Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease by Connor A. Emdin, Amit V. Khera, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Krishna Aragam, Mary Haas, Alexander Bick, Seyedeh M. Zekavat, Akihiro Nomura, Diego Ardissino, James G. Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J. Bown, Nilesh J. Samani, Usman Baber, Jeanette Erdmann, Namrata Gupta, John Danesh, Daniel Chasman, Paul Ridker, Joshua Denny, Lisa Bastarache, Judith H. Lichtman, Gail D’Onofrio, Jennifer Mattera, John A. Spertus, Wayne H.-H. Sheu, Kent D. Taylor, Bruce M. Psaty, Stephen S. Rich, Wendy Post, Jerome I. Rotter, Yii-Der Ida Chen, Harlan Krumholz, Danish Saleheen, Stacey Gabriel, Sekar Kathiresan

Get full text

Radio Astronomy by Dreher, John H., Burke, Bernard F., Carilli, Christopher, Hewitt, Jacqueline N., Langston, Glen, Heflin, Michael B., Connor, Samuel, Dhawan, Vivek, Staelin, David H., Shao, Michael, Barrett, John W., Clark, Lloyd D., Jr., Holm, R. Walter, Kelly, Matthew J., Hines, Braden E., Rosenkranz, Philip W., Briancon, Alain C., Bonanni, Pierino G., Gasiewski, Albin J., de Jager, Gerhard, Malvar, Henrique S., Bartlett, Gregory J., Shapiro, Jerome S., Szabo, Bernard I., Arias, Tomas A., Hammerschlag, Roeland V., Moores, John D., Preisig, James C., Wornell, Gregory W.

Get full text

Radio Astronomy by Dreher, John H., Burke, Bernard F., Carilli, Christopher, Hewitt, Jacqueline N., Langston, Glen, Heflin, Michael B., Connor, Samuel, Dhawan, Vivek, Barrett, John W., Staelin, David H., Shao, Michael, Hines, Braden E., Kim, Edward J., Rosenkranz, Phillip W., Kuo, Charlene C., Bonanni, Pierino G., Gasiewski, Albin J., Zanciewicz, Gregory J., Malvar, Henrique S., Brofferio, Sergio, Preisig, James C., Shapiro, Jerome S., Szabo, Bernard I., Wornell, Gregory W., Cheung, Shiufun, Irving, William I., Lum, Gordon M., Medard, Muriel, Arias, Tomas A., Hammerschlag, Roeland V., Eikenberry, Stephen S.

Get full text

Renal Denervation as a Complementary Treatment Option for Uncontrolled Arterial Hypertension: A Situation Assessment by Max Wagener, Eamon Dolan, Samer Arnous, Joseph Galvin, Andrew W. Murphy, Ivan Casserly, Joseph Eustace, Stephen O’Connor, Charles McCreery, James Shand, Catherine Wall, Saijad Matiullah, Faisal Sharif

Get full text

Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans by Peterson, Anthony J., Menheniott, Trevelyan R., O'Connor, Louise, Walduck, Anna K., Fox, James G., Kawakami, Kazuyuki, Minamoto, Toshinari, Ong, Eng Kok, Wang, Timothy C., Judd, Louise M., Giraud, Andrew S.

Get full text
Get full text

Combined Turmeric, Vitamin C, and Vitamin D Ready-to-Drink Supplements Reduce Upper Respiratory Illness Symptoms and Gastrointestinal Discomfort in Elite Male Football Players by David J. Clayton, Ross Burbeary, Connor Parker, Ruth M. James, Chris Saward, Eleanor L. Procter, William J. A. Mode, Carla Baker, John Hough, Neil C. Williams, Harry Rossington, Ian Varley

Get full text

Microbiomes of Various Maternal Body Systems Are Predictive of Calf Digestive Bacterial Ecology by Connor E. Owens, Haley G. Huffard, Alexandra I. Nin-Velez, Jane Duncan, Chrissy L. Teets, Kristy M. Daniels, Alan D. Ealy, Robert E. James, Katharine F. Knowlton, Rebecca R. Cockrum

Get full text

Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication. by Adam J Ericsen, Michael Lauck, Mariel S Mohns, Sarah R DiNapoli, James P Mutschler, Justin M Greene, Jason T Weinfurter, Gabrielle Lehrer-Brey, Trent M Prall, Samantha M Gieger, Connor R Buechler, Kristin A Crosno, Eric J Peterson, Matthew R Reynolds, Roger W Wiseman, Benjamin J Burwitz, Jacob D Estes, Jonah B Sacha, Thomas C Friedrich, Jason M Brenchley, David H O'Connor

