Plecanatide Improves Symptoms of Irritable Bowel Syndrome with Constipation: Results of an Integrated Efficacy and Safety Analysis of Two Phase 3 Trials by Brenner DM, Dorn SD, Fogel RP, Christie J, Laitman AP, Rosenberg J

“…Darren M Brenner,1 Spencer D Dorn,2 Ronald P Fogel,3 Jennifer Christie,4 Adam P Laitman,5 Jonathan Rosenberg6 1Internal Medicine-Gastroenterology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA; 2Division of Gastroenterology and Hepatology, UNC School of Medicine, Chapel Hill, NC, USA; 3Digestive Health Center of Michigan, Chesterfield, MI, USA; 4Emory University School of Medicine, Atlanta, GA, USA; 5Salix Pharmaceuticals, Bridgewater, NJ, USA; 6GI Alliance of Illinois, Gurnee, IL, USACorrespondence: Darren M Brenner, MD, FACG, AGAF, RFF, Northwestern Memorial Hospital/Arkes Family Pavilion, 676 N St Clair Street, Suite 1400, Chicago, IL, 60611, USA, Tel +1 312 695 8132, Fax +1 312 695 3999, Email Darren.Brenner@nm.orgPurpose: Patients with irritable bowel syndrome with constipation (IBS-C) experience abdominal pain with altered bowel movements. …”
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