Searching potential antiviral candidates for the treatment of the 2019 novel coronavirus based on DFT calculations and molecular docking by Abir Sagaama, Silvia Antonia Brandan, Takoua Ben Issa, Noureddine Issaoui

“…In the present work, the succinic acid (SA), L-pyroglutamic acid (L-PGA), N-phenyl-thioacetamide (N-NPTA), 2-amino-5-chloropyridine hydrogen succinate (ACPS), epigallocatechine Gallate (EGCG) or KDH and, selenomethionine (SeM) compounds have been proposed as potential antiviral candidates to treatment of COVID-19 based on B3LYP/6-311++G∗∗ calculations and molecular docking. …”
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Therapeutic potential of polyphenols against aging- induced idiopathic pulmonary fibrosis (IPF) via Bioinformatics analysis by Ankit Tripathi, Deepika Tripathi, Manish Shukla, Meenakshi Sharma

“…Results: The present study aimed at investigating the possible dietary flavonoid therapy (Quercetin, baicalin, luteolin, curcumin, rutin, and epigallocatechin gallate (EGCG)) attenuating the activation of mTORC1 in the lung epithelia by molecular docking approaches to ascertain the binding affinities of phytoflavonoids towards AhR and FK506 binding protein (FKBP12) over the known IPF synthetic inhibitors - pirfenidone and nintedanib. …”
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A novel extraction method enhanced the osteogenic and anti-osteoporosis effect of tea extract without any hepatotoxicity in ovariectomized rats by Chirag Kulkarni, Chirag Kulkarni, Shivani Sharma, Shivani Sharma, Prateek Singh Bora, Prateek Singh Bora, Saurabh Verma, Saurabh Verma, Swati Rajput, Swati Rajput, Konica Porwal, Srikanta Kumar Rath, Srikanta Kumar Rath, Jiaur Rahaman Gayen, Jiaur Rahaman Gayen, Upendra Sharma, Naibedya Chattopadhyay, Naibedya Chattopadhyay

“…Tea (Camellia sinensis) has several reported health benefits, including that on bone health attributed to catechins of which the most abundant is epigallocatechin-3-gallate (EGCG). However, several preclinical and clinical studies raise safety concerns about EGCG in tea extract causing acute liver failure. …”
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The roles of theaflavins in reducing dentin erosion by Jing Guo, Mingqi Yang, Mengna Hu

“…For the effect of TFs on dentin erosion, 6 experimental groups (n = 5) were treated with 1% epigallocatechin gallate [EGCG], 1% chlorhexidine [CHX], 1%, 2%, 4%, and 8% TFs for the 30 s and then subjected to erosion cycles (4 cycles/d for 7 d). …”
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Exploration and Comparison of the Behavior of Some Indigenous and International Varieties (<i>Vitis vinifera</i> L.) Grown in Climatic Conditions of Herzegovina: The Influence of V... by Tatjana Jovanović-Cvetković, Milica Sredojević, Maja Natić, Rada Grbić, Milica Fotirić Akšić, Sezai Ercisli, Miljan Cvetković

“…The most abundant polyphenols in the analyzed grape samples were quercetin 3-<i>O</i>-glucoside and catechin gallate, followed by kaempferol 3-<i>O</i>-glucoside. …”
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The therapeutic role and potential mechanism of EGCG in obesity-related precocious puberty as determined by integrated metabolomics and network pharmacology by Qiuyun Gu, Lina Xia, Qiuju Du, Ying Shao, Jieyi He, Peiying Wu, Lingwei Liang, Xiuhua Shen, Xiuhua Shen

“…Objective(-)-Epigallocatechin-3-gallate (EGCG) has preventive effects on obesity-related precocious puberty, but its underlying mechanism remains unclear. …”
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Stenotrophomonas maltophilia as an Emerging Ubiquitous Pathogen: Looking Beyond Contemporary Antibiotic Therapy by Anthony A. Adegoke, Anthony A. Adegoke, Anthony A. Adegoke, Thor A. Stenström, Anthony I. Okoh, Anthony I. Okoh

