A randomised controlled trial of dietary improvement for adults with major depression (the ‘SMILES’ trial) by Felice N. Jacka, Adrienne O’Neil, Rachelle Opie, Catherine Itsiopoulos, Sue Cotton, Mohammedreza Mohebbi, David Castle, Sarah Dash, Cathrine Mihalopoulos, Mary Lou Chatterton, Laima Brazionis, Olivia M. Dean, Allison M. Hodge, Michael Berk

Get full text

Phytochrome-Mediated Light Perception Affects Fruit Development and Ripening Through Epigenetic Mechanisms by Ricardo Bianchetti, Nicolas Bellora, Luis A. de Haro, Rafael Zuccarelli, Daniele Rosado, Luciano Freschi, Magdalena Rossi, Luisa Bermudez, Luisa Bermudez

Get full text

Coupling Remote Sensing Data and AquaCrop Model for Simulation of Winter Wheat Growth under Rainfed and Irrigated Conditions in a Mediterranean Environment by Marie Therese Abi Saab, Razane El Alam, Ihab Jomaa, Sleiman Skaf, Salim Fahed, Rossella Albrizio, Mladen Todorovic

Get full text

Monoclonal antibody BTT1023 targeting vascular adhesion protein 1 for treating primary sclerosing cholangitis: BUTEO single-arm Phase II trial by Katherine Arndtz, Yung-Yi Chen, Anna Rowe, Victoria Homer, Amanda Kirkham, Jessica Douglas-Pugh, Daniel Slade, Douglas Thorburn, Eleanor Barnes, Guruprasad Aithal, Philip Newsome, David Smith, David Adams, Christopher Weston, Gideon Hirschfield

“…Funding: This project was funded by the Efficacy and Mechanism Evaluation programme, a Medical Research Council and National Institute for Health Research (NIHR) partnership. …”
Get full text

Estimates of remote sensing retrieval errors by the GRASP algorithm: application to ground-based observations, concept and validation by M. E. Herrera, O. Dubovik, B. Torres, T. Lapyonok, D. Fuertes, A. Lopatin, P. Litvinov, C. Chen, J. A. Benavent-Oltra, J. L. Bali, P. R. Ristori

Get full text

Evaluating the effectiveness of a multifaceted intervention to reduce low-value care in adults hospitalized following trauma: a protocol for a pragmatic cluster randomized controll... by Lynne Moore, Mélanie Bérubé, Amina Belcaid, Alexis F. Turgeon, Monica Taljaard, Robert Fowler, Natalie Yanchar, Éric Mercier, Jérôme Paquet, Henry Thomas Stelfox, Patrick Archambault, Simon Berthelot, Jason R. Guertin, Barbara Haas, Noah Ivers, Jeremy Grimshaw, Alexandra Lapierre, Yongdong Ouyang, Michael Sykes, Holly Witteman, Paule Lessard-Bonaventure, Belinda Gabbe, François Lauzier, The Canadian Traumatic Brain Injury Research Consortium (CTRC)

Get full text

Peri-Operative Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Cardiac and Thoracic Surgery: A RAND/UCLA Appropriateness Method Consensus Study by Sonia Bianchini, Laura Nicoletti, Sara Monaco, Erika Rigotti, Agnese Corbelli, Annamaria Colombari, Cinzia Auriti, Caterina Caminiti, Giorgio Conti, Maia De Luca, Daniele Donà, Luisa Galli, Silvia Garazzino, Alessandro Inserra, Stefania La Grutta, Laura Lancella, Mario Lima, Andrea Lo Vecchio, Gloria Pelizzo, Nicola Petrosillo, Giorgio Piacentini, Carlo Pietrasanta, Nicola Principi, Matteo Puntoni, Alessandro Simonini, Simonetta Tesoro, Elisabetta Venturini, Annamaria Staiano, Fabio Caramelli, Gaetano Domenico Gargiulo, Susanna Esposito, on behalf of the Peri-Operative Prophylaxis in Neonatal and Paediatric Age (POP-NeoPed) Study Group

