Development and Internal Validation of a Novel Nomogram Predicting the Outcome of Salvage Radiation Therapy for Biochemical Recurrence after Radical Prostatectomy in Patients witho... by Dennie Meijer, Pim J. van Leeuwen, Wietse S.C. Eppinga, Ben G.L. Vanneste, Philip Meijnen, Laurien A. Daniels, Roderick C.N. van den Bergh, Anne P. Lont, Yves J.L. Bodar, Rosemarijn H. Ettema, Katelijne C.C. de Bie, Frederik H.K. Oudshoorn, Jakko A. Nieuwenhuijzen, Henk G. van der Poel, Maarten L. Donswijk, Martijn W. Heymans, Daniela E. Oprea-Lager, Eva E. Schaake, André N. Vis

“…Methods: All 302 eligible patients undergoing PCa sRT in four reference centers between September 2015 and August 2020 were included. …”
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Exploring the utility and acceptability of Faecal immunochemical testing (FIT) as a novel intervention for the improvement of colorectal Cancer (CRC) surveillance in individuals wi... by Anne Lincoln, Sally Benton, Carolyn Piggott, Bernard V. North, Jane Rigney, Caroline Young, Philip Quirke, Peter Sasieni, Kevin J. Monahan

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Different vascular healing process between bioabsorbable polymer-coated everolimus-eluting stents versus bioresorbable vascular scaffolds via optical coherence tomography and coron... by Wan Ahmad, Wan Azman, Nakayoshi, Takaharu, Mahmood Zuhdi, Ahmad Syadi, Ismail, Muhammad Dzafir, Abidin, Imran Zainal, Ino, Yasushi, Kubo, Takashi, Akasaka, Takashi, Fukumoto, Yoshihiro, Ueno, Takafumi

Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-R... by Green, C, Scarselli, E, Voysey, M, Capone, S, Vitelli, A, Nicosia, A, Cortese, R, Thompson, A, Sande, C, de Lara, C, Klenerman, P, Pollard, A

“…RSV001 is a phase 1 (first-in-man), open-label, dose-escalation, clinical trial of novel genetic viral-vectored vaccine candidates PanAd3-RSV and modified vaccinia virus Ankara (MVA)-RSV. …”

A randomized clinical efficacy trial of Hehui capsule against hyperlipidemia by Ruiting Ma, Yuanyuan Ma, Junchan Qiao, Lixia Chen, Mingxing Hou

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Assessing, updating and utilising primary care smoking records for lung cancer screening by Grace McCutchan, Jean Engela-Volker, Philip Anyanwu, Kate Brain, Nicole Abel, Sinan Eccles

“…This study piloted a novel strategy for ascertaining smoking status in primary care and tested EHR search combinations to identify those potentially eligible for lung cancer screening. …”
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A model for rapid, active surveillance for medically-attended acute gastroenteritis within an integrated health care delivery system. by Mark A Schmidt, Holly C Groom, Allison L Naleway, Christianne Biggs, S Bianca Salas, Kayoko Shioda, Zachary Marsh, Judy L Donald, Aron J Hall

“…BACKGROUND:This study presents a novel methodology for estimating all-age, population-based incidence rates of norovirus and other pathogens that contribute to acute gastroenteritis in the United States using an integrated healthcare delivery system as a surveillance platform. …”
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Creativity, artificial intelligence, and the requirement of human authors and inventors in copyright and patent law by Mammen, CE, Collyer, M, Dolin, R, Gangjee, DS, Melham, T, Mustaklem, M, Sundaralingam, P, Wang-Maścianica, V

“…The external component refers to whether an artifact (or idea, or other thing) exhibits the qualities of being novel, valuable, and (on some accounts) surprising. …”

Prognostic Implication of Lymphovascular Invasion in Early Gastric Cancer Meeting Endoscopic Submucosal Dissection Criteria: Insights from Radical Surgery Outcomes by Bo Sun, Huanhuan Li, Xiaodong Gu, Hong Cai

“…Future research should explore the potential incorporation of LVI status into existing TNM staging systems and novel therapeutic strategies.…”
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Digital self-report instruments for repeated measurement of mental health in the general adult population: a protocol for a systematic review by Greg Murray, Zhao Hui Koh, Jason Skues