Get full text

Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer by Dowling, Catríona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Tríona Ní

Get full text

Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2. by Dong-Hoon Chung, Colleen B Jonsson, Nichole A Tower, Yong-Kyu Chu, Ergin Sahin, Jennifer E Golden, James W Noah, Chad E Schroeder, Julie B Sotsky, Melinda I Sosa, Daniel E Cramer, Sara N McKellip, Lynn Rasmussen, E Lucile White, Connie S Schmaljohn, Justin G Julander, Jeffrey M Smith, Claire Marie Filone, John H Connor, Yasuteru Sakurai, Robert A Davey

Get full text

A Sensitive Search for Supernova Emission Associated with the Extremely Energetic and Nearby GRB 221009A by Gokul P. Srinivasaragavan, Brendan O’Connor, S. Bradley Cenko, Alexander J. Dittmann, Sheng Yang, Jesper Sollerman, G. C. Anupama, Sudhanshu Barway, Varun Bhalerao, Harsh Kumar, Vishwajeet Swain, Erica Hammerstein, Isiah Holt, Shreya Anand, Igor Andreoni, Michael W. Coughlin, Simone Dichiara, Avishay Gal-Yam, M. Coleman Miller, Jaime Soon, Roberto Soria, Joseph Durbak, James H. Gillanders, Sibasish Laha, Anna M. Moore, Fabio Ragosta, Eleonora Troja

Get full text

Study protocol for family model diabetes self-management education with Marshallese participants in faith-based organizations by Pearl A. McElfish, Sheldon Riklon, Rachel S. Purvis, Christopher R. Long, Holly C. Felix, Jonell S. Hudson, Derek Alik, Joseph Henske, Dinesh Edem, Gail O'Connor, Janine Boyers, Brett Rowland, James P. Selig

Get full text

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity by Jacqueline H. L. Fok, Antonio Ramos-Montoya, Mercedes Vazquez-Chantada, Paul W. G. Wijnhoven, Valeria Follia, Neil James, Paul M. Farrington, Ankur Karmokar, Sophie E. Willis, Jonathan Cairns, Jenni Nikkilä, David Beattie, Gillian M. Lamont, M. Raymond V. Finlay, Joanne Wilson, Aaron Smith, Lenka Oplustil O’Connor, Stephanie Ling, Stephen E. Fawell, Mark J. O’Connor, Simon J. Hollingsworth, Emma Dean, Frederick W. Goldberg, Barry R. Davies, Elaine B. Cadogan

Get full text

Sleep-disordered breathing and mortality: a prospective cohort study. by Naresh M Punjabi, Brian S Caffo, James L Goodwin, Daniel J Gottlieb, Anne B Newman, George T O'Connor, David M Rapoport, Susan Redline, Helaine E Resnick, John A Robbins, Eyal Shahar, Mark L Unruh, Jonathan M Samet

Get full text

Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial. by Paul T Edlefsen, Morgane Rolland, Tomer Hertz, Sodsai Tovanabutra, Andrew J Gartland, Allan C deCamp, Craig A Magaret, Hasan Ahmed, Raphael Gottardo, Michal Juraska, Connor McCoy, Brendan B Larsen, Eric Sanders-Buell, Chris Carrico, Sergey Menis, Gustavo H Kijak, Meera Bose, RV144 Sequencing Team, Miguel A Arroyo, Robert J O'Connell, Sorachai Nitayaphan, Punnee Pitisuttithum, Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Merlin L Robb, Tatsiana Kirys, Ivelin S Georgiev, Peter D Kwong, Konrad Scheffler, Sergei L Kosakovsky Pond, Jonathan M Carlson, Nelson L Michael, William R Schief, James I Mullins, Jerome H Kim, Peter B Gilbert

