Bisphosphonates: mode of action and pharmacology. by Russell, R

“…Bisphosphonates are structural analogues of inorganic pyrophosphate but are resistant to enzymatic and chemical breakdown. Bisphosphonates inhibit bone resorption by selective adsorption to mineral surfaces and subsequent internalization by bone-resorbing osteoclasts where they interfere with various biochemical processes. …”

Harry A. Williams beyond Soundings: finding God through self-awareness and doubt by Krejčí, KT

“…</p> <p>As a homosexual priest initially suppressing his sexual orientation, Williams suffered a mental breakdown which triggered feelings of profound guilt, disapproval and mental paralysis. …”

Non-equilibrium dynamics of reaction-diffusion systems by Howard, M, Howard, Martin

“…Below a certain upper critical dimension <em>d_c</em> , this effect results in the breakdown of traditional approaches, such as mean field rate equations. …”

The fragments of impegno : interpretations of commitment in contemporary Italian narrative, 1980-1995 by Burns, J

“…In the six chapters of the main body of my thesis, I consider the further breakdown, in the recent climate of political diffidence, of the traditional sense of commitment to a specific cause, into a fragmentary exposure of a variety of 'minority' issues in the work of individual authors or groups of the 1980s and early 1990s, broadly classifiable under the 'giovani narratori' label. …”

Fabrication Of Cooling Jig Using Electro Discharge Machining (Edm) by Senin, Azman

“…A higher breakdown of equipments will affect the delivery to next processes and uncertain level of quality. …”
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Minimizing variation order on construction project due to design change by Hamdan, Hazrin

“…Based on the above analysis, the results shows that the most significant causes of variation order are design faulty/wrong technical data; duration for design phase too short; and communication breakdown & lack of coordination among consultants. …”
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Analysis of the BEAVRS PWR benchmark using SCALE and PARCS by Darnowski Piotr, Pawluczyk Michał

“…The first fuel cycle was simulated, and acceptable agreement with boron letdown curve and measurements were obtained. Finally, conclusions and recommendations for future research were presented.…”
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Good Guy or Bad Guy? The Duality of Wild-Type p53 in Hormone-Dependent Breast Cancer Origin, Treatment, and Recurrence by Eileen M. McGowan, Yiguang Lin, Diana Hatoum

“…&ldquo;Lactation is at one point perilously near becoming a cancerous process if it is at all arrested&rdquo;, Beatson, 1896. Most breast cancers arise from the milk-producing cells that are characterized by aberrant cellular, molecular, and epigenetic translation. …”
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Effects of Glass Transition and Structural Relaxation on Crystal Nucleation: Theoretical Description and Model Analysis by Jürn W. P. Schmelzer, Timur V. Tropin, Vladimir M. Fokin, Alexander S. Abyzov, Edgar D. Zanotto

“…As one of its applications, this theoretical treatment provides a new tool for the explanation of the low-temperature anomaly in nucleation in silicate and polymer glasses (the so-called “breakdown” of CNT at temperatures below the temperature of the maximum steady-state nucleation rate). …”
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The cambridge handbook of biolinguistics (cambridge handbooks in language and linguistics) / by Boeckx, Cedric, Grohmann, Kleanthes K.

Defining Coral Bleaching as a Microbial Dysbiosis within the Coral Holobiont by Aurélie Boilard, Caroline E. Dubé, Cécile Gruet, Alexandre Mercière, Alejandra Hernandez-Agreda, Nicolas Derome

“…The heat-induced breakdown of the symbiosis between the host and its dinoflagellate algae (that is, “bleaching”), is one of the most devastating outcomes for reef ecosystems. …”
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Numerical Study on Vortical Flow Structure and Performance Enhancement of Centrifugal Compressor Impeller by Seongbin Hong, Jophous Mugabi, Jae-Ho Jeong

“…At 60% of the design flow rate, a vortex breakdown occurred at the tip leakage vortex near the leading edge of the main blade, and a reverse flow at 50% chord length of the main blade’s suction surface. …”
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Tracking electricity losses and their perceived causes using nighttime light and social media by Samuel W. Kerber, Nicholas A. Duncan, Guillaume F. L’Her, Morgan Bazilian, Chris Elvidge, Mark R. Deinert

“…Summary: Urban environments are intricate systems where the breakdown of critical infrastructure can impact both the economic and social well-being of communities. …”
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RELIABILITY ANALYSIS OF FULL-FACE TUNNEL BORING MACHINES WITH THE MONTE CARLO SIMULATION TECHNIQUE by Reza Mikaeil, Hasel Amini Khoshalan, Mohammad Hossein Nasrollahi, Akbar Esmaeilzadeh

“…Reliability analysis is a practical method based on studying the behaviour of breakdowns and maintenance of machines and systems. …”
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A Cross-Country European Efficiency Measurement of Maritime Transport: A Data Envelopment Analysis Approach by Phi-Hung Nguyen, Thi-Ly Nguyen, Thi-Giang Nguyen, Duc-Thinh Nguyen, Thi-Hoai Tran, Hong-Cham Le, Huong-Thuy Phung

“…In transportation management, efficiency is critical for verifying performance and proposing the best countermeasure to meet predetermined goals. …”
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Two Types of Wear Mechanisms Governing Transition between Mild and Severe Wear in Ti-6Al-4V Alloy during Dry Sliding at Temperatures of 20–250 °C by Danhu Du, Wenbin Zhang, Jian An

“…Two types of wear mechanisms that dominated mild-severe wear transition were found, i.e., breakdown of mechanically mixed layer at temperatures of 20 and 50 °C, and severe plastic deformation at temperatures of 100–250 °C. …”
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Techniques for the detection and management of freezing of gait in Parkinson's disease – A systematic review and future perspectives by Sunil Kumar Bansal, Bijit Basumatary, Rajinder Bansal, Ashish Kumar Sahani

“…Freezing of Gait (FoG) is one of the most critical debilitating motor symptoms of advanced Parkinson's disease (PD) with a higher rate of occurrence in aged people. …”
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Characterization of laser-induced plasmas as a complement to high-explosive large-scale detonations by Clare Kimblin, Rusty Trainham, Gene A. Capelle, Xianglei Mao, Richard E. Russo

“…Spectral signatures and derived physical parameters following laser ablation of aluminum, graphite and laser-sparked air are examined as they relate to those observed following detonation of high explosives and as they relate to shocked air. Laser-induced breakdown spectroscopy (LIBS) reliably correlates reactions involving atomic Al and aluminum monoxide (AlO) with respect to both emission spectra and temperatures, as compared to small- and large-scale high-explosive detonations. …”
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The Impact of Carbohydrate Management on Coleoptile Elongation in Anaerobically Germinating Seeds of Rice (<i>Oryza sativa</i> L.) under Light and Dark Cycles by Haru Hirano, Takeru Watanabe, Mika Fukuda, Takeshi Fukao

“…Interestingly, even in intolerant lines, dramatic starch breakdown and soluble carbohydrate accumulation occurred under oxygen limitation. …”
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Pharmacists’ Perceptions on Safety Alerts of the Drug Utilization Review (DUR) in Electronic Health Records in a Tertiary Healthcare Hospital by Nouf Alshehri, Abdullah Alanazi

“…At the same time, 75% raised concern about the need for backup for any server breakdown. Positive perceptions about DUR lead to changing the prescription in response to an alert. …”
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