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    ARIEL and AMELIA: testing for an accumulation of rare variants using next-generation sequencing data. by Asimit, J, Day-Williams, A, Morris, A, Zeggini, E

    Published 2012
    “…Locus-based tests become necessary due to low power in rare variant single-point association analyses. In addition, variant quality scores are available for sequencing data, but are rarely taken into account. …”
    Journal article
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