Development of Rifampicin-Indocyanine Green-Loaded Perfluorocarbon Nanodroplets for Photo-Chemo-Probiotic Antimicrobial Therapy by Kuang-Hung Hsiao, Chun-Ming Huang, Chun-Ming Huang, Yu-Hsiang Lee, Yu-Hsiang Lee

“…Furthermore, the RIPNDs were able to induce fermentation of S. epidermidis but not P. acnes, indicating that the RIPNDs may serve as a selective fermentation initiator for the target probiotics. …”
Get full text

Toll-like receptor 2 and Toll-like receptor 4 exhibit distinct regulation of cancer cell stemness mediated by cell death-induced high-mobility group box 1Research in context by Xuelian Chen, Fang Cheng, Yanfang Liu, Lirong Zhang, Lian Song, Xiaojie Cai, Tao You, Xin Fan, Dongqing Wang, Aihua Gong, Haitao Zhu

“…Methods: Using the Millicell system as an in vitro co-culture model, we performed quantitative reverse transcriptase-polymerase chain reaction, western blot and sphere forming ability analyses to access the effect of dying-cell-derived HMGB1 on CD133+ cancer cell stemness in vitro and in vivo. …”
Get full text

How to diagnose equal opportunities between women and men in organizations by Amaia Lusa, Carme Martínez, Maria Dolors Calvet, Olga Pons, Marta Tura

“…Despite the great effort made by governments and the progress of laws, gender discrimination still exists in family, social, cultural, political and economic spheres. Even today, it is rare to find women at the top level in companies. …”
Get full text

Repositioning Trimebutine Maleate as a Cancer Treatment Targeting Ovarian Cancer Stem Cells by Heejin Lee, Oh-Bin Kwon, Jae-Eon Lee, Yong-Hyun Jeon, Dong-Seok Lee, Sang-Hyun Min, Jun-Woo Kim

“…This study evaluated the effect of trimebutine maleate (TM) targeting ovarian CSCs, using A2780-SP cells acquired by a sphere culture of A2780 epithelial ovarian cancer cells. …”
Get full text

β-Tubulin Isotype, TUBB4B, Regulates The Maintenance of Cancer Stem Cells by Dhrishya Dharmapal, Dhrishya Dharmapal, Athira Jyothy, Athira Jyothy, Amrutha Mohan, Amrutha Mohan, P. G. Balagopal, Nebu Abraham George, Paul Sebastian, Tessy Thomas Maliekal, Suparna Sengupta

“…Since membrane trafficking proteins have been shown to be essential for the localization of critical proteins supporting CSCs, we investigated the role of TUBB4B, a probable membrane trafficking protein that was found to be overexpressed in the membranes of stem cell enriched cultures, in sustaining CSCs in oral cancer. Here, we show that the knockdown of TUBB4B downregulates the expression of pluripotency markers, depletes ALDH1A1+ population, decreases in vitro sphere formation, and diminishes the tumor initiation potential in vivo. …”
Get full text

Anti-tumour efficacy of human mesenchymal stem cell expressing trail on lung cancer cell lines-derived cancer stem cell by Shaik M Fakiruddin, Shaik Ahmad Kamal

“…It was observed that the sorted CD133+ population strongly exhibited the characteristics of CSCs based on their bigger sphere size detected in an anchorage independent culture, significantly higher number of colonies, and expression of aldehyde dehydrogenase (ALDH), when compared to the non-CSC’s control (CD133-). …”
Get full text

Combination ‘New Sincerity’ in Lexicographic Aspect by T. V. Leontyeva, A. V. Shchetinina

“…It is noted that expressions built according to the “new + noun” model: new sincerity, new reality, new sociality, new normality, new romance, etc., include the second component, which names the phenomenon of socio-cultural or moral spheres, which has long been known by native speakers. …”
Get full text

Modernization of social relations on the basis of social responsibility by Maryna Deych

“…In general, the results of research and publications indicate a lack of people opinions about the manifestation of social responsibility in the various spheres of life. …”
Get full text

The Russian revolution of 1917 through the prism of demographic modernization by Boris Mironov

“…People who were actively and consciously drawn into the demographic transition, who had been transformed psychologically, mentally, and culturally, were also receptive to innovation in the social, political, cultural, and economic spheres and were the most prepared for and willing to refashion social life on a bourgeois-democratic basis. …”
Get full text

Discourses in science fiction movies: science teaching and the production of meanings in the socio-environmental perspective by Júlio César David Ferreira, Roberto Gonçalves Barbosa