“…Incorporating several other proven approaches like bioengineered bacteriophage therapy, Epigallocatechin-3-gallate (EGCG), essential oil, nanoemulsions, and use of cationic compounds are promising alternatives which can be incorporated in Stenotrophomonas control arsenal.…”
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Beyond Antioxidant Activity: Redox Properties of Catechins May Affect Changes in the DNA Methylation Profile—The Example of <i>SRXN1</i> Gene by Patrycja Jakubek, Jovana Rajić, Monika Kuczyńska, Klaudia Suliborska, Mateusz Heldt, Karol Dziedziul, Melita Vidaković, Jacek Namieśnik, Agnieszka Bartoszek

“…Based on these findings, we present a proof-of-concept that DNA methylation, which limits <i>SRXN1</i> expression and thus restricts the multidirectional antioxidant action of SRXN1, may represent a mechanism protecting cells against reductive stress caused by particularly fast-reacting reductants such as EGC and (−)-epicatechin gallate (ECG) in our study.…”
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Transport of Dietary Anti-Inflammatory Peptide, γ-Glutamyl Valine (γ-EV), across the Intestinal Caco-2 Monolayer by Snigdha Guha, Sophie Alvarez, Kaustav Majumder

“…Cytochalasin-D disintegrated the tight-junction proteins of the Caco-2 monolayer and increased the P_app of γ-EV to 4.36 × 10⁻⁶ ± 0.16 × 10⁻⁶ cm/s (<i>p</i> < 0.001), while theaflavin 3′-gallate and Gly-Sar significantly decreased the P_app (<i>p</i> < 0.05), with wortmannin having no effects on the peptide transport, indicating that the transport route of γ-EV could be via both PepT1-mediated and paracellular.…”
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Valorisation of Grape Stems as a Source of Phenolic Antioxidants by Using a Sustainable Extraction Methodology by Juan Antonio Nieto, Susana Santoyo, Marin Prodanov, Guillermo Reglero, Laura Jaime

“…Forty-two phenolic compounds were identified in the optimal extract, mainly polymer procyanidins and, to a lesser extent, monomers and oligomers of flavan-3-ols, quercetin-3-<i>O</i>-glucuronide, ε-viniferin, gallic and caftaric acid. Ethyl gallate, ellagic acid, protocatechuic aldehyde, delphinidin-7-<i>O</i>-glucoside and cyanidin-3-<i>O</i>-glucoside were reported for the first time in grape stem extracts. …”
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Resveratrol, EGCG and Vitamins Modulate Activated T Lymphocytes by Joseph Schwager, Nicole Seifert, Albine Bompard, Daniel Raederstorff, Igor Bendik

“…We investigated the effects of vitamins (vitamin A (VA), D (VD), E (VE)) and bioactives (i.e., resveratrol (Res), epigallocatechin-3-gallate (EGCG)) on the adaptive immune response, as well as their synergistic or antagonistic interactions. …”
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Comparison of phenolic composition in date (Phoenix dactylifera L.) flesh and seeds extracted by an ultrasonic-assisted and conventional method by Linghong Shi, Wu Li, Mohammad Shafiur Rahman, Nasser Al-Habsi, Muthupandian Ashokkumar, Frank R. Dunshea, Hafiz A.R. Suleria

“…The extract also contained epicatechin (36.12 μg/g), coumaric acid (27.05 μg/g), p-hydroxybenzoic acid (21.03 μg/g), syringic acid (19.85 μg/g), and epicatechin gallate (11.67 μg/g). The results showed that ultrasonic-assisted extraction could significantly increase the quantities of functional components of the extracts obtained from fresh date fruit samples.…”
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Phytochemical Profiles, Antioxidant Activity and Antiproliferative Mechanism of <i>Rhodiola rosea</i> L. Phenolic Extract by Sheng Zhang, Siqi Jiang, Na Deng, Bisheng Zheng, Tong Li, Rui Hai Liu

“…High-performance liquid chromatography (HPLC) results demonstrated that the main phenolics of were epigallocatechin (EGC), epigallocatechin gallate (EGCG), gallic acid (GA) and catechin. Gas chromatography–mass spectrometry (GC-MS) analysis found that <i>Rhodiola rosea</i> L. was rich in volatile phytochemicals. …”
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Curso online masivo abierto para mejorar la práctica preprofesional en la Universidad Nacional de Educación by David Olivier Denis Choin, Edison Javier Padilla Padilla

