Systemic antibiotics for chronic suppurative otitis media by Chong, LY, Head, K, Webster, KE, Daw, J, Richmond, P, Snelling, T, Bhutta, MF, Schilder, AGM, Burton, MJ, Brennan-Jones, CG

“…Antibiotics can be used alone or in addition to other treatments for CSOM.…”

The effect of spatiotemporal antibiotic inhomogeneities on the evolution of resistance by Steel, H, Papachristodoulou, A

“…Combating the evolution of widespread antibiotic resistance is one of the most pressing challenges facing modern medicine. …”

Antibiotic resistance is the quintessential One Health issue by Robinson, T, Bu, D, Carrique-Mas, J, Fevre, E, Gilbert, M, Grace, D, Hay, S, Jiwakanon, J, Kakkar, M, Kariuki, S, Laxminarayan, R, Lubroth, J, Magnusson, U, Thi Ngoc, P, Van Boeckel, T, Woolhouse, M

A child with earache. Are antibiotics the best treatment? by Del Mar, C, Glasziou, P

“…A Cochrane review of the literature on the use of antibiotics for acute otitis media shows that the benefits of antibiotic use (reduced pain in those children who go on to suffer pain beyond 24 hours) are offset by adverse events from the antibiotics themselves (gastrointestinal symptoms and rashes). …”

Patients' views on respiratory tract symptoms and antibiotics. by van Duijn, H, Kuyvenhoven, M, Jones, RT, Butler, C, Coenen, S, Van Royen, P

A crystallographic study of the structure of some antibiotics by Diamand, R

Persistence and resistance as complementary bacterial adaptations to antibiotics by Vogwill, T, Comfort, A, Furió, V, MacLean, R

“…Bacterial persistence represents a simple of phenotypic heterogeneity, whereby a proportion of cells in an isogenic bacterial population can survive exposure to lethal stresses such as antibiotics. In contrast, genetically based antibiotic resistance allows for continued growth in the presence of antibiotics. …”

Antibiotics in the community: a typology of user behaviours. by Hawkings, N, Butler, C, Wood, F

“… OBJECTIVES: To contribute to achieving a deep understanding of lay beliefs about antibiotics and develop a typology of antibiotic user behaviours in the community. …”

Antibiotic resistance: Evolution without trade-offs by Reznick, D, King, K

“…Artificial selection for antibiotic resistance in microorganisms reveals why and how expected evolutionary trade-offs between population growth rate and population carrying capacity are not observed in resource-limited environments, with ‘trade-ups’ occurring instead.…”

Antibiotic collateral sensitivity is contingent on the repeatability of evolution by Nichol, D, Rutter, J, Bryant, C, Hujer, AM, Lek, S, Adams, MD, Jeavons, P, Anderson, ARA, Bonomo, RA, Scott, JG

“…Antibiotic resistance represents a growing health crisis that necessitates the immediate discovery of novel treatment strategies. …”

ABC of monitoring drug therapy. Aminoglycoside antibiotics. by Aronson, J, Reynolds, D

Prophylactic antibiotics after operative vaginal delivery by Thompson, KJ, Hirst, JE

Antibiotics for acute infective conjunctivitis in children - Reply by Rose, P, Harnden, A, Brueggemann, A, Perera, R, Mant, D

Antibiotics and shared decision-making in primary care. by Butler, C, Kinnersley, P, Prout, H, Rollnick, S, Edwards, A, Elwyn, G

“…Antibiotics are often prescribed to patients with respiratory tract infections who are unlikely to benefit. …”

The antibiotic course has had its day by Llewelyn, M, Fitzpatrick, J, Darwin, E, Tonkin-Crine, S, Gorton, C, Paul, J, Peto, T, Yardley, L, Hopkins, S, Walker, A

“…With little evidence that failing to complete a prescribed antibiotic course contributes to antibiotic resistance, it’s time for policy makers, educators, and doctors to drop this message, argue Martin Llewelyn and colleagues.…”

Integron activity accelerates the evolution of antibiotic resistance.. by Souque, C, Escudero, JA, MacLean, RC

“…Antibiotic stress induces the expression of an integrase that excises and integrates cassettes, and this unique recombination and expression system is thought to allow bacteria to 'evolve on demand' in response to antibiotic pressure. …”

WGS to predict antibiotic MICs for Neisseria gonorrhoeae by Eyre, D, De Silva, D, Cole, K, Peters, J, Cole, M, Grad, Y, Demczuk, W, Martin, I, Mulvey, M, Crook, D, Walker, A, Peto, T, Paul, J

Topical antibiotics for chronic suppurative otitis media by Brennan-Jones, C, Head, K, Chong, L, Tu, N, Burton, M, Schilder, A, Bhutta, M

“…The objectives are as follows:</p> <p>To assess the effects of topical antibiotics for people with chronic suppurative otitis media (CSOM).…”

Antibiotics for sinusitis-like symptoms in primary care. by Lindbaek, M, Butler, C

Topical antibiotics for chronic suppurative otitis media by Brennan-Jones, CG, Head, K, Chong, L-Y, Burton, MJ, Schilder, AGM, Bhutta, MF

“…</p> <p>The two main comparisons were topical antibiotic compared to a) placebo or no intervention and b) another topical antibiotic (e.g. topical antibiotic A versus topical antibiotic B).…”