Cross-sectional observational study of the availability of evidence supporting novel implantable devices used in gastrointestinal surgery. by Chapman, S, Shelton, B, Maruthappu, M, Singh, P, McCulloch, P, Bhangu, A

“… <h4>Background</h4> <p>Evidence supporting the implementation of novel surgical devices is unstandardized, despite recommendations for assessing novel innovations. …”

Exosomal microRNAs as novel diagnostic biomarkers in breast cancer: A systematic evaluation and meta-analysis by Fangcheng Hong, Ning Li, Zheming Feng, Yuxin Zheng, Chunyue Zhu, Fenghua Zhang

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A novel nomogram predicting early neurological deterioration after intravenous thrombolysis for acute ischemic stroke by Bang Luo, Mei Yuan, Wending Kuang, Yuzheng Wang, Liucui Chen, Yang Zhang, Gang Chen

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A Novel Systematic Oxidative Stress Score Predicts the Survival of Patients with Early-Stage Lung Adenocarcinoma by Jia-Yi Qian, Yun Hao, Hai-Hong Yu, Lei-Lei Wu, Zhi-Yuan Liu, Qiao Peng, Zhi-Xin Li, Kun Li, Yu’e Liu, Rang-Rang Wang, Dong Xie

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Exploring the Promise of Second-Line Chemotherapy in Biliary Tract Tumours: A Glimpse into Novel Treatment Approaches by Paula Villalba Cuesta, Mercedes Avedillo Ruidiaz, Eva Ruiz Hispán, Raquel Fuentes Mateos, Angela Lamarca

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A novel technology named as selective fenestration and axial decompression for the surgical management of lumbar degenerative diseases by Yang Hou, Tianyi Zhao, Xiaowen Liu, Jiangang Shi, Guodong Shi

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A Novel Inflammatory-Nutritional Prognostic Scoring System for Patients with Diffuse Large B Cell Lymphoma by Wang Z, Bao Y, Xu Z, Sun Y, Yan X, Sheng L, Ouyang G

“…Eligible patients were randomly divided into training and validation cohorts (n = 281 and 71, respectively) in an 8:2 ratio. …”
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Targeting the NAD Salvage Synthesis Pathway as a Novel Therapeutic Strategy for Osteosarcomas with Low NAPRT Expression by Natasja Franceschini, Jan Oosting, Maud Tamsma, Bertine Niessen, Inge Briaire-de Bruijn, Brendy van den Akker, Alwine B. Kruisselbrink, Ieva Palubeckaitė, Judith V. M. G. Bovée, Anne-Marie Cleton-Jansen

“…These results suggest that targeting NAMPT in osteosarcoma could be considered as a novel therapeutic strategy, where low NAPRT expression can serve as a biomarker for the selection of eligible patients.…”
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A Novel Prescription Digital Therapeutic Option for the Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease by Naim Alkhouri, Katherine Edwards, Mark Berman, Heather Finn, Rafael Escandon, Paul Lupinacci, Nicole Guthrie, Angie Coste, Jesus Topete, Mazen Noureddin

“…This feasibility study explored the use of a novel prescription digital therapeutic (PDT) in this patient population. …”
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Characterization of engraftment dynamics in myelofibrosis after allogeneic hematopoietic cell transplantation including novel conditioning schemes by Sarah Jungius, Sarah Jungius, Franziska C. Adam, Kerstin Grosheintz, Michael Medinger, Andreas Buser, Jakob R. Passweg, Jörg P. Halter, Sara C. Meyer, Sara C. Meyer, Sara C. Meyer, Sara C. Meyer

“…Allogeneic hematopoietic cell transplantation (HCT) represents a potentially curative therapy for a limited subset of patients with advanced MF, who are eligible, but engraftment in MF vs. AML is delayed which promotes complications. …”
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Improved Cardiac Performance with Dexamethasone Therapy in Premature Neonates: Novel Insights Using Serial Echocardiographic Assessments by Jejelola Ladele, Ayman Saker, Talal Altamimi, Andrea De La Hoz, Renjini Lalitha, Michael R. Miller, Soume Bhattacharya

