Cancer stem cells in immunoregulation and bypassing anti-checkpoint therapy by Elnaz Rouzbahani, Jamal Majidpoor, Sajad Najafi, Keywan Mortezaee

“…Targeting CSCs is, in fact, a key step in effective tumor breakdown and reducing tumor recurrence after immunotherapy. …”
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T-Lymphocyte Interactions with the Neurovascular Unit: Implications in Intracerebral Hemorrhage by Samuel X. Shi, Samuel J. Vodovoz, Yuwen Xiu, Ning Liu, Yinghua Jiang, Prasad V. G. Katakam, Gregory Bix, Aaron S. Dumont, Xiaoying Wang

“…In ICH, the damaged NVU precipitates the emergence and evolution of perihematomal edema as well as the breakdown of the blood–brain barrier structural coherence and function, which are critical facets during secondary ICH injury. …”
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Toughness behavior and deformation mechanisms in FCC-based Fe45Co30Cr10V10Ni5-xMnx high-entropy alloys: Insights from instrumented Charpy impact tests by Yong Hee Jo, Yeon Taek Choi, Dong Geun Kim, Jeongho Han, Sukjin Lee

“…Ductile-dimpled rupture mode in all alloys and test temperatures complicated precise explanations on Charpy impact energy, but the instrumented Charpy test provided a breakdown of total energy (ET) into initiation energy (EI) and propagation energy (EP), offering critical insights into Mn-content- and temperature-related energy variations. …”
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Reliability study of copper wire bonding and through silicon via by Chan, Marvin Jiawei

“…The influence on the presence of Cu on the leakage current conduction mechanism and time dependent dielectric breakdown (TDDB) is discussed.…”
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Common property resource management in India by Arnold, J, Stewart, W

“…</p> <p>The strong thrust towards bringing use of common resources under private or government control has often been based on a thesis which confuses degradation due to unregulated use under an open access situation for breakdown in CPR management arrangements. This misunderstanding has been compounded by a tendency to overlook reasons why the alternatives of private or state control may themselves not be sustainable or efficient, and the bias that can exist in property legislation in favour of private property.…”

Magnetic quantum oscillations in organic metals based on the molecule Bis(ethylenedithio)tetrathiafulvalene by Caulfield, J

“…The observation of SdH and magnetic breakdown oscillations has allowed the pressure dependences of the Fermi surface topology and effective masses to be deduced and compared with simultaneous measurements of the superconducting critical temperature. …”

Identification of Peat Profile, Physicochemical Properties and Microstructures on Different Peat Soil Vegetation Types by Nurul Irah Fazirah Sapar, Siti Jahara Matlan, Rohaya Alias, Aniza Ibrahim

“…As a result, understanding the peat's characteristics is critical. To investigate the characteristics of several peats in Sabah is the purpose of this study. …”
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Statistical data preprocessing methods in distance functions to enhance k-means clustering algorithm by Dalatu, Paul Inuwa

“…The Standardized Euclidean distance which uses standard deviation to down weight maximum points of the ith features on the distance clusters are being criticized in the literature by many researchers that the method is prone to outliers and has 0% breakdown points. …”
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Parenting interventions to support parent/child attachment and psychosocial adjustment in foster and adoptive parents and children: A systematic review by Nina T. Dalgaard, Trine Filges, Bjørn C. A. Viinholt, Maiken Pontoppidan

“…This further emphasises the need for future longitudinal research in prevention of placement breakdown.…”
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A plasma membrane template for macropinocytic cups by Douwe M Veltman, Thomas D Williams, Gareth Bloomfield, Bi-Chang Chen, Eric Betzig, Robert H Insall, Robert R Kay

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Rule of Law and Democracy: countermajority balance against authoritarian effects of polarization by Ricardo Rivero Ortega

“…Democracy and rule of law are complementary constitutional principles, not possible separately.   Constructive criticism of its shortcomings is acceptable, but the affirmation of its failure threatens the legitimacy of essential institutions for social coexistence. …”
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The Expression Pattern of Insulin-Like Growth Factor Subtype 3 (igf3) in the Orange-Spotted Grouper <i>Epinephelus coioides</i> and Its Function on Ovary Maturation by Fang Jiao, Bing Fu, Yan Yang, Huayi Xue, Yuanyuan Wu, Huihong Zhao, Qing Wang, Huirong Yang