Get full text

Natural and hybrid immunity following four COVID-19 waves: A prospective cohort study of mothers in South Africa by Heather J. Zar, Rae MacGinty, Lesley Workman, Maresa Botha, Marina Johnson, Adam Hunt, Tiffany Burd, Mark P. Nicol, Stefan Flasche, Billy J. Quilty, David Goldblatt

“…MPN is supported by an Australian National Health and Medical Research Council Investigator Grant (APP1174455). …”
Get full text

Efficacy and safety of cosibelimab, an anti-PD-L1 antibody, in metastatic cutaneous squamous cell carcinoma by Jayesh Desai, Stephane Dalle, Jermaine Coward, Daniel Brungs, Andrew Mant, Margaret McGrath, Andrea Tazbirkova, Piotr Koralewski, Iwona Lugowska, Arunee Dechaphunkul, Virote Sriuranpong, James Oliviero, Philip Clingan, Rahul Ladwa, Eva Muñoz-Couselo, Henri Montaudié, Miguel-Ángel Berciano-Guerrero, Dean Laurence Harris, Susan Arnold, Samuel Fourie, Andriy Kurochkin, Daniel R Malan, Vinay Sharma, Hong Shue, Chaiyut Charoentum, Oleksandr Dudnichenko

Get full text

Cord blood lipid correlation network profiles are associated with subsequent attention-deficit/hyperactivity disorder and autism spectrum disorder symptoms at 2 years: a prospectiv... by Kristina Vacy, Sarah Thomson, Archer Moore, Alex Eisner, Sam Tanner, Cindy Pham, Richard Saffrey, Toby Mansell, David Burgner, Fiona Collier, Peter Vuillermin, Martin O’Hely, Wah Chin Boon, Peter Meikle, Satvika Burugupalli, Anne-Louise Ponsonby, Mimi L.K. Tang, Lawrence Gray, Sarath Ranganathan, Peter Sly, Jochen Mueller, Terry Dwyerm, John Carlin

“…Subsequent funding was secured from the Minderoo Foundation, the European Union's Horizon 2020 research and innovation programme (ENDpoiNTs: No 825759), National Health and Medical Research Council of Australia (NHMRC) and Agency for Science, Technology and Research Singapore [APP1149047], The William and Vera Ellen Houston Memorial Trust Fund (via HOMER Hack), The Shepherd Foundation, The Jack Brockhoff Foundation, the Scobie & Claire McKinnon Trust, the Shane O'Brien Memorial Asthma Foundation, the Our Women Our Children's Fund Raising Committee Barwon Health, the Rotary Club of Geelong, the Ilhan Food Allergy Foundation, Geelong Medical and Hospital Benefits Association, Vanguard Investments Australia Ltd, the Percy Baxter Charitable Trust, and Perpetual Trustees.…”
Get full text

An Investigation of the Role of Common and Rare Variants in a Large Italian Multiplex Family of Multiple Sclerosis Patients by Nadia Barizzone, Rachele Cagliani, Chiara Basagni, Ferdinando Clarelli, Laura Mendozzi, Cristina Agliardi, Diego Forni, Martina Tosi, Elisabetta Mascia, Francesco Favero, Davide Corà, Lucia Corrado, Melissa Sorosina, Federica Esposito, Miriam Zuccalà, Domizia Vecchio, Maria Liguori, Cristoforo Comi, Giancarlo Comi, Vittorio Martinelli, Massimo Filippi, Maurizio Leone, Filippo Martinelli-Boneschi, Domenico Caputo, Manuela Sironi, Franca Rosa Guerini, Sandra D’Alfonso

Get full text

Positron emission tomography to image cerebral neuroinflammation in ischaemic stroke: a pilot study by Eszter Visi, Rainer Hinz, Martin Punter, Arshad Majid, Alexander Gerhard, Karl Herholz

“…Funding: This project was funded by the Efficacy and Mechanism Evaluation programme, a Medical Research Council and National Institute for Health Research (NIHR) partnership, and will be published in full in Efficacy and Mechanism Evaluation; Vol. 7, No. 1. …”
Get full text

