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Rasgos básicos de la extracción de variscita en Palazuelo de las Cuevas (Zamora)
Published 2017-06-01Get full text
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Multi-block data integration analysis for identifying and validating targeted N-glycans as biomarkers for type II diabetes mellitus
Published 2022-06-01“…The multivariate integrative framework, DIABLO was employed for the statistical analysis. …”
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Identification of Breast Cancer Subtype-Specific Biomarkers by Integrating Copy Number Alterations and Gene Expression Profiles
Published 2021-03-01“…<i>Background and Objectives</i>: Breast cancer is a heterogeneous disease categorized into four subtypes. Previous studies have shown that copy number alterations of several genes are implicated with the development and progression of many cancers. …”
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Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells
Published 2009-12-01“…In addition, compound-K induced a series of intracellular events associated with both the mitochondrial- and death receptor-dependent apoptotic pathways, namely, (1) the activation of caspases-3, -8, and -9; (2) the loss of mitochondrial membrane potential; (3) the release of cytochrome <it>c </it>and Smac/DIABLO to the cytosol; (4) the translocation of Bid and Bax to mitochondria; and (5) the downregulations of Bcl-2 and Bcl-xL. …”
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Excessive food intake, obesity and inflammation process in Zucker fa/fa rat pancreatic islets.
Published 2011-01-01“…Despite JNK overexpression, cell viability was unaffected probably because of decreases in cleaved caspase3 as well as in SMAC/DIABLO and APP, involved in the induction and amplification of apoptosis. …”
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Bortezomib and Arsenic Trioxide Activity on a Myelodysplastic Cell Line (P39): A Gene Expression Study
Published 2015-07-01Get full text
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Bortezomib and Arsenic Trioxide Activity on a Myelodysplastic Cell Line (P39): A Gene Expression Study
Published 2015-09-01Get full text
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Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
Published 2012-01-01Get full text
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Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood
Published 2022-04-01“…The identified genomic regions were associated with genes including H19, HOXA3/HOXA4, RUNX3, BRICD5, PLXNB2, and RP13. For the single CpG sites, the strongest association was noted for cg09736286 in the DIABLO gene (OR [for 1 SD] = 2.99, 95% CI: 1.95–4.59, P-value = 4.81 × 10–7). …”
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Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment.
Published 2016-01-01“…Expression levels of Bcl-2, VDAC1, MAVS, AIF and SMAC/Diablo were markedly increased in CLL-derived lymphocytes. …”
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Una mirada diferente al suicidio durante el Siglo de las Luces
Published 2023-05-01Get full text
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