“…Meanwhile, Igf3 increased germinal-vesicle breakdown in a time- and dose-dependent manner. In vitro, treatment of primary ovarian cells with Igf3 up-regulated significantly the mRNA expression level of genes related to sex determination and reproduction such as forkhead boxl2 (<i>foxl2</i>), dosage-sensitive sex reversal adrenal hypoplasia critical region on chromosome x gene 1 (<i>dax1</i>), cytochrome P450 family 19 subfamily member 1 a (<i>cyp19a1a</i>), cytochrome P450 family 11 subfamily a member 1 a (<i>cyp11a1a</i>) and luteinizing hormone receptor 1 (<i>lhr1</i>). …”
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Intermittent Fasting Reduces Neuroinflammation and Cognitive Impairment in High-Fat Diet-Fed Mice by Downregulating Lipocalin-2 and Galectin-3 by Jaewoong Lee, Hyeong Seok An, Hyun Joo Shin, Hye Min Jang, Chae Oh Im, Yeonjun Jeong, Kibaek Eum, Sejeong Yoon, So Jeong Lee, Eun Ae Jeong, Kyung Eun Kim, Gu Seob Roh

“…IF also improved HFD-induced memory deficits by inhibiting blood–brain barrier breakdown and neuroinflammation. Furthermore, immunofluorescence showed that IF reduced HFD-induced astrocytic LCN2 and microglial GAL3 protein expression in the hippocampus of HFD mice. …”
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Sphingomyelin Depletion Inhibits CXCR4 Dynamics and CXCL12-Mediated Directed Cell Migration in Human T Cells by Sofía R. Gardeta, Eva M. García-Cuesta, Gianluca D’Agostino, Blanca Soler Palacios, Adriana Quijada-Freire, Pilar Lucas, Jorge Bernardino de la Serna, Jorge Bernardino de la Serna, Jorge Bernardino de la Serna, Carolina Gonzalez-Riano, Coral Barbas, José Miguel Rodríguez-Frade, Mario Mellado

“…Prolonged treatment of T cells with bacterial sphingomyelinase promoted the complete and sustained breakdown of sphingomyelins and the accumulation of the corresponding ceramides, which altered both membrane fluidity and CXCR4 nanoclustering and dynamics. …”
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Macrophage colony-stimulating factor (M-CSF) is an intermediate in the process of luteinizing hormone-induced decrease in natriuretic peptide receptor 2 (NPR2) and resumption of oo... by Wenchao Sun, Chang Liu, Ying Feng, Guangchao Zhuo, Wenjing Zhou, Xiaoyang Fei, Zhifen Zhang

“…The presence of germinal vesicle breakdown (GVBD) was examined under a stereomicroscope to morphologically evaluate resumption of oocyte meiosis. …”
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Therapeutic Properties of Ayahuasca Components in Ischemia/Reperfusion Injury of the Eye by Anna Szilágyi, Barbara Takács, Réka Szekeres, Vera Tarjányi, Mariann Bombicz, Dániel Priksz, Attila Kovács, Béla Juhász, Ede Frecska, Zoltán Szilvássy, Balázs Varga

“…To inhibit its rapid breakdown by monoamine-oxidase A (MAO-A) enzyme, DMT was co-administered with harmaline, a β-carboline in the Amazonian Ayahuasca brew. …”
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Academy for Quality and Safety Improvement (AQSI) project to improve diagnosis and documentation of malnutrition in a community hospital by Om Parkash, Saad Jamil, Valarie Chudzinski, Nayha Tahir, Shrey Gole, Jacqueline Deleon, Cindy Forde, Farah Zahra

“…There is a clear link between malnutrition, increased length of hospital stay, higher risk of readmissions and infections, skin breakdown, and higher hospital costs due to complications.Methods We conducted a quality improvement project to increase the number of times patients were accurately diagnosed and successfully coded as malnourished. …”
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Status of Aluminum Oxide Gate Dielectric Technology for Insulated-Gate GaN-Based Devices by Anthony Calzolaro, Thomas Mikolajick, Andre Wachowiak

“…In this regard, the minimization of trap states is of critical importance to the advent of different insulated-gate GaN-based devices. …”
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β1 integrin is essential for blood–brain barrier integrity under stable and vascular remodelling conditions; effects differ with age by Sebok K. Halder, Violaine D. Delorme-Walker, Richard Milner

“…While extracellular matrix-integrin interactions play critical roles in regulating the balance between vascular stability and remodeling, it remains to be established whether manipulation of integrin function weakens or strengthens vascular integrity. …”
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Detoxification and catabolism of mesotrione and fomesafen facilitated by a Phase II reaction acetyltransferase in rice by Zhao Jie Chen, Xiao Yan Zhai, Jintong Liu, Nan Zhang, Hong Yang

“…Conclusions: These results signified that OsACE1 expression is required for detoxifying the two poisoning chemicals in rice and plays a critical role in accelerating breakdown of the pesticides mainly through Phase II reaction mechanism pathways.…”
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