Hypermethylation Status of Promoter is an Epigenetic Change in Lymphoied Malignancies by Gholamreza Khamisipour, Najmaldin Saki, Majid Farshdousti Hagh

“…Of 39 genes 23 genes showed hypermethylation status in promoter region of genes including: SMC1L2, NES1, ADAMTS1, PGR, sFRP1, CDH1, ADAMTS5, CDH13, LATS1, DKK3, WIF1, LATS2, REPRIMO, sFRP5, PARK2, PACRG, HDPR1, RIZ, APAF1, ARTS, ASPP1, DIABLO and sFRP4.(8) Dunwell et al. demonstrated frequent epigenetic inactivation of THRB, BNC1, PPP2R3A, FBLN2 and MSX1 in lymphoied malignancies including B-cell and T-cell ALL.(9) The recognition of hypermethylated genes in lymphoid malignancies showing epigenetic alterations will be useful in developing targeted epigenetic therapies.(10, 11, 12) Also, Methylation changes of CpG islands in promoter region of the p57KIP2, p73, and p15 genes have been shown to have poor prognostic value in adult ALL patients with Philadelphia (Ph) chromosome-negative disease.(13) These methylation changes are stable in greater number of patients with ALL at the time of relapse. …”
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Salar de Infieles (25°S-69°O): ocupaciones alfareras, arte rupestre e interrelaciones culturales de un asentamiento de las tierras altas, Región de Atacama, Chile by Carlos González Godoy, Patricio López Mendoza, Consuelo Carracedo, Carlos Carrasco, Elvira Latorre, Rodrigo Loyola, Pablo Díaz-Jarufe, Carmen Castells, Víctor Méndez, Daniel Varas, Vanessa Orrego

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Dinámica poblacional del pez invasor del género Pterygoplichthys en la cuenca de Chacalapa (cuenca de Coatzacoalcos) Veracruz, México by Guadalupe Castillo Capitán, Zeferino Cruz León, César Gabriel Meiners Mandujano, Ángel Héctor Hernández Romero, Nereida Rodríguez Orozco

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A Process for Evaluating Adverse Environmental Impacts by Cooling-Water System Entrainment at a California Power Plant by C.P. Ehrler, J.R. Steinbeck, E.A. Laman, J.B. Hedgepeth, J.R. Skalski, D.L. Mayer

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Salar de Infieles (25°S-69°O): ocupaciones alfareras, arte rupestre e interrelaciones culturales de un asentamiento de las tierras altas, Región de Atacama, Chile by Carlos González Godoy, Patricio López Mendoza, Consuelo Carracedo, Carlos Carrasco, Elvira Latorre, Rodrigo Loyola, Pablo Díaz-Jarufe, Carmen Castells, Víctor Méndez, Daniel Varas, Vanessa Orrego

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Comparison of a ready-to-use liquid glucagon injection administered by autoinjector to glucagon emergency kit for the symptomatic relief of severe hypoglycemia: two randomized cros... by Anh Nguyen, Mark P Christiansen, Martin Cummins, Steven Prestrelski, Nicole C Close, Khaled Junaidi

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The ‘ForensOMICS’ approach for postmortem interval estimation from human bone by integrating metabolomics, lipidomics, and proteomics by Andrea Bonicelli, Hayley L Mickleburgh, Alberto Chighine, Emanuela Locci, Daniel J Wescott, Noemi Procopio

“…Anterior midshaft tibial bone was collected from four female body donors before their placement at the Forensic Anthropology Research Facility owned by the Forensic Anthropological Center at Texas State (FACTS). …”
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Safety and immunogenicity of 15-valent pneumococcal conjugate vaccine (PCV-15) compared to PCV-13 in healthy older adults by Helen L. Stacey, Jeffrey Rosen, James T. Peterson, Angela Williams-Diaz, Vanita Gakhar, Tina M. Sterling, Camilo J. Acosta, Katrina M. Nolan, Jianing Li, Alison Pedley, Patrice Benner, Chitrananda Abeygunawardana, Michael Kosinski, William J. Smith, Hari Pujar, Luwy K. Musey

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Examining the potential causal relationships among smoking behaviors, blood DNA methylation profiles, and the development of coronary heart disease and myocardial infarction by Wenhua Li, Pan Dong, Yixiao Li, Jiaxin Tang, Siyang Liu, Ling Tu, Xizhen Xu

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Volatilomics of raspberry fruit germplasm by combining chromatographic and direct-injection mass spectrometric techniques by Brian Farneti, Iuliia Khomenko, Matteo Ajelli, Karen Elizabeth Wells, Emanuela Betta, Eugenio Aprea, Eugenio Aprea, Lara Giongo, Franco Biasioli

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Protective Effect of Ferulic Acid against Hydrogen Peroxide Induced Apoptosis in PC12 Cells by Hironao Nakayama, Masako Nakahara, Erina Matsugi, Midori Soda, Tomoka Hattori, Koki Hara, Ayuki Usami, Chiaki Kusumoto, Shigeki Higashiyama, Kiyoyuki Kitaichi

