The function of NOD2 in antigen presenting cells by Allan, P

“…<p>Crohn’s disease (CD), a chronic inflammatory condition of the gut affecting 1:1000 of western populations, is thought to arise from a dysregulated immune response in a genetically susceptible individual. …”

Accurate identification and quantification of commensal microbiota bound by host immunoglobulins by Jackson, MA, Pearson, C, Ilott, NE, Huus, KE, Hegazy, AN, Webber, J, Finlay, BB, Macpherson, AJ, Powrie, F, Lam, LH

“…Combined with a novel scoring method for IgA-Seq datasets that accounts for the aforementioned effects, this platform enables accurate identification and quantification of commensal gut microbiota targeted by host immunoglobulins.…”

Microbial Reprogramming Inhibits Western Diet-Associated Obesity by Poutahidis, Theofilos, Kleinewietfeld, Markus, Levkovich, Tatiana, Bhela, Siddheshvar, Chatzigiagkos, Antonis, Hafler, David A., Alm, Eric J., Erdman, Susan E., Varian, Bernard, Ibrahim, Yassin, Lakritz, Jessica, Kearney, Sean Michael, Smillie, Chris Scott, Perrotta, Allison Rose

“…Specifically, bacterial effects depended upon active immune tolerance by induction of Foxp3[superscript +] regulatory T cells (Treg) and interleukin (Il)-10, without significantly changing the gut microbial ecology or reducing ad libitum caloric intake. …”
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