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581
Bisphosphonates: mode of action and pharmacology.
Published 2007“…Bisphosphonates are structural analogues of inorganic pyrophosphate but are resistant to enzymatic and chemical breakdown. Bisphosphonates inhibit bone resorption by selective adsorption to mineral surfaces and subsequent internalization by bone-resorbing osteoclasts where they interfere with various biochemical processes. …”
Journal article -
582
Harry A. Williams beyond Soundings: finding God through self-awareness and doubt
Published 2022“…</p> <p>As a homosexual priest initially suppressing his sexual orientation, Williams suffered a mental breakdown which triggered feelings of profound guilt, disapproval and mental paralysis. …”
Thesis -
583
Non-equilibrium dynamics of reaction-diffusion systems
Published 1996“…Below a certain upper critical dimension <em>d<sub>c</sub></em> , this effect results in the breakdown of traditional approaches, such as mean field rate equations. …”
Thesis -
584
The fragments of impegno : interpretations of commitment in contemporary Italian narrative, 1980-1995
Published 1998“…In the six chapters of the main body of my thesis, I consider the further breakdown, in the recent climate of political diffidence, of the traditional sense of commitment to a specific cause, into a fragmentary exposure of a variety of 'minority' issues in the work of individual authors or groups of the 1980s and early 1990s, broadly classifiable under the 'giovani narratori' label. …”
Thesis -
585
Fabrication Of Cooling Jig Using Electro Discharge Machining (Edm)
Published 2002“…A higher breakdown of equipments will affect the delivery to next processes and uncertain level of quality. …”
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Thesis -
586
Minimizing variation order on construction project due to design change
Published 2012“…Based on the above analysis, the results shows that the most significant causes of variation order are design faulty/wrong technical data; duration for design phase too short; and communication breakdown & lack of coordination among consultants. …”
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Thesis -
587
Analysis of the BEAVRS PWR benchmark using SCALE and PARCS
Published 2019-09-01“…The first fuel cycle was simulated, and acceptable agreement with boron letdown curve and measurements were obtained. Finally, conclusions and recommendations for future research were presented.…”
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588
Good Guy or Bad Guy? The Duality of Wild-Type p53 in Hormone-Dependent Breast Cancer Origin, Treatment, and Recurrence
Published 2018-05-01“…“Lactation is at one point perilously near becoming a cancerous process if it is at all arrested”, Beatson, 1896. Most breast cancers arise from the milk-producing cells that are characterized by aberrant cellular, molecular, and epigenetic translation. …”
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589
Effects of Glass Transition and Structural Relaxation on Crystal Nucleation: Theoretical Description and Model Analysis
Published 2020-09-01“…As one of its applications, this theoretical treatment provides a new tool for the explanation of the low-temperature anomaly in nucleation in silicate and polymer glasses (the so-called “breakdown” of CNT at temperatures below the temperature of the maximum steady-state nucleation rate). …”
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590
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591
Defining Coral Bleaching as a Microbial Dysbiosis within the Coral Holobiont
Published 2020-10-01“…The heat-induced breakdown of the symbiosis between the host and its dinoflagellate algae (that is, “bleaching”), is one of the most devastating outcomes for reef ecosystems. …”
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592
Numerical Study on Vortical Flow Structure and Performance Enhancement of Centrifugal Compressor Impeller
Published 2022-08-01“…At 60% of the design flow rate, a vortex breakdown occurred at the tip leakage vortex near the leading edge of the main blade, and a reverse flow at 50% chord length of the main blade’s suction surface. …”
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593
Tracking electricity losses and their perceived causes using nighttime light and social media
Published 2023-12-01“…Summary: Urban environments are intricate systems where the breakdown of critical infrastructure can impact both the economic and social well-being of communities. …”
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594
RELIABILITY ANALYSIS OF FULL-FACE TUNNEL BORING MACHINES WITH THE MONTE CARLO SIMULATION TECHNIQUE
Published 2022-01-01“…Reliability analysis is a practical method based on studying the behaviour of breakdowns and maintenance of machines and systems. …”
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595
A Cross-Country European Efficiency Measurement of Maritime Transport: A Data Envelopment Analysis Approach
Published 2022-04-01“…In transportation management, efficiency is critical for verifying performance and proposing the best countermeasure to meet predetermined goals. …”
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596
Two Types of Wear Mechanisms Governing Transition between Mild and Severe Wear in Ti-6Al-4V Alloy during Dry Sliding at Temperatures of 20–250 °C
Published 2022-02-01“…Two types of wear mechanisms that dominated mild-severe wear transition were found, i.e., breakdown of mechanically mixed layer at temperatures of 20 and 50 °C, and severe plastic deformation at temperatures of 100–250 °C. …”
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597
Techniques for the detection and management of freezing of gait in Parkinson's disease – A systematic review and future perspectives
Published 2023-01-01“…Freezing of Gait (FoG) is one of the most critical debilitating motor symptoms of advanced Parkinson's disease (PD) with a higher rate of occurrence in aged people. …”
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598
Characterization of laser-induced plasmas as a complement to high-explosive large-scale detonations
Published 2017-09-01“…Spectral signatures and derived physical parameters following laser ablation of aluminum, graphite and laser-sparked air are examined as they relate to those observed following detonation of high explosives and as they relate to shocked air. Laser-induced breakdown spectroscopy (LIBS) reliably correlates reactions involving atomic Al and aluminum monoxide (AlO) with respect to both emission spectra and temperatures, as compared to small- and large-scale high-explosive detonations. …”
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599
The Impact of Carbohydrate Management on Coleoptile Elongation in Anaerobically Germinating Seeds of Rice (<i>Oryza sativa</i> L.) under Light and Dark Cycles
Published 2023-04-01“…Interestingly, even in intolerant lines, dramatic starch breakdown and soluble carbohydrate accumulation occurred under oxygen limitation. …”
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600
Pharmacists’ Perceptions on Safety Alerts of the Drug Utilization Review (DUR) in Electronic Health Records in a Tertiary Healthcare Hospital
Published 2023-07-01“…At the same time, 75% raised concern about the need for backup for any server breakdown. Positive perceptions about DUR lead to changing the prescription in response to an alert. …”
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