Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a... by Melanie Greenland, Elizabeth Jones, Xinxue Liu, Andrew J Pollard, Brian Angus, Susana Camara, Hannah Robinson, Marije Verheul, Jennifer Hill, Myron M Levine, Katherine Emary, Nisha Singh, Naina McCann, Florence Mclean, Young Chan Kim, Kerry Conlin, Maheshi N Ramasamy

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Identifying potential threats to soil biodiversity by Mark Tibbett, Tandra D. Fraser, Sarah Duddigan

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Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-R... by Green, C, Scarselli, E, Voysey, M, Capone, S, Vitelli, A, Nicosia, A, Cortese, R, Thompson, A, Sande, C, de Lara, C, Klenerman, P, Pollard, A

“…years test either a single dose of IM MVA-RSV, one of three combinations of IN or IM PanAd3-RSV prime and PanAd3-RSV or MVA-RSV boost vaccination used in younger volunteers, and a non-vaccinated control group. Study participants are self-selected volunteers who satisfy the eligibility criteria and are assigned to study groups by sequential allocation. …”

The impact of gender equity in agriculture on nutritional status, diets, and household food security: a mixed-methods systematic review by Giacomo Zanello, Helen Harris-Fry, Hayaan Nur, Bhavani Shankar, Chittur Srinivasan, Suneetha Kadiyala

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Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community tr... by Hayward, G, Butler, CC, Yu, L-M, Saville, BR, Berry, N, Dorward, J, Gbinigie, O, van Hecke, O, Ogburn, E, Swayze, H, Bongard, E, Allen, J, Tonner, S, Rutter, H, Tonkin-Crine, S, Borek, A, Judge, D, Grabey, J, de Lusignan, S, Thomas, NPB, Evans, PH, Andersson, MI, Llewelyn, M, Patel, M, Hopkins, S, Hobbs, FDR

Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped... by Ashford, P-A, Knight, C, Heslin, M, Clark, AB, Kanaan, M, Patel, U, Stuart, F, Kabir, T, Grey, N, Murray, H, Hodgekins, J, Reeve, N, Marshall, N, Painter, M, Clarke, J, Russo, D, Stochl, J, Leathersich, M, Pond, M, Fowler, D, French, P, Swart, AM, Dixon-Woods, M, Byford, S, Jones, PB, Perez, J

Protocol for the development and analysis of the Oxford and Reading Cognitive Comorbidity, Frailty and Ageing Research Database - Electronic Patient Records (ORCHARD-EPR) by Boucher, E, Jell, A, Singh , S, Davies, J, Smith, T, Pill, A, Varnai, K, Woods, K, Walliker, D, McColl, A, Shepperd, S, Pendlebury, S

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities by Erica L. Bradshaw, Mary E. Spilker, Richard Zang, Loveleena Bansal, Handan He, Rhys D.O. Jones, Kha Le, Mark Penney, Edgar Schuck, Brian Topp, Alice Tsai, Christine Xu, Marjoleen J.M.A. Nijsen, Jason R. Chan

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Treatment of childhood anxiety disorder in the context of maternal anxiety disorder: a randomised controlled trial and economic analysis. by Creswell, C, Cruddace, S, Gerry, S, Gitau, R, McIntosh, E, Mollison, J, Murray, L, Shafran, R, Stein, A, Violato, M, Voysey, M, Willetts, L, Williams, N, Yu, L, Cooper, P

“…The economic findings highlight the utility of considering the use of a broad range of services when evaluating interventions with this client group.Current Controlled Trials ISRCTN19762288.This trial was funded by the Medical Research Council (MRC) and Berkshire Healthcare Foundation Trust and managed by the National Institute for Health Research (NIHR) on behalf of the MRC-NIHR partnership (09/800/17) and will be published in full in Health Technology Assessment; Vol. 19, No. 38.…”

Assessing the impact of online postal self-sampling for sexually transmitted infections on health inequalities, access to care and clinical outcomes in the UK: protocol for ASSIST,... by Jo Gibbs, Hamish Mohammed, Jonathan Ross, Catherine H Mercer, Elizabeth Murray, Geoff Wong, Louise J Jackson, Jessica Sheringham, Fiona M Burns, Ann K Sullivan, Andrew Copas, Alison R Howarth, David J Crundwell

