Behavioral problems in children with epilepsy in rural Kenya. by Kariuki, S, Abubakar, A, Holding, P, Mung'ala-Odera, V, Chengo, E, Kihara, M, Neville, BG, Newton, C

“…The aims of this study were to record behavioral problems in children with epilepsy (CWE), compare the prevalence with that reported among healthy children without epilepsy, and investigate the risk factors. …”

Behavioral problems in children with epilepsy in rural Kenya by Kariuki, S, Abubakar, A, Holding, P, Mung'ala-Odera, V, Chengo, E, Kihara, M, Neville, BG, Newton, C

“…The aims of this study were to record behavioral problems in children with epilepsy (CWE), compare the prevalence with that reported among healthy children without epilepsy, and investigate the risk factors. …”

Glycine receptor antibodies in a boy with focal epilepsy and episodic behavioral disorder by Wuerfel, E, Bien, C, Vincent, A, Woodhall, M, Brockmann, K

Glycine receptor antibodies in a boy with focal epilepsy and episodic behavioral disorder. by Wuerfel, E, Bien, C, Vincent, A, Woodhall, M, Brockmann, K

p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice by Vernì, Fiammetta, Saggio, Isabella, Burla, Romina, La Torre, Mattia, Zanetti, Giorgia, Bastianelli, Alex, Merigliano, Chiara, Del Giudice, Simona, Vercelli, Alessandro, Di Cunto, Ferdinando, Boido, Marina

“…Epilepsy is a complex clinical condition characterized by repeated spontaneous seizures. …”
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Quality of life in Malaysian children with epilepsy by Fong, Choong Yi, Chang, Wei Mun, Kong, Ann Nie, Rithauddin, Ahmad Mohamed, Khoo, Teik Beng, Ong, Lai Choo

PENGARUH ASAM VALPROAT TERHADAP PRESTASI BELAJAR ANAK DENGAN EPILEPSI by , Andrianto Selohandono, , Prof. dr. Harsono, Sp.S.(K)

“…Valproic acid is one of the AED commonly prescribed to control epileptic seizure. Cognitive and behavioral disorder have been associated with barbiturate and benzodiazepine, while their association with valproic acid is still a matter of debate. …”

Positive psychological interventions for people with epilepsy: An assessment on factors related to intervention participation by Lai, Siew Tim, Lim, Kheng Seang, Tang, Venus, Low, Wah Yun

Exploring the needs and challenges of parents and their children in childhood epilepsy care: A qualitative study by Wo, Su Woan, Ong, Lai Choo, Low, Wah Yun, Lai, Pauline Siew Mei

“…However, parents and children had different views on how epilepsy impacted on the child emotionally, as well as behavioral and interpersonal relationship with peers.…”

A homozygous variant disrupting the PIGH start‐codon is associated with developmental delay, epilepsy, and microcephaly by Pagnamenta, A, Murakami, Y, Anzilotti, C, Titheradge, H, Oates, A, Morton, J, DDD Study, Kinoshita, T, Kini, U, Taylor, J

“…For eight genes critical to this biological process, disease associations are not yet reported. Scanning exomes from 7,833 parent–child trios and 1,792 singletons from the DDD study for biallelic variants in this gene‐set uncovered a rare PIGH variant in a boy with epilepsy, microcephaly, and behavioral difficulties. …”

A companion to the preclinical common data elements and case report forms for rodent EEG studies: A report of the TASK3 EEG Working Group of the ILAE/AES Joint Translational Task F... by Ono, T, Wagenaar, J, Giorgi, F, Fabera, P, Hanaya, R, Jefferys, J, Moyer, J, Harte-Hargrove, L, Galanopoulo, A

“…In contrast, preclinical EEG studies demonstrate more variability and diversity than clinical studies in the types and locations of EEG electrodes, methods of data analysis, and scoring of EEG patterns and associated behaviors. The TASK3 EEG working group of the International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force has developed a set of preclinical common data elements (CDEs) and case report forms (CRFs) for recording, analysis and scoring of animal EEG studies. …”

Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice by Taylor, M., Gisin, E., Sidorov, Michael, Krueger, Dilja, Osterweil, Emily, Bear, Mark

“…Previous studies have shown that partial inhibition of metabotropic glutamate receptor signaling is sufficient to correct behavioral phenotypes in a mouse model of FX, including audiogenic seizures, open-field hyperactivity and social behavior. …”
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Prevalence, causes, and behavioral and emotional comorbidities of acute symptomatic seizures in Africa: A critical review by Kariuki, S, Abubakar, A, Stein, A, Marsh, K, Newton, C

“…The underlying neurological damage in acute symptomatic seizures can lead not only to behavioral and emotional problems but also to neurocognitive impairment and epilepsy. …”

Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice. by Hayashi, S, Inoue, Y, Hattori, S, Kaneko, M, Shioi, G, Miyakawa, T, Takeichi, M

“…Here, we report the effects of <em>Pcdh19</em> knockout in mice on their development and behavior. …”

Malaria by Newton, CRJC

“…The epilepsy following malaria is often associated with considerable comorbidity, particularly behavioral and neurocognitive impairment in children. …”

Childhood autism spectrum disorder: Insights from a tertiary hospital cohort in Kenya by Samia, P, Kanana, M, King, J, Donald, KA, Newton, CR, Denckla, C

“…Preliminary studies reported a high male sex ratio, excess of non-verbal cases, possible infectious etiologies and comorbidities e.g. epilepsy.…”

Multi-center clinical assessment of improved wearable multimodal convulsive seizure detectors by Onorati, Francesco, Regalia, Giulia, Caborni, Chiara, Migliorini, Matteo, Bender, Daniel, Frazier, Cherise, Kovitch Thropp, Eliana, Mynatt, Elizabeth D., Bidwell, Jonathan, Mai, Roberto, LaFrance, W. Curt Jr, Blum, Andrew S., Friedman, Daniel, Loddenkemper, Tobias, Mohammadpour-Touserkani, Fatemeh, Reinsberger, Claus, Tognetti, Simone, Ming Zher, Poh, Picard, Rosalind W.

“…Objective New devices are needed for monitoring seizures, especially those associated with sudden unexpected death in epilepsy (SUDEP). They must be unobtrusive and automated, and provide false alarm rates (FARs) bearable in everyday life. …”
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Integrated human-machine interface for closed-loop stimulation using implanted and wearable devices by Sladky, V, Kremen, V, McQuown, K, Mivalt, F, Brinkmann, BH, Gompel, JV, Miller, KJ, Denison, T, Worrell, GA

“…The system enables precise time synchronization of the external components with the brain stimulating device and is coupled with automated analysis of continuous streaming electrophysiology synchronized with patient reports. The system leverages a real-time bi-directional interface between devices and patients with epilepsy living in their natural environment.…”

Disease related variables and psychological problems among chFonically ill children in Malaysia by Azizah, Othman

“…Methods: Parents' ratings of children behavioral and emotional problems (i.e. Child Behavior Checklist - CBCL), disease-related and socio-demographic information were obtained from 63 parents of children suffering from cancer. epilepsy, and asthma seen in Institute of Pediatrics, Kuala Lumpur General Hospital. …”
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Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome by Menke, LA, Gardeitchik, T, Hammond, P, Heimdal, KR, Houge, G, Hufnagel, SB, Ji, J, Johansson, S, Kant, SG, Kinning, E, Leon, EL, Newbury-Ecob, R, Paolacci, S, Pfundt, R, Ragge, NK, Rinne, T, Ruivenkamp, C, Saitta, SC, Sun, Y, Tartaglia, M, Terhal, PA, van Essen, AJ, Vigeland, MD, Xiao, B, Hennekam, RC

“…The main characteristics of the patients are developmental delay (90%), autistic behavior (65%), short stature (42%), and microcephaly (43%). …”