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Vaccine Acceptance During a Novel Student-led Emergency Department COVID-19 Vaccination Program by Carly Eastin, Brendan Moore, Aaron Moulton, Luke Lefler, Fuad Haydar, Morgan Sweere, Gavin Jones, Crystal Sparks, Austin Porter III, M. Kathryn Allison, Travis Eastin

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A Novel MADM Framework under <i>q</i>-Rung Orthopair Fuzzy Bipolar Soft Sets by Ghous Ali, Hanan Alolaiyan, Dragan Pamučar, Muhammad Asif, Nimra Lateef

“…In this research study, a novel hybrid model under the name of <i>q</i>-rung orthopair fuzzy bipolar soft set (<i>q</i>-ROFBSS, henceforth), an efficient bipolar soft generalization of <i>q</i>-rung orthopair fuzzy set model, is introduced and illustrated by an example. …”
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Robust Rank Aggregation and Least Absolute Shrinkage and Selection Operator Analysis of Novel Gene Signatures in Dilated Cardiomyopathy by Xiao Ma, Changhua Mo, Liangzhao Huang, Peidong Cao, Louyi Shen, Chun Gui

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Novel Approach to Pharmaceutical 3D-Printing Omitting the Need for Filament—Investigation of Materials, Process, and Product Characteristics by Thomas Pflieger, Rakesh Venkatesh, Markus Dachtler, Karin Eggenreich, Stefan Laufer, Dominique Lunter

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Novel three-dimensional acellular dermal matrix for prepectoral breast reconstruction: First year in review with BRAXON®Fast by Giorgio Berna, Alessia De Grazia, Elisa Antoniazzi, Marco Romeo, Francesco Dell’Antonia, Stefano Lovero, Paolo Marchica, Christian Rizzetto, Paolo Burelli

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A human tissue-based assay identifies a novel carrion blowfly strain for maggot debridement therapy by Takuma Yoshida, Hiroka Aonuma, Saori Otsuka, Hidetoshi Ichimura, Erisha Saiki, Kosei Hashimoto, Manabu Ote, Sari Matsumoto, Kimiharu Iwadate, Takeshi Miyawaki, Hirotaka Kanuka

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Novel Theranostic Approaches Targeting CCR4-Receptor, Current Status and Translational Prospectives: A Systematic Review by Joana Gorica, Maria Silvia De Feo, Ferdinando Corica, Marko Magdi Abdou Sidrak, Miriam Conte, Luca Filippi, Orazio Schillaci, Giuseppe De Vincentis, Viviana Frantellizzi

“…Background: With the high mortality rate of malignant tumors, there is a need to find novel theranostic approaches to provide an early diagnosis and targeted therapy. …”
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A novel referral strategy to enhance the enrollment of patients with heart failure in cardiac rehabilitation: A feasibility study by Anne Mette Schmidt, Jannie Rhod Bloch‐Nielsen, Helene Nørgaard, Loui Hannibal, Sarah Holm Junge Jensen, Lars Hermann Tang, Nanna Rolving

“…The novel referral strategy was well‐accepted, and enrollment rate approached an acceptable level.…”
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Generation of Mouse Model of Hemophilia A by Introducing Novel Mutations, Using CRISPR/Nickase Gene Targeting System by Mehdi Shamsara, Abbas Jamshidizad, Aidin Rahim-Tayefeh, Maliheh Davari, Ali Rajabi Zangi, Fatemeh Masoumi, Alireza Zomorodipour

“…The CRISPR/nickase system was successfully applied to generate mouselines with the knockout fviii gene. The two novel FVIIIKO mice demonstrated all clinical symptoms of hemophilia A, whichcould be successfully inherited. …”
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