Mitochondrial carrier 1 (MTCH1) governs ferroptosis by triggering the FoxO1-GPX4 axis-mediated retrograde signaling in cervical cancer cells by Xuan Wang, Yuting Ji, Jingyi Qi, Shuaishuai Zhou, Sitong Wan, Chang Fan, Zhenglong Gu, Peng An, Yongting Luo, Junjie Luo

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SEADETECT: developing an automated detection system to reduce whale-vessel collision risk by Silvia Paoletti, Bob Rumes, Nino Pierantonio, Simone Panigada, Romain Jan, Thomas Folegot, Anita Schilling, Nicolas Riviere, Vincent Carrier, Antoine Dumoulin, David Van Hamme, Gildas Marquis-Laisné, François-Antoine Bruliard, Félix Petitpierre, Damien Demoor

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Clear interests and clouded future : force structure and strategy options for the People's Liberation Army Navy (PLAN) by Pickard, Kevin, Jr

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Low-temperature solution-processed wavelength-tunable perovskites for lasing by Xing, Guichuan, Mathews, Nripan, Lim, Swee Sien, Yantara, Natalia, Liu, Xinfeng, Sabba, Dharani, Grätzel, Michael, Mhaisalkar, Subodh, Sum, Tze Chien

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Anisotropy of magnetic susceptibility study and its significance in the Late Cretaceous-Cenozoic Sanmenxia Basin in the southeastern Shanxi rift, Central China by Kai Jiang, Wentian Liang, Guanzuo Wu, Chengcheng Liu, Xiang Zou, Xuan He, Jiangang Li, Xueting Wang, Boyang Zheng, Qi Shen

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Childhood Rheumatic Diseases and COVID-19 Pandemic: An Intriguing Linkage and a New Horizon by Fatih Haşlak, Mehmet Yıldız, Amra Adrovic, Kenan Barut, Özgür Kasapçopur

“…Several days later, causative viral agent was analyzed with deep sequencing and indicated as a novel coronavirus, officially named 2019 novel coronavirus (2019 nCoV) (3). Coronavirus Study Group (CSG) of the International Commission on Virus Classification named this novel coronavirus “Severe Acute Respiratory syndrome Coronavirus 2 (SARS-CoV-2)” on February 11, 2020 and on the same day, the World Health Organization (WHO) named the disease caused by SARS-CoV-2, “Coronavirus disease-2019 (COVID-19)” (4). …”
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Biodegradable Silk Fibroin Nanocarriers to Modulate Hypoxia Tumor Microenvironment Favoring Enhanced Chemotherapy by Li Bin, Yuxiao Yang, Feiyu Wang, Rong Wang, Hongxin Fei, Siliang Duan, Linling Huang, Na Liao, Shimei Zhao, Xinbo Ma

“…Eventually, SF-based targeted drug carrier provides biocompatibility to reverse hypoxia microenvironment in vivo for enhancing chemotherapy, strikingly suppressing tumor development, and thereby suggesting a promising candidate for drug delivery system.…”
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Developing Electron Microscopy Tools for Profiling Plasma Lipoproteins Using Methyl Cellulose Embedment, Machine Learning and Immunodetection of Apolipoprotein B and Apolipoprotein... by Yvonne Giesecke, Samuel Soete, Katarzyna MacKinnon, Thanasis Tsiaras, Madeline Ward, Mohammed Althobaiti, Tamas Suveges, James E. Lucocq, Stephen J. McKenna, John M. Lucocq

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Working Memory-Related Effective Connectivity in Huntington’s Disease Patients by Jacob Lahr, Jacob Lahr, Lora Minkova, Lora Minkova, Sarah J. Tabrizi, Julie C. Stout, Stefan Klöppel, Stefan Klöppel, Stefan Klöppel, Stefan Klöppel, Elisa Scheller, Elisa Scheller, Elisa Scheller, the TrackOn-HD Investigators, A. Coleman, J. Decolongon, M. Fan, T. Koren, C. Jauffret, D. Justo, S. Lehericy, K. Nigaud, R. Valabrègue, A. Schoonderbeek, E. P. ‘t Hart, H. Crawford, S. Gregory, D. Hensman Moss, E. Johnson, J. Read, G. Owen, M. Papoutsi, C. Berna, A. Razi, G. Rees, R. I. Scahill, D. Craufurd, R. Reilmann, N. Weber, J. Stout, I. Labuschagne, M. Orth, G. B. Landwehrmeyer, D. Langbehn, H. Johnson, J. Long, J. Mills

