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NASH-associated gut microbiome in human microbiota-associated NAFLD mouse model
Published 2023“…Subsequently, we compared the composition and diversities of the humanized gut microbiome resulting from different diets, revealing key microbes involved in NAFLD pathogenesis and their dynamics in the gut microbiome. …”
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Final Year Project (FYP) -
62
High-throughput amplicon sequencing of gut microbiome sea cucumber in Pahang, Malaysia
Published 2023“…The purpose of this study is to identify the gut microbiome of the sea cucumber from Stichopus ocellatus species. …”
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Conference or Workshop Item -
63
Meta-analysis of gut microbiome studies identifies disease-specific and shared responses
Published 2018“…Here we introduce the MicrobiomeHD database, which includes 28 published case-control gut microbiome studies spanning ten diseases. We perform a cross-disease meta-analysis of these studies using standardized methods. …”
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64
Unravelling the gut microflora landscape of broilers by high-throughput next generation sequencing
Published 2015“…Normal gut microflora plays an important function in nutrient absorption, feed digestion and modulation of immune response in the birds. …”
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Conference or Workshop Item -
65
CRISPR-Cas spacer acquisition is a rare event in human gut microbiome
Published 2025“…Host-parasite relationships drive the evolution of both parties. In microbe-phage dynamics, CRISPR functions as an adaptive defense mechanism, updating immunity via spacer acquisition. …”
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Journal Article -
66
Machine learning aided construction of the quorum sensing communication network for human gut microbiota
Published 2022“…Conventionally, a small number of QS entries are collected for specific microbes, which is far from being able to fully depict communication-based complex microbial interactions in human gut microbiota. …”
Journal article -
67
The scent of symbiosis : gut bacteria may affect social interactions in leaf-cutting ants
Published 2020“…Although nestmate recognition has undergone a thorough exploration during the last four decades, few studies have investigated the putative role of gut microbes. Here, we integrated 16S rRNA-based microbial community profiling, chemical and behavioural approaches to test whether gut microbes affect nestmate recognition in Acromyrmex echinatior leaf-cutting ants. …”
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Journal Article -
68
An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii
Published 2024“…Crosstalk of microbes with human gut epithelia and immune cells is crucial for gut health. …”
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Article -
69
Application of bacterial ligninase enzymes from rynchophorus ferrugineus’s gut consortium in agropulp biodelignification
Published 2018“…The results showed that the gut microbes were solely able to degrade lignin with 30 to 60% in OPL and CG respectively, in which the highest delignification is obtained by the combination of all species. …”
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Thesis -
70
Gut dysbiosis and intestinal barrier dysfunction: Potential explanation for early-onset colorectal cancer
Published 2021“…This review explains the potential role of the interaction among host factors, gut microenvironment, and gut microbiota, which may provide an answer to EOCRC.…”
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71
Metabolomics analysis of bacterial interactions with the environment : perspective from human gut and heavy metal stress
Published 2018“…Particularly, there are approximately 100 trillion microbes residing in the human gut and they are linked with health and disease. …”
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Thesis -
72
Regional and global changes in TCRalphabeta T cell repertoires in the gut are dependent upon the complexity of the enteric microflora.
Published 2010“…The repertoire of gut associated T cells is shaped by exposure to microbes, including the natural enteric microflora. …”
Journal article -
73
Maternal transmission gives way to social transmission during gut microbiota assembly in wild mice
Published 2023“…<p><strong>Background</strong> The mammalian gut microbiota influences a wide array of phenotypes which are relevant to fitness, yet knowledge about the transmission routes by which gut microbes colonise hosts in natural populations remains limited. …”
Journal article -
74
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes
Published 2023“…<p>Musculoskeletal diseases affect up to 20% of adults worldwide. The gut microbiome has been implicated in inflammatory conditions, but large-scale metagenomic evaluations have not yet traced the routes by which immunity in the gut affects inflammatory arthritis. …”
Journal article -
75
Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain
Published 2017“…<strong>Background:</strong> Cross-sectional studies suggest that the microbes in the human gut have a role in obesity by influencing the human body’s ability to extract and store calories. …”
Journal article -
76
Links between bacteria derived from penguin guts and deposited guano and the surrounding soil microbiota
Published 2018“…However, most research attention to date has focused separately on the penguin gut microbiota (via cloacal/guano samples) and the terrestrial soil microbiota, and any relationship between them has yet to be established. …”
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The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice
Published 2021“…Results: By comparing publicly available liver transcriptomics data from conventional vs. germ-free mice, we identified pregnane X receptor (PXR, NR1I2) transcriptional activity as strongly affected by the absence of gut microbes. Microbiota depletion using antibiotics in Pxr+/+ vs Pxr-/- C57BL/6J littermate mice followed by hepatic transcriptomics revealed that most microbiota-sensitive genes were PXR-dependent in the liver in males, but not in females. …”
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Journal Article -
79
Postnatal prebiotic supplementation in rats affects adult anxious behaviour, hippocampus electrophysiology, metabolomics and gut microbiota
Published 2021“…The study also suggests that early-life prebiotic intake may affect host brain function through the reduction of stress-related gut bacteria rather than increasing the proliferation of beneficial microbes.…”
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80
Onset of hypertriglyceridemia in relation to dietary intake, gut microbiome and metabolomics signatures among home dwelling elderly
Published 2020“…The human gut is home for plethora of microbes including prokaryotic, eukaryotic and other microorganisms. …”
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Article