“…Para ello, se han tomado como principales referencias teóricas los aportes de Aguerrondo (1992); Fullan (1998); y Blanco y Messina (2000). Este trabajo sistematiza los elementos innovadores que se congregaron en el Curso Online Masivo y Abierto (MOOC) en la Aproximación al modelo de Práctica Preprofesional. …”
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Naringin from Coffee Inhibits Foodborne <i>Aspergillus fumigatus</i> via the NDK Pathway: Evidence from an In Silico Study by Shashanka K. Prasad, Smitha S. Bhat, Olga Koskowska, Jiraporn Sangta, Sheikh F. Ahmad, Ahmed Nadeem, Sarana Rose Sommano

“…As determined by the molecular docking interactions of the library compounds indicated, the best interactions were found to occur between the nucleoside-diphosphate kinase protein 6XP7 and the test molecules Naringin (−6.771 kcal/mol), followed by Epigallocatechin gallate (−5.687 kcal/mol). Therefore, Naringin was opted for further validation with molecular dynamic simulations. …”
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Dynamic changes in chemical composition and microbial community characteristics during pile-fermentation process of Phyllanthus emblica Linn. fruit by Haozhou Huang, Mengqi Li, Gefei Li, Yurou Jiang, Jingping Zhong, Jun Liu, Xiaoming Bao, Sanhu Fan, Taigang Mo, Dingkun Zhang, Li Han, Junzhi Lin

“…Among these, 5 compounds, such as 2-O-galloyl-1,4-galactolactone and 1-methyl-2-gallate galactose ester, showed a downward trend, whereas 13 compounds, including corilagin and chebulitic acid, exhibited an upward trend. …”
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Divya-WeightGo combined with moderate aerobic exercise remediates adiposopathy, insulin resistance, serum biomarkers, and hepatic lipid accumulation in high-fat diet-induced obese... by Acharya Balkrishna, Sonam Sharma, Madhulina Maity, Meenu Tomer, Rani Singh, Vivek Gohel, Rishabh Dev, Sandeep Sinha, Anurag Varshney

“…Ultra-high performance liquid chromatography (UHPLC) analysis revealed the presence of phytocompounds including gallic acid, methyl gallate, corilagin, ellagic acid, pentagalloyl glucose, withaferin A and hydroxycitric acid, proven to aid in weight loss. …”
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Metabolomic NMR analysis and organoleptic perceptions of pomegranate wines: Influence of cultivar and yeast on the product characteristics by Chiara Roberta Girelli, Paride Papadia, Francesca Pagano, Pier Paolo Miglietta, Massimiliano Cardinale, Laura Rustioni

“…In particular, a higher content of citrate and gallate was observed for the Smith cv. and, on the contrary, a statistically significant higher content of fructose, malate, glycerol, 2,3 butanediol, trigonelline, aromatic amino acids and 4-hydrophenylacetate was observed in Jolly Red pomegranate wines samples. …”
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Chemical and Pharmacological Potential of <i>Coccoloba cowellii</i>, an Endemic Endangered Plant from Cuba by Daniel Méndez, Julio C. Escalona-Arranz, Kenn Foubert, An Matheeussen, Anastasia Van der Auwera, Stefano Piazza, Ann Cuypers, Paul Cos, Luc Pieters

“…The major constituents were glucuronides and glycosides of myricetin and quercetin, as well as epichatechin-3-<i>O</i>-gallate, catechin, epicatechin and gallic acid, all of them being reported for the first time in <i>C. cowellii</i> leaves. …”
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Comprehensive and Rapid Quality Evaluation Method for the Ayurvedic Medicine Divya-Swasari-Vati Using Two Analytical Techniques: UPLC/QToF MS and HPLC–DAD by Acharya Balkrishna, Sudeep Verma, Priyanka Sharma, Meenu Tomer, Jyotish Srivastava, Anurag Varshney

“…Eleven marker components, namely gallic acid, protocatechuic acid, methyl gallate, ellagic acid, coumarin, cinnamic acid, glycyrrhizin, eugenol, 6-gingerol, piperine and glabridin, were selected out of seventy-four identified makers for the quantitative analysis in DSV formulation. …”
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