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The role of cardiac energy metabolism and during stress in hypertrophic and dilated cardiomyopathy. by Dass, S

Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathies. by Zimoń, M, Baets, J, Auer-Grumbach, M, Berciano, J, Garcia, A, Lopez-Laso, E, Merlini, L, Hilton-Jones, D, McEntagart, M, Crosby, A, Barisic, N, Boltshauser, E, Shaw, C, Landouré, G, Ludlow, C, Gaudet, R, Houlden, H, Reilly, M, Fischbeck, K, Sumner, C, Timmerman, V, Jordanova, A, Jonghe, P

“…Hereditary neuropathies form a heterogeneous group of disorders for which over 40 causal genes have been identified to date. …”

<i>CHEK2^p.I157T</i> Mutation Is Associated with Increased Risk of Adult-Type Ovarian Granulosa Cell Tumors by Peter Švajdler, Peter Vasovčák, Marián Švajdler, Monika Šedivcová, Veronika Urbán, Michal Michal, Roman Mezencev

“…Our review of 78 female heterozygous carriers of these mutations (age > 18 years) found strikingly higher proportion of adult-type granulosa cell tumors of the ovary (AGCTs) among ovarian cancers that developed in these women (~36%) compared to women from the general population (1.3%). …”
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The neural correlates and clinical characteristics of psychosis in the frontotemporal dementia continuum and the C9orf72 expansion by Emma M Devenney, Ramon Landin-Romero, Muireann Irish, Michael Hornberger, Eneida Mioshi, Glenda M. Halliday, Matthew C. Kiernan, John R. Hodges

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Dominant mutations in the cation channel gene transient receptor potential vanilloid 4 cause an unusual spectrum of neuropathies by Zimoń, M, Baets, J, Auer-Grumbach, M, Berciano, J, Garcia, A, Lopez-Laso, E, Merlini, L, Hilton-Jones, D, McEntagart, M, Crosby, A, Barisic, N, Boltshauser, E, Shaw, C, Landouré, G, Ludlow, C, Gaudet, R, Houlden, H, Reilly, M, Fischbeck, K, Sumner, C, Timmerman, V, Jordanova, A, Jonghe, P

“…Hereditary neuropathies form a heterogeneous group of disorders for which over 40 causal genes have been identified to date. …”

Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma by Hong Luo, Hao Zhang, Jinning Mao, Hui Cao, Yihao Tao, Guanjian Zhao, Zhiwen Zhang, Nan Zhang, Zaoqu Liu, Jian Zhang, Peng Luo, Yuguo Xia, Yuan Cheng, Zongyi Xie, Quan Cheng, Guodong Liu

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Clinical genomic profiling to identify actionable alterations for very early relapsed triple-negative breast cancer patients in the Chinese population by Liye Wang, Qinglian Zhai, Qianyi Lu, Kaping Lee, Qiufan Zheng, Ruoxi Hong, Shusen Wang

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The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease. by Trachtenberg, A, Filippini, N, Cheeseman, J, Duff, E, Neville, M, Ebmeier, K, Karpe, F, Mackay, C

“…We used functional magnetic resonance imaging (fMRI) to compare the pattern of activation during an episodic encoding task and during a counting Stroop task in 76 adults, aged 32 to 55, with different APOE genotypes (23 ε2/ε3, 20 ε3/ε3, 26 ε3/ε4, and 7 ε4/ε4). Strikingly, participants with an increased risk (ε4 carriers) and with a decreased risk (ε2 carriers) for AD both showed increased activation, relative to ε3 homozygotes, during both tasks. …”

Herpesviruses in brain and Alzheimer's disease. by Lin, W, Wozniak, M, Cooper, R, Wilcock, G, Itzhaki, R

“…In 59% of the AD patients' brains harbouring HHV6, type B is present while 38% harbour both type A and type B, and 3% type A. HSV2 is present at relatively low frequency in brains of both AD patients and normals (13% and 20%), and CMV at rather higher frequencies in the two groups (36% and 35%); in neither case is the difference between the groups statistically significant. …”