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Case report: Long-term follow-up of patients who received a FimCH vaccine for prevention of recurrent urinary tract infections caused by antibiotic resistant Enterobacteriaceae: a... by Elise Perer, Helen Stacey, Terri Eichorn, Heidi Hughey, Julie Lawrence, Eric Cunningham, Mark O’Neil Johnson, Kevin Bacon, Andrew Kau, Scott J. Hultgren, Thomas M. Hooton, Jennifer L. Harris

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Defining Regional and Local Sediment Sources in the Ancestral Colorado River System: A Heavy Mineral Study of a Mixed Provenance Unit in the Fish Creek-Vallecito Basin, Southern Ca... by Paula McGill, Uisdean Nicholson, Dirk Frei, David Macdonald

“…The PSG consists of three coeval formations: 1) Canebrake Conglomerate, a basin margin that has coarse alluvial fan deposits derived from surrounding igneous basement; 2) Olla Formation, fan-fringe sandstones containing L-Suite, C-Suite, and mixed units; and 3) Arroyo Diablo Formation, mineralogically mature C-Suite sandstones. …”
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Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy by Shuo-Shuo Liu, Tian-Xia Jiang, Fan Bu, Ji-Lan Zhao, Guang-Fei Wang, Guo-Heng Yang, Jie-Yan Kong, Yun-Fan Qie, Pei Wen, Li-Bin Fan, Ning-Ning Li, Ning Gao, Xiao-Bo Qiu

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Drivers of plateau adaptability in cashmere goats revealed by genomic and transcriptomic analyses by Cuiling Wu, Shengchao Ma, Bingru Zhao, Chongkai Qin, Yujiang Wu, Jiang Di, Langda Suo, Xuefeng Fu

“…These PSGs showed potential relationships with various phenotypes, including myocardial development and activity (LOC106502520, ATP2A2, LOC102181869, LOC106502520, MYL2, ISL1, and LOC102181869 genes), pigmentation (MITF and KITLG genes), hair follicles/hair growth (YAP1, POGLUT1, AAK1, HES1, WNT1, PRKAA1, TNKS, WNT5A, VAX2, RSPO4, CSNK1G1, PHLPP2, CHRM2, PDGFRB, PRKAA1, MAP2K1, IRS1, LPAR1, PTEN, PRLR, IBSP, CCNE2, CHAD, ITGB7, TEK, JAK2, and FGF21 genes), and carcinogenesis (UBE2R2, PIGU, DIABLO, NOL4L, STK3, MAP4, ADGRG1, CDC25A, DSG3, LEPR, PRKAA1, IKBKB, and ABCG2 genes). …”
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Apoptin causes apoptosis in HepG‐2 cells via Ca2+ imbalance and activation of the mitochondrial apoptotic pathway by Xiaoyang Yu, Tongxing Wang, Yue Li, Yiquan Li, Bing Bai, Jinbo Fang, Jicheng Han, Shanzhi Li, Zhiru Xiu, Zirui Liu, Xia Yang, Yaru Li, Guangze Zhu, Ningyi Jin, Chao Shang, Xiao Li, Yilong Zhu

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Biological and Cellular Effects of Percutaneous Electrolysis: A Systematic Review by Jacobo Rodríguez-Sanz, Sergi Rodríguez-Rodríguez, Carlos López-de-Celis, Miguel Malo-Urriés, Soledad Pérez-Amodio, Román Pérez-Antoñanzas, Sergio Borrella-Andrés, Isabel Albarova-Corral, Miguel Ángel Mateos-Timoneda

“…A significant increase in cell death markers, such as LDH, Yo-Pro, cytochrome C, and Smac/Diablo markers, was observed during the first 7 days. …”
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High-resolution SOFIA/EXES Spectroscopy of Water Absorption Lines in the Massive Young Binary W3 IRS 5 by Jialu Li, Adwin Boogert, Andrew G. Barr, Curtis DeWitt, Maisie Rashman, David Neufeld, Nick Indriolo, Yvonne Pendleton, Edward Montiel, Matt Richter, J. E. Chiar, Alexander G. G. M. Tielens

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Profiles of subgingival microbiomes and gingival crevicular metabolic signatures in patients with amnestic mild cognitive impairment and Alzheimer’s disease by Che Qiu, Wei Zhou, Hui Shen, Jintao Wang, Ran Tang, Tao Wang, Xinyi Xie, Bo Hong, Rujing Ren, Gang Wang, Zhongchen Song

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Transcriptome Profiling Unveils the Mechanisms of Inflammation, Apoptosis, and Fibrosis in the Liver of Juvenile Largemouth Bass <i>Micropterus salmoides</i> Fed High-Starch Diets by Xifeng Liu, Hongkang Liu, Kangwei Wang, Chuanjie Qin, Yuanfa He, Li Luo, Shimei Lin, Yongjun Chen

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