IRF1 governs the expression of SMARCC1 via the GCN5-SETD2 axis and actively engages in the advancement of osteoarthritis by Dong Wang, Yujun Zhang, Liangping Zhang, Du He, Lan Zhao, Zhimin Miao, Wei Cheng, Chengyue Zhu, Li Zhu, Wei Zhang, Hongting Jin, Hang Zhu, Hao Pan

“…Background: Osteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of joint cartilage and underlying bone. Macrophages are a type of white blood cell that plays a critical role in the immune system and can be found in various tissues, including joints. …”
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INTEGRATING TECHNOLOGY AND DIGITAL CONNECTIVITY IN SERVICE RECOVERY STRATEGIES TO ACHIEVE RECOVERY SATISFACTION DURING THE COVID-19 PANDEMIC: A HYBRID APPROACH by Steven Kayambazinthu Msosa

“…The main problems customers face are service failures and breakdowns. As a result, customers are grappling with how they can have their problems addressed during the pandemic. …”
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Research Progress on the Wear Resistance of Key Components in Agricultural Machinery by Ying Wang, Dong Li, Cheng Nie, Pan Gong, Junsheng Yang, Zhigang Hu, Bin Li, Ming Ma

“…However, wear and tear are inevitable when using agricultural machinery. The failure of critical wear-resistant parts is responsible for over 50% of rural machinery breakdowns. …”
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Use of 3-dimensional printing at the point-of-care to manage a complex wound in hemifacial necrotizing fasciitis: a case report by Sarah C. Nyirjesy, Ryan T. Judd, Yazen Alfayez, Peter Lancione, Brian Swendseid, Natalia von Windheim, Stephen Nogan, Nolan B. Seim, Kyle K. VanKoevering

“…After multiple debridements, she remained critically ill with poor vascularity of tissue in the wound bed and no evidence of healthy granulation tissue and concern for additional breakdown towards the right orbit, mediastinum, and pretracheal soft tissues, precluding tracheostomy placement despite prolonged intubation. …”
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Partial discharge detection and identification based on chipless RFID system by Yang, Zhenning

“…High voltage (HV) and medium voltage (MV) electrical assets, such as generators, transformers, and switchgears, are parts of critical power generation and transmission infrastructures for the power distribution system. …”
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Dynamic Job and Conveyor-Based Transport Joint Scheduling in Flexible Manufacturing Systems by Sebastiano Gaiardelli, Damiano Carra, Stefano Spellini, Franco Fummi

“…Efficiently managing resource utilization is critical in manufacturing systems to optimize production efficiency, especially in dynamic environments where jobs continually enter the system and machine breakdowns are potential occurrences. …”
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Thermal Analysis of Low-Power Three-Phase Induction Motors Operating under Voltage Unbalance and Inter-Turn Short Circuit Faults by Amel Adouni, Antonio J. Marques Cardoso

“…Therefore, induction motor faults are not only the cause of users’ frustrations but they also drive up the costs related to unexpected breakdowns, repair actions, and safety issues. One of the most critical faults in three-phase induction motors is related to the occurrence of inter-turn short circuits, due to its devastating consequences. …”
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FPGA implementation of an improved envelope detection approach for bearing fault diagnosis by Mohamed Rebiai, Billel Bengharbia, Mohamed Maazouz, Yassine Toumi

“…Bearing faults frequently result in machinery breakdowns, incurring substantial downtime and maintenance expenses. …”
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A hybrid ensemble learning approach for the aging-dependent reliability prediction of power transformers by Wei Huang, Yue Sun, Yanghan Zhou, Xin Cheng, Zixin Xiang, Changzheng Shao, Bo Hu, Kaigui Xie

“…As the most critical equipment for electricity transmission, power transformers (PTs) generally have irreversible insulating degradation, which makes them susceptible to aging breakdowns. …”
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Mixed Reality Human–Robot Interface With Adaptive Communications Congestion Control for the Teleoperation of Mobile Redundant Manipulators in Hazardous Environments by Krzysztof Adam Szczurek, Raul Marin Prades, Eloise Matheson, Jose Rodriguez-Nogueira, Mario Di Castro