“…This review is a precursor to developing a novel future integrated digital instrument for repeated measurements. …”
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Characteristics and Barriers of Emergency Department Patients Overdue for Cancer Screening by Sara W. Heinert, Mohammed Ahmed, Kelvin Guzman-Baez, Ananya Penugonda, Sarah Oh, Affan Aamir, Jeanne M. Ferrante

“…Emergency departments (ED) may be a novel place for cancer screening education for underserved patients. …”
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Monitoring the safety of COVID-19 vaccines in pregnancy in the US by Pedro L. Moro, Lakshmi Panagiotakopoulos, Titilope Oduyebo, Christine K. Olson, Tanya Myers

“…The Vaccine Adverse Event Reporting System is a national, passive system that captures reports of potential adverse events. V-safe is a novel, active system that uses text messaging and web-based surveys to provide health check-ins after vaccination; and enrolls eligible v-safe participants in the v-safe pregnancy registry. …”
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Is an individually tailored programme of intense leg resistance and dynamic exercise acceptable to adults with an acute lateral patellar dislocation? A feasibility study by Forde, C, Haddad, M, Hirani, SP, Keene, D

“…<br><strong> Results<br></strong> Fifteen of 22 (68%) patients with a lateral patellar dislocation were eligible. All eligible (100%) were recruited. Two of 15 (13%) participants provided no outcome data, 2/15 (13%) provided partial outcome data, and 11/15 (73%) provided all outcome data. …”

Circ-SHPRH in human cancers: a systematic review and meta-analysis by Hong Xiong, Gaozhen Huang, Yi Zhu, Ruiqi Chen, Ling Zuo, Hongwei Liu

“…Eighteen research papers were included in this review, and 11 papers were selected for meta-analysis after screening. Three eligible published studies about circ-SHPRH were enrolled based on their tumor diagnosis aspect, 7 eligible published studies were related to overall survival (OS), and 3 eligible published studies were related to tumor grade. …”
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Preventive treatment patterns and treatment satisfaction in migraine: results of the OVERCOME (EU) study by Julio Pascual, Tommaso Panni, Grazia Dell’Agnello, Saygin Gonderten, Diego Novick, Stefan Evers

“…Abstract Background Insights into the burden, needs and treatment of migraine from internet-based surveys in diverse real-world migraine populations are needed, especially at a time when novel preventive migraine medications are becoming part of the therapeutic armamentarium. …”
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Implementation of Glucose-6-Phosphate Dehydrogenase (G6PD) testing for Plasmodium vivax case management, a mixed method study from Cambodia by Cassidy-Seyoum, SA, Chheng, K, Chanpheakdey, P, Meershoek, A, Hsiang, MS, von Seidlein, L, Tripura, R, Adhikari, B, Ley, B, Price, RN, Lek, D, Engel, N, Thriemer, K

“…The STANDARD G6PD test (Biosensor) is a novel point-of-care diagnostic capable of identifying G6PD deficiency prior to treatment. …”

Influence of age on knee replacement selection and outcomes by Kennedy, J

“…In patients sufficiently symptomatic to be offered replacement, about half of patients are eligible for partial replacement, with younger patients more likely to be eligible for medial replacement whilst older patients are more eligible for total replacement. …”

Protocol for project MIME: Motivation, Inflammation, and Mood in Emerging Adults by Daniel P. Moriarity, Marin M. Kautz, Kubarah Ghias, Kirsta Pennypacker, Eddie Harmon-Jones, Lauren B. Alloy

“…Project MIME (Motivation, Inflammation, and Mood in Emerging Adults) was designed to test this model in the context of a novel, reward-salient stressor (the Anger Incentive Delay Task, AIDT). …”
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Burden of predominant psychological reactions among the healthcare workers and general population during COVID-19 pandemic phase: A systematic review and meta-analysis by Bhaskar Thakur, Mona Pathak

“…Aim: Present systematic review and meta-analysis examined the burden of psychological reactions predominantly anxiety, depression, stress, and insomnia during the novel COVID-19 pandemic phase among the frontline healthcare, nonfrontline healthcare, and general population. …”
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Assessments Used for Summative Purposes during Internal Medicine Specialist Training: A Rapid Review by Scott Patterson, Louise Shaw, Michelle M Rank, Brett Vaughan

“…Ten eligible studies were included. Four studied the mini-clinical evaluation exercise (mini-CEX), two the Royal Australasian College of Physicians short case exam, three a variety of Entrustable Professional Activities (EPAs) or summative entrustment and progression review processes, and one a novel clinical observation tool. …”
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