-
1
Effects of ICI 182,780, an ERα and ERβ antagonist, and G-1, a GPER agonist, on autophagy in breast cancer cells
Published 2020-04-01“…ABSTRACT Objective To investigate if ICI 182,780 (fulvestrant), a selective estrogen receptor alpha/beta (ERα/ERβ) antagonist, and G-1, a selective G-protein-coupled receptor (GPER) agonist, can potentially induce autophagy in breast cancer cell lines MCF-7 and SKBr3, and how G-1 affects cell viability. …”
Get full text
Article -
2
An Immune-Related Gene Prognostic Index for Triple-Negative Breast Cancer Integrates Multiple Aspects of Tumor-Immune Microenvironment
Published 2021-10-01“…With the significantly improved survival rate of TNBC patients treated with ICI therapies, a biomarker integrating multiple aspects of TIME may have prognostic value for improving the efficacy of ICI therapy. …”
Get full text
Article -
3
Subzero saline chilling with or without prechilling in icy water improved chilling efficiency and meat tenderness of broiler carcasses
Published 2023-11-01“…Color (L*, a*, and b*) values were evaluated on both breast skin and skinless breast surfaces. Meat tenderness was evaluated using the breast fillets after overnight storage and cooking to an internal temperature of 76°C. …”
Get full text
Article -
4
A real‐world study of immune checkpoint inhibitors in advanced triple‐negative breast cancer
Published 2023-06-01“…Abstract Background Triple‐negative breast cancer (TNBC) is the most aggressive type of breast cancer. …”
Get full text
Article -
5
Serotonin after β-Adrenoreceptors’ Exposition: New Approaches for Personalized Data in Breast Cancer Cells
Published 2021-09-01“…Previously, our group reported that β-adrenergic drugs (ICI 118,551, isoprenaline, and propranolol) influence the proliferation of breast cancer cells (MCF-7 cells) and their inherent production of adrenaline. …”
Get full text
Article -
6
Hope and Hype around Immunotherapy in Triple-Negative Breast Cancer
Published 2023-05-01Subjects: “…triple-negative breast cancer…”
Get full text
Article -
7
Updates in combined approaches of radiotherapy and immune checkpoint inhibitors for the treatment of breast cancer
Published 2022-10-01Subjects: “…immune checkpoint inhibitors (ICI)…”
Get full text
Article -
8
Next generation immuno-oncology tumor profiling using a rapid, non-invasive, computational biophysics biomarker in early-stage breast cancer
Published 2023-04-01“…BackgroundImmuno-oncology (IO) therapies targeting the PD-1/PD-L1 axis, such as immune checkpoint inhibitor (ICI) antibodies, have emerged as promising treatments for early-stage breast cancer (ESBC). …”
Get full text
Article -
9
Facts and Perspectives: Implications of tumor glycolysis on immunotherapy response in triple negative breast cancer
Published 2023-01-01Subjects: “…triple negative breast cancer (TNBC)…”
Get full text
Article -
10
PD-L1 expression as biomarker of efficacy of PD-1/PD-L1 checkpoint inhibitors in metastatic triple negative breast cancer: A systematic review and meta-analysis
Published 2023-03-01Subjects: “…breast cancer…”
Get full text
Article -
11
Optimal response to tislelizumab plus chemotherapy in metastatic triple-negative breast cancer: a case report and literature review
Published 2024-03-01Subjects: “…metastatic triple negative breast cancer (mTNBC)…”
Get full text
Article -
12
ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid
Published 2023-02-01Subjects: “…breast cancer…”
Get full text
Article -
13
-
14
Imunoterapia no cancro de mama triplo-negativo: o papel dos inibidores de checkpoint imunológico
Published 2022-11-01Subjects: “…Triple-negative breast cancer…”
Get full text
Article -
15
Advances in immunotherapy for triple-negative breast cancer
Published 2023-09-01“…This review highlights the unique tumor microenvironment of TNBC and integrates and analyzes the advances in ICI therapy. It also discusses strategies for the combination of ICIs with chemotherapy, radiation therapy, targeted therapy, and emerging treatment methods such as nanotechnology, ribonucleic acid vaccines, and gene therapy. …”
Get full text
Article -
16
Immunotherapy Treatment for Triple Negative Breast Cancer
Published 2021-08-01“…Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes of breast cancer and has dismal prognosis. …”
Get full text
Article -
17
Opportunities for Antigen Discovery in Metastatic Breast Cancer
Published 2020-10-01“…Immune checkpoint inhibitor-based immunotherapy (ICI) of breast cancer is currently efficacious in a fraction of triple negative breast cancers (TNBC) as these cancers generally carry high tumor mutation burden (TMB) and show increased tumor infiltration by CD8+ T cells. …”
Get full text
Article -
18
Inhibition of the PI3K/mTOR Pathway in Breast Cancer to Enhance Response to Immune Checkpoint Inhibitors in Breast Cancer
Published 2021-05-01“…Objectives: Inhibition of the PI3K/mTOR pathway suppresses breast cancer (BC) growth, enhances anti-tumor immune responses, and works synergistically with immune checkpoint inhibitors (ICI). …”
Get full text
Article -
19
-
20
Immunological barriers to immunotherapy in primary and metastatic breast cancer
Published 2021-08-01“…Patients with breast cancer obtain limited clinical benefits from immune checkpoint inhibitors (ICIs), pointing to the existence of multiple immunological alterations that cannot be simultaneously normalized with immunotherapy. …”
Get full text
Article