-
21
Gut Microbiota and the Paradox of Cancer Immunotherapy
Published 2014“…Stimulated by a gut microbiota-centric systemic homeostasis hypothesis, we set out to explore the influence of the gut microbiome to explain the paradoxical roles of regulatory T-lymphocytes in cancer development and growth. …”
Get full text
Article -
22
Regional diets targeting gut microbial dynamics to support prolonged healthspan
Published 2021“…As ageing is an inevitable, non-reversing and highly individualised process, we need to better understand how non-genetic factors like diet choices and commensal gut microbes can modulate the biology of ageing. …”
Get full text
Journal Article -
23
Transmission ecology of the gut microbiota in wild mice
Published 2021“…Further, these two transmission routes seem to transmit different sets of gut microbes, with environmental transmission being influential for aerotolerant bacteria while social networks functioning as a transmission pathway specifically for anaerobic microbes. …”
Thesis -
24
Structural and functional investigation revealed gut microbiota-derived peptidoglycan disaccharides as immunomodulatory molecules that maintain host gut homeostasis
Published 2024“…In this thesis, I developed a HPLC-HRMS/MS-based workflow to reveal the total PGN loads and to identify the main players of PGN reservoirs in the host gut and blood. Exploiting the current protocol, I unraveled PGN levels in healthy hosts and their dynamic changes in the gut upon antibiotics perturbation. …”
Get full text
Thesis-Doctor of Philosophy -
25
Ecological principles of colonisation resistance in the gut microbiome
Published 2023“…<p>The mammalian gut is home to hundreds of species of microbes, collectively known as the gut microbiome. …”
Thesis -
26
Two dynamic regimes in the human gut microbiome
Published 2017“…The gut microbiome is a dynamic system that changes with host development, health, behavior, diet, and microbe-microbe interactions. …”
Get full text
Get full text
Get full text
Get full text
Article -
27
Isolation and identification of microbes to convert green wastes to sugars for ethanol production
Published 2009“…In this study, bacterial communities which played the key physiological function in cellulose and hemicellulose digestion within the guts of the larvae of the yellow mealworm, Tenebrio molitor L. were investigated. …”
Get full text
Final Year Project (FYP) -
28
Exploring the role of gut microbiota in advancing personalized medicine
Published 2023“…Ongoing extensive research in the field of gut microbiota (GM) has highlighted the crucial role of gut-dwelling microbes in human health. …”
Get full text
Get full text
Article -
29
Gut bacteria require neutrophils to promote mammary tumorigenesis
Published 2015“…These data demonstrate that host neutrophil-associated immune responses to intestinal tract microbes significantly impact cancer progression in distal tissues such as mammary glands, and identify gut microbes as novel targets for extra-intestinal cancer therapy.…”
Get full text
Get full text
Article -
30
Gut bacterial metabolites modulate endoplasmic reticulum stress
Published 2021“…Conclusions Our study identified novel links between classes of gut microbe-derived metabolites and the ER stress response, suggesting the potential for these metabolites to contribute to gut ER homeostasis and providing insight into the molecular mechanisms by which gut microbes impact intestinal epithelial cell homeostasis.…”
Get full text
Article -
31
The influence of the gut microbiome on BCG-induced trained immunity
Published 2021“…Roseburia is found to alter both trained immune responses and phenylalanine metabolism, revealing microbes and microbial products that may alter BCG-induced immunity. …”
Get full text
Article -
32
The influence of the gut microbiome on BCG-induced trained immunity
Published 2022“…Roseburia is found to alter both trained immune responses and phenylalanine metabolism, revealing microbes and microbial products that may alter BCG-induced immunity. …”
Get full text
Article -
33
The human gut bacterial genotoxin colibactin alkylates DNA
Published 2020“…Our findings reveal a potential biomarker for colibactin exposure and provide mechanistic insights into how a gut microbe may contribute to colorectal carcinogenesis.…”
Get full text
Article -
34
-
35
A review on health benefits and processing of tempeh with outlines on its functional microbes
Published 2024“…Consumption of tempeh has been linked to various health advantages including antidiabetic effects, cholesterol-lowering properties, improved cognitive function, antitumor and anticancer properties, anti-aging effects and improved gut health as well as reduced risk of cardiovascular disease. …”
Get full text
Article -
36
Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation
Published 2021“…Abstract Background The gut microbiome is altered in patients with inflammatory bowel disease, yet how these alterations contribute to intestinal inflammation is poorly understood. …”
Get full text
Article -
37
Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation
Published 2022“…Abstract Background The gut microbiome is altered in patients with inflammatory bowel disease, yet how these alterations contribute to intestinal inflammation is poorly understood. …”
Get full text
Article -
38
The evolution of mutualism in gut microbiota via host epithelial selection
Published 2012“…The human gut harbours a large and genetically diverse population of symbiotic microbes that both feed and protect the host. …”
Journal article -
39
Social networks strongly predict the gut microbiota of wild mice
Published 2021“…The mammalian gut teems with microbes, yet how hosts acquire these symbionts remains poorly understood. …”
Journal article -
40
Gut bacterial metabolism contributes to host global purine homeostasis
Published 2024“…Thus, gut microbes are important drivers of host global purine homeostasis and serum UA levels, and gut bacterial catabolism of purines may represent a mechanism by which gut bacteria influence health.…”
Get full text
Journal Article