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Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial... by Gbinigie, O, Ogburn, E, Allen, J, Dorward, J, Dobson, M, Madden, T-A, Yu, L-M, Lowe, DM, Rahman, N, Petrou, S, Richards, D, Hood, K, Patel, M, Saville, BR, Marion, J, Holmes, J, Png, ME, Hayward, G, Lown, M, Harris, V, Jani, B, Hart, N, Khoo, S, Rutter, H, Chalk, J, Standing, JF, Breuer, J, Lavallee, L, Hadley, E, Cureton, L, Benysek, M, Andersson, MI, Francis, N, Thomas, NPB, Evans, P, van Hecke, O, Koshkouei, M, Coates, M, Barrett, S, Bateman, C, Davies, J, Raymundo-Wood, I, Ustianowski, A, Nguyen-Van-Tam, J, Carson-Stevens, A, Hobbs, R, Little, P, Butler, CC

Relationship between Pharmacokinetic Profile and Clinical Efficacy Data of Three Different Forms of Locally Applied Flurbiprofen in the Mouth/Throat by Vit Perlik, Anuradha Kulasekaran, Graça Coutinho, Martin Votava, Jean-Michel Cardot

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Sleep and motor learning in stroke (SMiLES): a longitudinal study investigating sleep-dependent consolidation of motor sequence learning in the context of recovery after stroke by Nele Demeyere, Heidi Johansen-Berg, BARBARA ROBINSON, Matthew Weightman, Emma Garratt, Rachel Teal, Melanie K Fleming, Morgan P Mitchell, Andrew Rudgewick-Brown

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Understanding clinical decision-making in mesothelioma care: a mixed methods study by Najib Rahman, Catherine Henshall, Edward McKeown, Zoe Davey, Helen Walthall, Hannah Ball, Mitra Shahidi, John Park, Paul Dawson, Anand Sundralingam

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Protocol for an OpenSAFELY cohort study collecting patient-reported outcome measures using the TPP Airmid smartphone application and linked big data to quantify the health and econ... by Michael Marks, Mark Jit, Frank Sandmann, Ben Goldacre, Liam Smeeth, Laurie A Tomlinson, Liang-Yu Lin, Emily Herrett, Deb Smith, Jessica Morley, Andrew Briggs, Seb Bacon, Amir Mehrkar, John Parry, Keith Tomlin, Viyaasan Mahalingasivam, Christopher Bates, Benjamin Butler-Cole, Alan Dennison, Ethan Gabriel, Rosalind M M Eggo

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Dextran of Diverse Molecular-Configurations Used as a Blood-Plasma Substitute, Drug-Delivery Vehicle and Food Additive Biosynthesized by <i>Leuconostoc, Lactobacillus</i> and <i>We... by Divakar Dahiya, Poonam Singh Nigam

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Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a... by McCann, N, Emary, K, Singh, N, Mclean, F, Camara, S, Jones, E, Kim, YC, Liu, X, Greenland, M, Conlin, K, Hill, J, Verheul, M, Robinson, H, Angus, B, Ramasamy, MN, Levine, MM, Pollard, AJ

Cardiac abnormalities in Long COVID 1-year post-SARS-CoV-2 infection by Amitava Banerjee, Gregory Y H Lip, Adriana Roca-Fernández, Michael Brady, Matt Kelly, Rajarshi Banerjee, Matthew Robson, Valentina Carapella, Ntobeko Ntusi, Malgorzata Wamil, Melissa Heightman, Andrea Dennis, Sacha Bull, Alessandra Borlotti, Alison Telford, David Monteiro, Helena Thomaides-Brears

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Treatment of childhood anxiety disorder in the context of maternal anxiety disorder: a randomised controlled trial and economic analysis by Cathy Creswell, Susan Cruddace, Stephen Gerry, Rachel Gitau, Emma McIntosh, Jill Mollison, Lynne Murray, Rosamund Shafran, Alan Stein, Mara Violato, Merryn Voysey, Lucy Willetts, Nicola Williams, Ly-Mee Yu, Peter J Cooper

“…Funding: This trial was funded by the Medical Research Council (MRC) and Berkshire Healthcare Foundation Trust and managed by the National Institute for Health Research (NIHR) on behalf of the MRC–NIHR partnership (09/800/17) and will be published in full in Health Technology Assessment; Vol. 19, No. 38.…”
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Separation of Lanthanide Isotopes from Mixed Fission Product Samples by Leah M. Arrigo, Jun Jiang, Zachary S. Finch, James M. Bowen, Staci M. Herman, Larry R. Greenwood, Judah I. Friese, Brienne N. Seiner

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