“…Communication issues can lead to critical consequences, such as imprecise manipulation resulting in collisions, breakdowns and mission failures. …”
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An Embedded Machine Learning Fault Detection System for Electric Fan Drive by Khin Htet Htet Aung, Chiang Liang Kok, Yit Yan Koh, Tee Hui Teo

“…Industrial fans are critical components in industrial production, where unexpected damage of important fans can cause serious disruptions and economic costs. …”
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COGNITIVE AND ERGONOMIC ASPECTS HUMAN INTERACTIONS WITH A COMPUTER by Галина Валеріївна Мигаль, Валерій Павлович Мигаль

“…Their combination can lead to unpredictable technical failures and psychophysiological breakdowns, as well as to systemic management problems. …”
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A systematic approach for architecture-level energy estimation of accelerator designs by Wu, Yannan(Data scientist)Massachusetts Institute of Technology.

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Development and Practical Implementation of Digital Observer for Elastic Torque of Rolling Mill Electromechanical System by Vadim R. Gasiyarov, Andrey A. Radionov, Boris M. Loginov, Alexander S. Karandaev, Olga A. Gasiyarova, Vadim R. Khramshin

“…Long experimental research proved the efficiency of dynamic load monitoring and the reduction in the number of equipment breakdowns.…”
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Pathogenic and Therapeutic Relevance of JAK/STAT Signaling in Systemic Lupus Erythematosus: Integration of Distinct Inflammatory Pathways and the Prospect of Their Inhibition with... by Alessia Alunno, Ivan Padjen, Antonis Fanouriakis, Dimitrios T. Boumpas

“…Breakdowns of this system and/or increased signal transduction may lead to autoimmunity and other diseases. …”
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Letter From the Editor by Regina Hoffman

“…In this issue we also include a very timely original article that discusses process breakdowns that can lead to failure to recognize, treat, and prevent the spread of respiratory infections. …”
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Microdéconnexions : discontinuités et ruptures du contact communicationnel. Entretien avec Laurence Allard et Edgar Mbanza by Camille Paloque-Bergès, Laurence Allard, Edgar Mbanza

“…We invited two sociologists of uses and communication, Laurence Allard and Edgar Mbanza, who, through their interest in practices, have had to deal very concretely with these breakdowns in communication –micro-disconnections– in their fields. …”
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Winding Tensor Approach for the Analytical Computation of the Inductance Matrix in Eccentric Induction Machines by Javier Martinez-Roman, Ruben Puche-Panadero, Angel Sapena-Bano, Manuel Pineda-Sanchez, Juan Perez-Cruz, Martin Riera-Guasp

“…Induction machines (IMs) are critical components of many industrial processes, what justifies the use of condition-based maintenance (CBM) systems for detecting their faults at an early stage, in order to avoid costly breakdowns of production lines. …”
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Auditory Verb Generation Performance Patterns Dissociate Variants of Primary Progressive Aphasia by Sladjana Lukic, Sladjana Lukic, Abigail E. Licata, Abigail E. Licata, Elizabeth Weis, Rian Bogley, Rian Bogley, Buddhika Ratnasiri, Ariane E. Welch, Leighton B. N. Hinkley, Z. Miller, Z. Miller, Adolfo M. Garcia, Adolfo M. Garcia, Adolfo M. Garcia, Adolfo M. Garcia, John F. Houde, Srikantan S. Nagarajan, Maria Luisa Gorno-Tempini, Maria Luisa Gorno-Tempini, Valentina Borghesani, Valentina Borghesani

“…Taken together, our findings indicate that error patterns in an auditory verb generation task are associated with the breakdown of different neurocognitive mechanisms across PPA variants. …”
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Explainable Predictive Maintenance of Rotating Machines Using LIME, SHAP, PDP, ICE by Shreyas Gawde, Shruti Patil, Satish Kumar, Pooja Kamat, Ketan Kotecha, Sultan Alfarhood

“…Rotating machines are critical components in manufacturing industries. In the vast world of Industry 4.0, where an IoT network acts as a monitoring and decision-making system, predictive maintenance is quickly gaining importance. …”
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