Mitochondrial ROS and the effectors of the intrinsic apoptotic pathway in aging cells: the discerning killers! by Siegfried Hekimi, Ying Wang, Alycia Noe

“…These cells cannot simply be killed and replaced when showing signs of dysfunction. …”
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PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity by Anita Schmitt, Brigitte Neuber, Michael Schmitt, Melanie Märklin, Boris Klimovich, Claudia Lengerke, Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Daniela Chmiest, Silvia Podavini, Fulya Korkmaz, Corina Schneidawind, Dominik Schneidawind

“…Chimeric antigen receptors (CAR) redirect effector cells to cell surface antigens and enhance killing of target cells. With this study, we aimed to combine enhanced cytotoxicity of CD19-CAR-iNKT cells against lymphoma cells with their tolerogenic properties.Methods iNKT cells were isolated from peripheral blood mononuclear cells and transduced with an anti-CD19-CAR retrovirus. …”
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Salmonella Typhimurium Triggers Extracellular Traps Release in Murine Macrophages by Amy Mónaco, Nicole Canales-Huerta, Nicole Canales-Huerta, Jorge Jara-Wilde, Jorge Jara-Wilde, Steffen Härtel, Steffen Härtel, Steffen Härtel, Steffen Härtel, Jose Alejandro Chabalgoity, María Moreno, Paola Scavone

“…Neutrophils are known for killing bacteria through oxidative burst, amid other mechanisms. …”
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Le Tanger expérimental de William Burroughs by Xavier Garnier

“…Tangier is not only for Burroughs a town where homosexual prostitution and drugs traffic are easy, it is a place where a contact was established with obscure forces that the man who accidentally killed his own wife few years earlier, was seeking to encounter.…”
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The contribution of forensic odontology in the Highland Towers Condominium disaster by Alhabshi, S.F., Nambiar, P.

“…Difficulties were also encountered during the procurement and deciphering of information from dental records. …”

An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations by Marcos H de Moraes, FoSheng Hsu, Dean Huang, Dustin E Bosch, Jun Zeng, Matthew C Radey, Noah Simon, Hannah E Ledvina, Jacob P Frick, Paul A Wiggins, S Brook Peterson, Joseph D Mougous

“…The potential for such encounters to have long-term beneficial consequences in recipient cells has not been investigated. …”
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Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell. by Mcmichael, A, Askonas, B

“…The use of virus-infected normal lymphoid cells as target cells overcame the difficulties of nonspecific killing encountered with some transformed cells.…”

TREATMENT OF FALCIPARUM-MALARIA by Looareesuwan, S, Warrell, D

“…The treatment of falciparum malaria, one of the world's major killing diseases, has been complicated by development of resistance to a number of antimalarial drugs, principally chloroquine. …”

A Study of a Sample of Facebook Users Finds They Do Not Seek Political News through Facebook But Are Exposed to Political News through This Medium by Elizabeth Margaret Stovold

“…However, they estimated around 24% of the posts they see were concerned with political news, and when encountered, these stories are frequently read (M 3.53, SD=1.18). …”
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Interaction of Streptococcus pyogenes with extracellular matrix components resulting in immunomodulation and bacterial eradication by Lucie Colineau, Maisem Laabei, Guanghui Liu, David Ermert, John D. Lambris, Kristian Riesbeck, Anna M. Blom

“…In severe invasive infections, S. pyogenes encounters and interacts with components of the extracellular matrix (ECM), including small leucine rich-proteoglycans (SLRPs). …”
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Exploring the distinct immunological reactions of bovine neutrophils towards major and minor pathogens responsible for mastitis by Anyaphat Srithanasuwan, Laorat Tata, Warunya Tananupak, Weerin Jaraja, Witaya Suriyasathaporn, Phongsakorn Chuammitri

“…The results reveal that neutrophils performed offensive duties regardless of the type of bacteria encountered. Neutrophils generated high levels of reactive oxygen species, efficiently phagocytosed both types of bacteria, and facilitated extracellular killing by releasing NET structures against all bacteria. …”
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The Transcription Factor Sfp1 Regulates the Oxidative Stress Response in <i>Candida albicans</i> by Shao-Yu Lee, Hsueh-Fen Chen, Ying-Chieh Yeh, Yao-Peng Xue, Chung-Yu Lan

“…<i>albicans</i> frequently encounters immune cells and antifungal drugs, many of which exert their antimicrobial activity by inducing the production of reactive oxygen species (ROS). …”
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<named-content content-type="genus-species">Staphylococcus aureus</named-content> Uses the GraXRS Regulatory System To Sense and Adapt to the Acidified Phagolysosome in Macrophages by Ronald S. Flannagan, Robert C. Kuiack, Martin J. McGavin, David E. Heinrichs

“…We conclude that GraXRS represents a vital regulatory system that functions to allow S. aureus to evade killing, prior to commencement of replication, within host antibacterial immune cells. …”
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Agentes antineoplásicos biorredutíveis: uma nova alternativa para o tratamento de tumores sólidos by Oliveira Renata Barbosa de, Alves Ricardo José

“…A problem often encountered in cancer therapy is the presence of tumor cell subpopulation that are resistant to treatment. …”
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Chronic granulomatous disease: a review of the infectious and inflammatory complications by Sahni Ryan, Jithpratuck Warit, Saleh Hana, Jaishankar Gayatri, Song EunKyung, Krishnaswamy Guha

“…<p>Abstract</p> <p>Chronic Granulomatous Disease is the most commonly encountered immunodeficiency involving the phagocyte, and is characterized by repeated infections with bacterial and fungal pathogens, as well as the formation of granulomas in tissue. …”
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Reflect Of Epic in Elhami Kermanshahi's Shahed-Nameh by هوشنگ محمدی افشار, سیّد امیر جهادی حسینی, محمدرضا یعقوبی چترودی

“…In what follows, some of the similarities of Shahednameh and Shahnameh are mentioned: The use of weapons and ammunition: In Shahednameh, like Shahname, we encounter so many cases of referring to weapons used at war. …”
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Immune System and Diseases / by Goodman, Vinita, author 648342, Horner, Jeromy, author 648343

“…An immune system is a system of biological structures and processes within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own healthy cells and tissues in order to function properly. …”
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Visualizing the dynamics of HIV-specific cytotoxic T-cells in extracellular matrix by Foley, Maria Hottelet

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ATG Ubiquitination Is Required for Circumsporozoite Protein to Subvert Host Innate Immunity Against Rodent Malaria Liver Stage by Hong Zheng, Hong Zheng, Hong Zheng, Xiao Lu, Xiao Lu, Kai Li, Feng Zhu, Chenhao Zhao, Taiping Liu, Yan Ding, Yong Fu, Kun Zhang, Taoli Zhou, Jigang Dai, Yuzhang Wu, Wenyue Xu, Wenyue Xu

“…Here, we showed that sporozoite circumsporozoite protein (CSP) translocated from the parasitophorous vacuole into the hepatocyte cytoplasm significantly mediated the resistance to the killing of EEFs by interferon-gamma (IFN-γ). Attenuation of IFN-γ-mediated killing of EEFs by CSP was dependent on its ability to reduce the levels of autophagy-related genes (ATGs) in hepatocytes. …”
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The dental identification of victims of an aircraft accident in Malaysia by Nambiar, P., Jalil, N., Singh, B.

“…Difficulties were also encountered during the procurement and deciphering of information from dental records. …”
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