“…These discourses, in their various social spheres and conditions of production, are manifested in the teaching and learning relations of science education. …”
Get full text

Educational Research: An Ethical Commitment to the Promotion of the Quality of Life and the Respect for Human Dignity by Horacio Ademar Ferreyra, Georgia Blanas de Marengo

“…The development of research and application of results in all spheres of human activity is the basis of the "information economy" and "knowledge societies ". …”
Get full text

DIALOGIZATION AS A RESOURCE OF LANGUAGE LEARNING IN THE CONTEXT OF UPDATING TRADITIONAL TEACHING METHODS by BONDARENKO, N.V, VASKIVSKA, O.Y, KOSIANCHUK, S.V

“…The lack of alternative to the dialogization of the educational process has been proved; the need to reboot traditional reproductive methods of language teaching based on the dialogization of the educational process; the essence, role, place are theoretically substantiated, ways and means of dialogization of language teaching as a tool for updating traditional reproductive teaching methods are determined; the proven ways of functional enrichment of traditional reproductive methods of language teaching with new modern effective methods are indicated. The importance of a broad understanding of the dialogue, which scientists classify as human studies, is emphasized; an objective need to expand the range of communication between a teacher and pupils, to fill it with meaningful meaning for both sides; the differences between ordinary and educational dialogue are characterized; the main conditions for the dialogization of language teaching are identified and described, namely: the use of personality-oriented, competence-based and activity-based approaches; approval of subject-subject relations in the educational process; building training on a socio-cultural, textual and question-and-answer basis; introduction into the educational process of modern dialogical methods, elements of heuristic and problem learning; dialogical transformation of traditional reproductive teaching methods; widespread use of interactive forms of education. …”
Get full text

adipoSIGHT in Therapeutic Response: Consequences in Osteosarcoma Treatment by Banani Kundu, Virginia Brancato, Joaquim Oliveira, Vitor M. Correlo, Rui L. Reis, Subhas C. Kundu

“…Staining with a cell tracker allows real-time microscopic monitoring of the cell arrangement within the sphere. Cell–cell interaction is investigated by means of E-cadherin expression. …”
Get full text

Ethnic Differentials of Religiosity in Iran by Yaghoob Foroutan

“…The literature review indicated that while a substantially wide range of ethnic groups is widespread throughout the country, their religious attitude has not been sufficiently studied in the existing literature particularly from comparative perspectives. …”
Get full text

The Transfer of Religiousness in the Family from Parents to Children: An Analytical Review of Studies by Konstantin S. Divisenko, Alexei E. Belov, Olga V. Divisenko

“…The growing interest towards studying the impact of religion on various spheres of social life is reflected in quite large corpus of academic publications. …”
Get full text

VERBAL REPRESENTATION OF THE CONCEPT OF POLITENESS AND ITS SPECIFICS IN RUSSIAN AND MODERN HEBREW by Pishchalnikova Vera Anatolyevna, Kiselev Valeriy Vadimovich

“…The authors believe that this could be the indication of certain universal types of relations between word's meaning components.…”
Get full text

The concept of Κένωσις in Philippians 2:6–7 and its contextual application in Africa by John A. Ottuh

“…From observation, leadership in various spheres of the society in Africa, such as ecclesiastical, political and traditional, lack selflessness as indicated in this article. …”
Get full text

Exploring Lessons from Soviet Diplomacy and Western Allied Cooperation in World War II by V. O. Pechatnov

“…It also acknowledges dissenting voices in Anglo-American political spheres who advocated for a more equitable relationship with the USSR. …”
Get full text

Uso de Plantas com Fins Medicinais no Município de Barra – BA by Antonia Mirian Nogueira de Moura Guerra, Priscila Santos Silva, Hélen Tamares Santos de Sá, Deyse Silva dos Santos, Aline Carla de Medeiros, Debora Cristina Coelho

“…Note that the residents are in possession of a vast empirical knowledge related to ethnobotany and climatic conditions related to the management of the flora of the region and the use of medicinal plants for therapeutic purposes is striking, showing that the popular use of medicinal plants is inserted significantly in the social and cultural spheres of the community, which will ensure the perpetuation of customs among the next generations.…”
Get full text

Un ensemble funéraire de l’Antiquité tardive à dépôt atypique d’âne à Woippy (Moselle) by Gaël Brkojewitsch, Olivier Putelat

“…The material culture is not abundant and, on average, the graves contain 3.5 objects. …”
Get full text