Effects of add-on Celecoxib treatment on patients with schizophrenia spectrum disorders and inflammatory cytokine profile trial (TargetFlame): study design and methodology of a mul... by Strube, W, Aksar, A, Bauer, I, Barbosa, S, Benros, M, Blankenstein, C, Campana, M, Davidovic, L, Glaichenhaus, N, Falkai, P, Görlitz, T, Hansbauer, M, Heilig, D, Khalfallah, O, Leboyer, M, Martinuzzi, E, Mayer, S, Moussiopoulou, J, Papazova, I, Perić, N, Wagner, E, Schneider-Axmann, T, Simon, J, Hasan, A

“…With TargetFlame, we intended to investigate a novel precision medicine approach towards anti-inflammatory antipsychotic treatment augmentation using drug repurposing.…”

The Ultrasound Renal Stress Test for the Assessment of Functional Renal Reserve in Kidney Transplantation: A Pilot Study in Living Donors by Federico Nalesso, Francesca K. Martino, Marco Bogo, Elisabetta Bettin, Marianna Alessi, Lucia F. Stefanelli, Cristina Silvestre, Lucrezia Furian, Lorenzo A. Calò

“…This study explores the use of the Intra-Parenchymal Renal Resistive Index Variation (IRRIV) test, a novel non-invasive method, to measure RFR in living donors. …”
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Safety and Efficacy of Ultrasound-Guided Perineural Hydrodissection as a Minimally Invasive Treatment in Carpal Tunnel Syndrome: A Systematic Review by Valerio Sveva, Giacomo Farì, Annatonia Fai, Alessio Savina, Mattia Giuseppe Viva, Francesco Agostini, Maurizio Ranieri, Marisa Megna, Massimiliano Mangone, Marco Paoloni, Andrea Bernetti

“…Ultrasound-guided perineural hydrodissection (HD) is a novel technique that has been found to be effective in providing mechanical release of perineural adhesions and decompression of the nerve, reducing inflammation and edema and restoring its physiological function. …”
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Thromboprophylaxis during pregnancy and the puerperium: a systematic review and economic evaluation to estimate the value of future research by Sarah Davis, Abdullah Pandor, Fiona C Sampson, Jean Hamilton, Catherine Nelson-Piercy, Beverley J Hunt, Jahnavi Daru, Steve Goodacre, Rosie Carser, Gill Rooney, Mark Clowes

“…For the unselected postpartum population, the RAMs compared were Royal College of Obstetricians and Gynaecologists (RCOG), Swedish Society of Obstetrics and Gynecology (SFOG), Caprini and the novel Sultan RAM. In the subgroup of obese postpartum women, the only RAM included was the novel Ellis-Kahana RAM. …”
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Postprandial effects of dietary protein source on metabolic responses, appetite, and arterial stiffness indices in overweight and obese men: the study protocol for a randomized cro... by Zahra Dehnavi, Ali Jafarzadeh Esfehani, Omolbanin Hajhoseini, Hanieh Barghchi, Aliyeh Ghannadzadeh Yazdi, Zahra Khorasanchi, Mahdi Shadnoush, Reza Rezvani, Habibollah Esmaily, Mohammad Safarian

“…Discussion The findings of this study will provide novel insight regarding the acute effects of different protein sources on energy metabolism, appetite, and arterial stiffness as a significant cardiovascular disease (CVD) risk factor. …”
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A systematic review of midwives’ training needs in perinatal mental health and related interventions by Marine Dubreucq, Marine Dubreucq, Corinne Dupont, Corinne Dupont, Mijke P. Lambregtse-Van den Berg, Wichor M. Bramer, Catherine Massoubre, Julien Dubreucq

“…We used the Mixed Methods Appraisal Tool for study quality.ResultsOf 4969 articles screened, 66 papers met eligibility criteria (47 on knowledge, skills or attitudes and 19 on training programs). …”
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Design and methodology of the SARCopenia trajectories and associations with adverse clinical outcomes in patients on HemoDialysis: the SARC-HD study by Marvery P. Duarte, Marina S. Pereira, Victor M. Baião, Fábio A. Vieira, Maryanne Zilli Canedo Silva, Rodrigo R. Krug, Antônio J. Inda-Filho, Aparecido P. Ferreira, Ricardo M. Lima, Carla Maria Avesani, Otávio T. Nóbrega, Maycon M. Reboredo, Heitor S. Ribeiro, on behalf of the SARC-HD Study Group

“…Hence, our ambition is that the data acquired from SARC-HD study will provide novel and valuable evidence to support an adequate screening and management of sarcopenia in patients on HD.…”
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Deep Learning-Based ECG Arrhythmia Classification: A Systematic Review by Qiao Xiao, Khuan Lee, Siti Aisah Mokhtar, Iskasymar Ismail, Ahmad Luqman bin Md Pauzi, Qiuxia Zhang, Poh Ying Lim