Mucosal immune response after the booster dose of the BNT162b2 COVID-19 vaccineResearch in context by Lorenzo Azzi, Daniela Dalla Gasperina, Giovanni Veronesi, Mariam Shallak, Vittorio Maurino, Andreina Baj, Francesco Gianfagna, Pierpaolo Cavallo, Francesco Dentali, Lucia Tettamanti, Fabrizio Maggi, Lorenzo Stefano Maffioli, Angelo Tagliabue, Roberto Sergio Accolla, Greta Forlani

Get full text

SARS-CoV-2 spike antigen-specific B cell and antibody responses in pre-vaccination period COVID-19 convalescent males and females with or without post-covid condition by Marc-André Limoges, Akouavi Julite Irmine Quenum, Mohammad Mobarak Hussain Chowdhury, Fjolla Rexhepi, Mozhdeh Namvarpour, Sara Ali Akbari, Christine Rioux-Perreault, Madhuparna Nandi, Jean-François Lucier, Samuel Lemaire-Paquette, Lakshmanane Premkumar, Yves Durocher, André Cantin, Simon Lévesque, Simon Lévesque, Isabelle J. Dionne, Isabelle J. Dionne, Alfredo Menendez, Subburaj Ilangumaran, Hugues Allard-Chamard, Alain Piché, Sheela Ramanathan

Get full text

Genome-wide characterization of circulating metabolic biomarkers by Karjalainen, Minna K., Karthikeyan, Savita, Oliver-Williams, Clare, Sliz, Eeva, Allara, Elias, Fung, Wing Tung, Surendran, Praveen, Zhang, Weihua, Jousilahti, Pekka, Kristiansson, Kati, Salomaa, Veikko, Goodwin, Matt, Hughes, David A., Boehnke, Michael, Silva, Lilian Fernandes, Yin, Xianyong, Mahajan, Anubha, Neville, Matt J., van Zuydam, Natalie R., de Mutsert, Renée, Li-Gao, Ruifang, Mook-Kanamori, Dennis O., Demirkan, Ayse, Liu, Jun, Noordam, Raymond, Trompet, Stella, Chen, Zhengming, Kartsonaki, Christiana, Li, Liming, Lin, Kuang, Hagenbeek, Fiona A., Hottenga, Jouke Jan, Pool, René, Ikram, M. Arfan, van Meurs, Joyce, Haller, Toomas, Milaneschi, Yuri, Kähönen, Mika, Mishra, Pashupati P., Joshi, Peter K., Macdonald-Dunlop, Erin, Mangino, Massimo, Zierer, Jonas, Acar, Ilhan E., Hoyng, Carel B., Lechanteur, Yara T. E., Franke, Lude, Kurilshikov, Alexander, Zhernakova, Alexandra, Beekman, Marian, van den Akker, Erik B., Kolcic, Ivana, Polasek, Ozren, Rudan, Igor, Gieger, Christian, Waldenberger, Melanie, Asselbergs, Folkert W., Hayward, Caroline, Fu, Jingyuan, den Hollander, Anneke I., Menni, Cristina, Spector, Tim D., Wilson, James F., Lehtimäki, Terho, Raitakari, Olli T., Penninx, Brenda W. J. H., Esko, Tonu, Walters, Robin G., Jukema, J. Wouter, Sattar, Naveed, Ghanbari, Mohsen, van Dijk, Ko Willems, Karpe, Fredrik, McCarthy, Mark I., Laakso, Markku, Järvelin, Marjo-Riitta, Timpson, Nicholas J., Perola, Markus, Kooner, Jaspal S., Chambers, John Campbell, van Duijn, Cornelia, Slagboom, P. Eline, Boomsma, Dorret I., Danesh, John, Ala-Korpela, Mika, Butterworth, Adam S., Kettunen, Johannes

Get full text

The Effect of Using Different Fat Sources in Close-Up Diets on the Feed Consumption, Blood Parameters, Body Measurements and Performance of Holstein Dairy Calves by Mahmoodreza Amini, Abbas Ali Naserian, Reza Valizadeh, Essa Dirandeh

“…Diets were thoroughly mixed and fed to cows based on the recommendations of the US National Research Council (NRC, 2001). The experimental rations included: 1) Control diet without fat source (Ctrl), 2) Diet with palmitic fatty acid (SFA), and 3) Diet with safflower seed (UFA). …”
Get full text

Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization by Esther Clavero, José Manuel Sanchez-Maldonado, Angelica Macauda, Rob Ter Horst, Belém Sampaio-Marques, Artur Jurczyszyn, Alyssa Clay-Gilmour, Angelika Stein, Michelle A. T. Hildebrandt, Niels Weinhold, Gabriele Buda, Ramón García-Sanz, Waldemar Tomczak, Ulla Vogel, Andrés Jerez, Daria Zawirska, Marzena Wątek, Jonathan N. Hofmann, Stefano Landi, John J. Spinelli, Aleksandra Butrym, Abhishek Kumar, Joaquín Martínez-López, Sara Galimberti, María Eugenia Sarasquete, Edyta Subocz, Elzbieta Iskierka-Jażdżewska, Graham G. Giles, Malwina Rybicka-Ramos, Marcin Kruszewski, Niels Abildgaard, Francisco García Verdejo, Pedro Sánchez Rovira, Miguel Inacio da Silva Filho, Katalin Kadar, Małgorzata Razny, Wendy Cozen, Matteo Pelosini, Manuel Jurado, Parveen Bhatti, Marek Dudzinski, Agnieszka Druzd-Sitek, Enrico Orciuolo, Yang Li, Aaron D. Norman, Jan Maciej Zaucha, Rui Manuel Reis, Miroslaw Markiewicz, Juan José Rodríguez Sevilla, Vibeke Andersen, Krzysztof Jamroziak, Kari Hemminki, Sonja I. Berndt, Vicent Rajkumar, Grzegorz Mazur, Shaji K. Kumar, Paula Ludovico, Arnon Nagler, Stephen J. Chanock, Charles Dumontet, Mitchell J. Machiela, Judit Varkonyi, Nicola J. Camp, Elad Ziv, Annette Juul Vangsted, Elizabeth E. Brown, Daniele Campa, Celine M. Vachon, Mihai G. Netea, Federico Canzian, Asta Försti, Juan Sainz

Get full text

HEALTH IMPACTS OF AIR POLLUTION AND CLIMATE CHANGE by Adil Zareef

“…On Friday 8th October 2021, the United Nations (UN) Human Rights Council in a “historic breakthrough” declared access to an environment without pollution as a fundamental human right. …”
Get full text

The contribution of homestead pond fish culture to household food security and dietary diversity in central coast of a developing country by M. Belal Hossain, F.H. Pingki, M. Sultana, N.M. Salim, M.M. Islam, A.F.M. Arifur Rahman, Bilal Ahamad Paray, Takaomi Arai

Get full text

Case Report: Consistent disease manifestations with a staggered time course in two identical twins affected by adenosine deaminase 2 deficiency by Federica Barzaghi, Maria Pia Cicalese, Maria Pia Cicalese, Maria Pia Cicalese, Matteo Zoccolillo, Immacolata Brigida, Matteo Barcella, Matteo Barcella, Ivan Merelli, Claudia Sartirana, Monica Zanussi, Valeria Calbi, Maria Ester Bernardo, Maria Ester Bernardo, Maria Ester Bernardo, Francesca Tucci, Maddalena Migliavacca, Fabio Giglio, Matteo Doglio, Daniele Canarutto, Daniele Canarutto, Daniele Canarutto, Francesca Ferrua, Giulia Consiglieri, Giulia Consiglieri, Giulia Prunotto, Giulia Prunotto, Francesco Saettini, Sonia Bonanomi, Patrizia Rovere-Querini, Patrizia Rovere-Querini, Giulia Di Colo, Giulia Di Colo, Tatiana Jofra, Georgia Fousteri, Federica Penco, Marco Gattorno, Michael S. Hershfield, Lucia Bongiovanni, Maurilio Ponzoni, Maurilio Ponzoni, Sarah Marktel, Raffaella Milani, Jacopo Peccatori, Fabio Ciceri, Fabio Ciceri, Alessandra Mortellaro, Alessandro Aiuti, Alessandro Aiuti, Alessandro Aiuti

Get full text