal movements and the results were highly influenced by the choice of buffer width (half MMDM or full MMDM). …”
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Tourism carrying capacity in marine protected area: A case study of Tunku Abdul Rahman Park, Kota Kinabalu, Sabah by Nasrulhakim Hj. Maidin

“…However, in concern of corals, very few respondents (26%) know that it is an animal and can be leached by sunscreen (35%). Despite the low knowledge, tourists show slight support of the Marine Protected Area, where the Likert-scale of 5 questions resulted in a mean score of 2.36 ± 0.99. …”
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Taxonomy and biogeography of the land snail genus alycaeus (gastropoda: alycaeinae) in Peninsular Malaysia by Foon, Junn Kitt

“…Based on these examined materials, I utilised a more comprehensive set of shell and operculum characters, as well as living animal colour to describe all Alycaeus species in this paper. …”
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Antioxidant potential and Cancer-specific cytotoxic effect of selected marine microalgal extratcs by Ferdous, Umme Tamanna

“…These six marine microalgae are considered safe for human and animal usage as well as frequently used as fish feed and dietary supplements. …”
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UPM pamer 570 reka cipta, penyelidikan dan inovasi pada PRPI by Universiti Putra Malaysia, Bahagian Komunikasi Korporat

“…Selain itu PRPI turut melancarkan produk komersil Monogastric Animal Feed oleh Fakulti Pertanian iaitu produk penggalak tumbesaran ayam tanpa menggunakan suntikan. …”
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Poultry vaccines: an innovation for food safety and security by Bejo, Mohd Hair

“…This can be achieved through advanced knowledge in animal biotechnology and molecular biology. It appears that conventional type vaccines will still be the main type of vaccine produced in the near future, but new generation vaccines hold the promise of more advantages although there is a big horizon to explore before thisbecomes a reality…”
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Properties of vanillin and its effects on colorectal cancer in vitro and in vivo by Ho, Ket Li

“…Following the administration, animal behavior was observed and recorded. After 14 weeks of vanillin administration, the effects of vanillin on blood cells, kidney, liver and brain were studied. …”
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Oil palm empty fruit bunch biochar soil amendment in Amaranthus viridis cultivation to improve crop performance and soil properties by Tan, Wei Loon, Abu Bakar, Rosenani, Ahmad, Siti Hajar, Ishak, Che Fauziah

“…Organic amendments such as compost and animal manure are needed to improve soil health for sustainable agriculture production on these soils. …”
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Enzymatic synthesis of diacylglycerol from palm kernel oil and soy-canola oil blend, and its anti-obesity effects in C57BL/6N mice by Tang, Teck Kim

“…The purified PKDG and SCDG were incorporated into animal feed and their dietary effect in diet-induced obese C57BL/6N mice was investigated. …”
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Chemical Composition, Antioxidative and Cholesterol Lowering Properties of Selected Malaysia Seaweeds by Matanjun, Patricia

“…Chemical analysis of seaweeds comprised of proximate composition, dietary fiber, vitamin C, vitamin E (α-tocopherol), minerals, carotenoids, chlorophylls, fatty acids and amino acids. Animal experimental diets comprised of eight groups: normal diet (N, control group), HCF diet (HCF group), normal diet supplemented with 5% seaweeds (N+KA, N+CL and N+SP groups), and HCF diet supplemented with 5% seaweed (HCF+KA, HCF+CL and HCF+SP groups). …”
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Integrated strategy for the assessment of kidney toxicity: the case of aristolochic acids by Abdullah, Rozaini

“…This PhD thesis aimed to provide additional evidence to demonstrate the potential of an integrated testing strategy using in vitro assays with physiologically based kinetic (PBK) modeling based-reverse dosimetry to predict in vivo toxicity without animal testing. Kidney toxicity was chosen as the toxicity endpoint and aristolochic acids (AAs) were selected as model chemicals. …”
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Comparison of GIP and GLP-1 promoter-mediated insulin expression in Gut K and L-cells for the potential treatment of diabetes mellitus by Rasouli, Mina

“…Finally, the insulin expression efficacy of the reconstructed plasmids with GIP and GLP-1 promoters in lowering the glucose levels was compared in diabetes animal model. To study these hypotheses, neomycin, insulin and GFP genes were inserted downstream of the promoters in 6 different recombinant constructs. …”
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