“…Specifically, 368 studies meeting the eligibility criteria are included. A total of 223 (61%) studies use MIT-BIH Arrhythmia Database to design DL models. …”
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A Scoping Review on Accentuating the Pragmatism in the Implication of Mobile Health (mHealth) Technology for Tuberculosis Management in India by Jyotsna Needamangalam Balaji, Sreenidhi Prakash, Youngmok Park, Joon Sang Baek, Jaeyong Shin, Vasuki Rajaguru, Krishna Mohan Surapaneni

“…Even though the implementation of this novel strategy is escalating around the globe, its triumph is still sub optimal in India. …”
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Effects of six teaching strategies on medical students: protocol for a systematic review and network meta-analysis by Hong Gong, Lian Wang, Shuailong Zhang, Dongmei Zhu, Xiaqing Wang, Tianyao Liu, Xiaotang Fan

“…Introduction Mounting evidence has suggested that novel teaching strategies have a positive impact on the quality and efficiency of medical education. …”
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Efficacy of Digital Outreach Strategies for Collecting Smoking Data: Pragmatic Randomized Trial by Lauren E Kearney, Emily Jansen, Hasmeena Kathuria, Katrina Steiling, Kayla C Jones, Allan Walkey, Nicholas Cordella

“…Patient-generated health data is a novel approach to documenting smoking history; however, the comparative effectiveness of different approaches is unclear. …”
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A systematic review of genetic ancestry as a risk factor for incidence of non-small cell lung cancer in the US by Breanna A. James, Jennie L. Williams, Barbara Nemesure

“…At the genomic level, several novel predisposing variants associated with African ancestry and increased risk of NSCLC were discovered. …”
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Effect of tobacco and nicotine in causing staining of dental hard tissues and dental materials: A systematic review and meta‐analysis by Rijula R. Karanjkar, Philip M. Preshaw, Janice S. Ellis, Richard Holliday

“…This is of increasing relevance with the popularity of novel products such as heated‐tobacco products and electronic cigarettes (E‐cigarettes). …”
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Environmental Disinfection Strategies to Prevent Indirect Transmission of SARS-CoV2 in Healthcare Settings by Dorina Lauritano, Giulia Moreo, Luisa Limongelli, Michele Nardone, Francesco Carinci

“…(1) Introduction: The novel respiratory syndrome coronavirus 2 (SARS-CoV-2), also called coronavirus disease 2019 (COVID-19), is rapidly spreading in many countries and represents a public health emergency of international concern. …”
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Mendelian randomization studies on coronary artery disease: a systematic review and meta-analysis by Sarah Silva, Segun Fatumo, Dorothea Nitsch

“…Differences in the observed strengths of the respective relationships however are indicative of the value of increasing representation in non-European populations, as novel genetic pathways or functional SNPs relating to CAD may be uncovered through a more global analysis. …”
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Fecal Microbiota Transplantation in Decompensated Cirrhosis: A Systematic Review on Safety and Efficacy by Annie S. Hong, Kyaw Min Tun, Jenny M. Hong, Kavita Batra, Gordon Ohning

“…Studies on efficacy in novel treatment of hepatic encephalopathy have been promising. …”
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Safety and feasibility of transcutaneous vagus nerve stimulation in mild cognitive impairment: VINCI-AD study protocol by Helena Dolphin, Adam H. Dyer, Tim Dukelow, Ciaran Finucane, Sean Commins, Sean P Kennelly

“…Around 5–15% of individuals with MCI convert to dementia annually. Novel treatments which delay progression of MCI to dementia are urgently needed. …”
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The Practice and Willingness of Women Towards Opportunistic Screening for Breast and Cervical Cancers in Sichuan Province, China: A Cross-Sectional Study by Li H, Huang M, Yang Y, Tang J, Ye Y

“…Ethnic minorities, lower education levels, and menopause were inversely associated, whereas awareness of the screening methods and eligibility for screening were positively associated with physician-recommended and voluntary screenings (P < 0.05). …”
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Comparative Evaluation of Vestibular Incision Subperiosteal Tunnel Access (VISTA) Technique with other Tunneling Techniques: Protocol for a Systematic Review and Meta-analysis by Shrishti Satish Salian, Prasad V Dhadse, Pavan Bajaj, Ranu R Oza

“…The increasing demand for aesthetics by patients has led dentists to adopt newer and more novel techniques. Since Allen first introduced the tunneling technique in 1994, several procedural adjustments have been suggested. …”
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Impact of sampling and data collection methods on maternity survey response: a randomised controlled trial of paper and push-to-web surveys and a concurrent social media survey by Harrison, S, Alderdice, F, Quigley, MA

“…<p><strong>Background</strong> Novel survey methods are needed to tackle declining response rates. …”