Fragment screening for stabilizers and binders to human DJ-1 由 Oh, Xu Xuan

“...ThermoFluor assay (DSF) is used to screen the fragment libraries where five ligands namely CPD1, CPD2, CPD3, CPD4 and CPD5 were identified to confer stability to DJ1. The assays were performed under control conditions and oxidative conditions from 0x to 20x hydrogen peroxide (H2O2) molarity in excess. ...”
获取全文

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson’s Disease 由 Jihoon Jang, Soyeon Jeong, Sung Ik Lee, Wongi Seol, Hyemyung Seo, Ilhong Son, Dong Hwan Ho

“...We speculate that OxiDJ-1 levels in PD patient urine might be higher than that in non-PD controls. ...”
获取全文

DJ-1 as a Novel Therapeutic Target for Mitigating Myocardial Ischemia–Reperfusion Injury 由 Jia-Bin Zhou, Tian-Peng Wei, Dan Wu, Feng Zhou, Ru-Xing Wang

“...This underscores the need to develop new methods to protect the heart from damage. DJ-1 is a multifunctional intracellular protein encoded by the PARK7 gene that plays roles in processes including the control of autophagy, the preservation of mitochondrial integrity, the prevention of apoptosis, and the elimination of oxidative stress. ...”
获取全文

Inhibitors of lysosomal function or serum starvation in control or LAMP2 deficient cells do not modify the cellular levels of Parkinson disease-associated DJ-1/PARK 7 protein. 由 Raúl Sánchez-Lanzas, José G Castaño

“...We have used several cell lines with disrupted LAMP2 gene expression and their respective control cells to test the possible role of lysosomal degradation and in particular CMA in DJ-1 /PARK7 degradation. ...”
获取全文

A German DJ, Postmodern Dreams, and the Ambivalent Politics of East–West Exchange at the First Exhibition of Approximate Art in Riga, April 1987 由 Kevin C. Karnes

“...Mining archival sources in Berlin and Riga, this article reconstructs the complicated path by which the DJ came to perform at the event. It reveals a surprising network of relations and alliances operating in tandem behind the scenes, featuring a Riga artist dedicated to enacting a vision of postmodern performance in his city, an ambitiously networking émigré Latvian living in exile in West Germany, and a pair of Soviet offices under direct control of the KGB, charged with managing cultural exchanges with the West in hopes of currying sympathies for Soviet culture and policy. ...”
获取全文

Generation of controllable magnetic stimuli 由 Denison, T, Rogers, DJ, Memarian Sorkhabi, M

Further considerations for placebo controls in surgical trials 由 Campbell, MK, Beard, DJ, Blazeby, JM, Cousins, S

Loyalists, localists, and legibility: the calibrated control of provincial leadership teams in China 由 Bulman, DJ, Jaros, K

Emergency treatment of obstructive pyelonephritis: A single center series 由 Bulent Kati, Eser Ordek, Omer Madsar, Eyyup Sabri Pelit

“...Objective: This study aims to compare two different drainage methods, percutaneous nephrostomy (PCN) and retrograde ureteral double-J (DJ) stent insertion, in patients with obstructive pyelonephritis (OP). ...”
获取全文

Optimal Control of Collective Electrotaxis in Epithelial Monolayers 由 Martina-Perez, SF, Breinyn, IB, Cohen, DJ, Baker, RE

Switchable, reagent-controlled diastereodivergent photocatalytic carbocyclisation of imine-derived α-amino radicals 由 Maitland, JAP, Leitch, JA, Yamazaki, K, Christensen, KE, Cassar, DJ, Hamlin, TA, Dixon, DJ

Implications of vertical stability control on the SPARC tokamak 由 A.O. Nelson, D.T. Garnier, D.J. Battaglia, C. Paz-Soldan, I. Stewart, M. Reinke, A.J. Creely, J. Wai

获取全文

Cash transfers to enhance TB control: lessons from the HIV response 由 Rudgard, WE, Carter, DJ, Scuffell, J, Cluver, LD, Fraser-Hurt, N, Boccia, D

Control Predictivo Distribuido Óptimo Aplicado al Control de Nivel de un Proceso de Cuatro Tanques Acoplados 由 Felipe D.J. Sorcia-Vázquez, Carlos D. Garcia-Beltran, Guillermo Valencia-Palomo, Gerardo Guerrero-Ramírez, Manuel Adam-Medina, Ricardo Escobar-Jiménez

获取全文

Severe maternal sepsis in the UK, 2011–2012: A national case-control study 由 Acosta, CD, Kurinczuk, JJ, Lucas, DN, Tuffnell, DJ, Sellers, S, Knight, M

Prevalence and determinants of hypertension control among almost 100 000 treated adults in the UK 由 Tapela, N, Collister, J, Clifton, L, Turnbull, I, Rahimi, K, Hunter, DJ

Distributed Model Predictive Control Applied to a Four Interconnected Tank Process 由 Felipe D.J. Sorcia Vázquez, Carlos D. García Beltrán, Guillermo Valencia Palomo, Gerardo Guerrero Ramírez, Manuel Adam Medina, Ricardo Escobar Jiménez

获取全文

Optimizing the design of invasive placebo interventions in randomized controlled trials 由 Cousins, S, Blencowe, NS, Tsang, C, Chalmers, K, Mardanpour, A, Carr, AJ, Campbell, MK, Cook, JA, Beard, DJ, Blazeby, JM

Fine-tuned photochromic sulfonylureas for optical control of beta cell Ca2+ fluxes 由 Rückert, A-K, Ast, J, Hasib, A, Nasteska, D, Viloria, K, Broichhagen, J, Hodson, DJ

Application of a convolutional neural network to the quality control of MRI defacing 由 Delbarre, DJ, Santos, L, Ganjgahi, H, Horner, N, McCoy, A, Westerberg, H, Häring, DA, Nichols, TE, Mallon, A-M