Get full text

Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics by Tom M. Quinn, Erin E. Gaughan, Annya Bruce, Jean Antonelli, Richard O'Connor, Feng Li, Sarah McNamara, Oliver Koch, Claire MacKintosh, David Dockrell, Timothy Walsh, Kevin G. Blyth, Colin Church, Jürgen Schwarze, Cecilia Boz, Asta Valanciute, Matthew Burgess, Philip Emanuel, Bethany Mills, Giulia Rinaldi, Gareth Hardisty, Ross Mills, Emily Gwyer Findlay, Sunny Jabbal, Andrew Duncan, Sinéad Plant, Adam D.L. Marshall, Irene Young, Kay Russell, Emma Scholefield, Alastair F. Nimmo, Islom B. Nazarov, Grant C. Churchill, James S.O. McCullagh, Kourosh H. Ebrahimi, Colin Ferrett, Kate Templeton, Steve Rannard, Andrew Owen, Anne Moore, Keith Finlayson, Manu Shankar-Hari, John Norrie, Richard A. Parker, Ahsan R. Akram, Daniel C. Anthony, James W. Dear, Nik Hirani, Kevin Dhaliwal

Get full text

A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection. by Scott P Lawrence, Samra E Elser, Workineh Torben, Robert V Blair, Bapi Pahar, Pyone P Aye, Faith Schiro, Dawn Szeltner, Lara A Doyle-Meyers, Beth S Haggarty, Andrea P O Jordan, Josephine Romano, George J Leslie, Xavier Alvarez, David H O'Connor, Roger W Wiseman, Christine M Fennessey, Yuan Li, Michael Piatak, Jeffrey D Lifson, Celia C LaBranche, Andrew A Lackner, Brandon F Keele, Nicholas J Maness, Mark Marsh, James A Hoxie

Get full text

Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings. by Matthew Dapas, Emma E Thompson, William Wentworth-Sheilds, Selene Clay, Cynthia M Visness, Agustin Calatroni, Joanne E Sordillo, Diane R Gold, Robert A Wood, Melanie Makhija, Gurjit K Khurana Hershey, Michael G Sherenian, Rebecca S Gruchalla, Michelle A Gill, Andrew H Liu, Haejin Kim, Meyer Kattan, Leonard B Bacharier, Deepa Rastogi, Matthew C Altman, William W Busse, Patrice M Becker, Dan Nicolae, George T O'Connor, James E Gern, Daniel J Jackson, Carole Ober

Get full text

A standard protocol to report discrete stage‐structured demographic information by Samuel J. L. Gascoigne, Simon Rolph, Daisy Sankey, Nagalakshmi Nidadavolu, Adrian S. Stell Pičman, Christina M. Hernández, Matthew E. R. Philpott, Aiyla Salam, Connor Bernard, Erola Fenollosa, Young Jun Lee, Jessica McLean, Shathuki Hetti Achchige Perera, Oliver G. Spacey, Maja Kajin, Anna C. Vinton, C. Ruth Archer, Jean H. Burns, Danielle L. Buss, Hal Caswell, Judy P. Che‐Castaldo, Dylan Z. Childs, Pol Capdevila, Aldo Compagnoni, Elizabeth Crone, Thomas H. G. Ezard, Dave Hodgson, Tiffany M. Knight, Owen R. Jones, Eelke Jongejans, Jenni McDonald, Brigitte Tenhumberg, Chelsea C. Thomas, Andrew J. Tyre, Satu Ramula, Iain Stott, Raymond L. Tremblay, Phil Wilson, James W. Vaupel, Roberto Salguero‐Gómez

Get full text

Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations by Tian Ge, Marguerite R. Irvin, Amit Patki, Vinodh Srinivasasainagendra, Yen-Feng Lin, Hemant K. Tiwari, Nicole D. Armstrong, Barbara Benoit, Chia-Yen Chen, Karmel W. Choi, James J. Cimino, Brittney H. Davis, Ozan Dikilitas, Bethany Etheridge, Yen-Chen Anne Feng, Vivian Gainer, Hailiang Huang, Gail P. Jarvik, Christopher Kachulis, Eimear E. Kenny, Atlas Khan, Krzysztof Kiryluk, Leah Kottyan, Iftikhar J. Kullo, Christoph Lange, Niall Lennon, Aaron Leong, Edyta Malolepsza, Ayme D. Miles, Shawn Murphy, Bahram Namjou, Renuka Narayan, Mark J. O’Connor, Jennifer A. Pacheco, Emma Perez, Laura J. Rasmussen-Torvik, Elisabeth A. Rosenthal, Daniel Schaid, Maria Stamou, Miriam S. Udler, Wei-Qi Wei, Scott T. Weiss, Maggie C. Y. Ng, Jordan W. Smoller, Matthew S. Lebo, James B. Meigs, Nita A. Limdi, Elizabeth W. Karlson

Get full text