Biomedical Promise of Sustainable Microwave-Engineered Symmetric Curcumin Derivatives by Cristina Doina Niţu, Maria Mernea, Raluca Ioana Vlasceanu, Bianca Voicu-Balasea, Madalina Andreea Badea, Florentina Monica Raduly, Valentin Rădiţoiu, Alina Rădiţoiu, Speranta Avram, Dan F. Mihailescu, Ionela C. Voinea, Miruna Silvia Stan

“…In this context, two symmetric curcumin derivatives (D1—(1E,6E)-1,7-bis(4-acetamidophenyl)hepta-1,6-diene-3,5-dione and D2—p,p-dihydroxy di-cinnamoyl methane) were obtained by the microwave-based method and evaluated for their antitumoral effect on human cervix cancer in comparison with toxicity on non-tumoral cells, taking into account that they were predicted to act as apoptosis agonists or anti-inflammatory agents. The HeLa cell line was incubated for 24 and 72 h with a concentration of 50 μg/mL of derivatives that killed almost half of the cells compared to the control. …”
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Reflecting on the role of human‐felid conflict and local use in big cat trade by Melissa Arias, Peter Coals, Ardiantiono, Joshua Elves‐Powell, Jessica Bell Rizzolo, Arash Ghoddousi, Valeria Boron, Mariana daSilva, Vincent Naude, Vivienne Williams, Shashank Poudel, Andrew Loveridge, Esteban Payán, Kulbhushansingh Suryawanshi, Amy Dickman

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Engineering the Surface of Ti₃C₂ MXene Nanosheets for High Stability and Multimodal Anticancer Therapy by Chiranjeevi Korupalli, Kai-Long You, Girum Getachew, Akash S. Rasal, Worku Batu Dirersa, Mochamad Zakki Fahmi, Jia-Yaw Chang

“…During in vitro studies, the CGDSTC NSs exhibited cytocompatability to HePG2 and HeLa cells under nonstimulus conditions. However, they elicited more than 90% cell-killing efficiency in the presence of glucose and laser irradiation via the cooperative effect between starvation therapy and phototherapy. …”
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Variants of Streptococcus pneumoniae Serotype 14 from Papua New Guinea with the Potential to Be Mistyped and Escape Vaccine-Induced Protection by Sam Manna, Leena Spry, Ashleigh Wee-Hee, Belinda D. Ortika, Laura K. Boelsen, Steven Batinovic, Nadia Mazarakis, Rebecca L. Ford, Stephanie W. Lo, Stephen D. Bentley, Fiona M. Russell, Christopher C. Blyth, William S. Pomat, Steve Petrovski, Jason Hinds, Paul V. Licciardi, Catherine Satzke

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Theoretical evaluation of the impact of diverse treatment conditions by calculation of the tumor control probability (TCP) of simulated cervical cancer Hyperthermia-Radiotherapy (H... by Sergio Mingo Barba, Adela Ademaj, Dietmar Marder, Oliver Riesterer, Marco Lattuada, Rudolf M. Füchslin, Alke Petri-Fink, Stephan Scheidegger

“…AbstractIntroduction Hyperthermia (HT) induces various cellular biological processes, such as repair impairment and direct HT cell killing. In this context, in-silico biophysical models that translate deviations in the treatment conditions into clinical outcome variations may be used to study the extent of such processes and their influence on combined hyperthermia plus radiotherapy (HT + RT) treatments under varying conditions.Methods An extended linear-quadratic model calibrated for SiHa and HeLa cell lines (cervical cancer) was used to theoretically study the impact of varying HT treatment conditions on radiosensitization and direct HT cell killing effect. …”
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Biological and Photocatalytic Activity of Silver Nanoparticle Synthesized from Ehretia laevis Roxb. Leaves Extract by Sudipata Panja, Indranil Choudhuri, Kalyani Khanra, Bikas Ranjan Pati, Nandan Bhattacharyya

“…At a concentration of 25 μg/mL, it killed 70 ± 10.24% of Culex quinquefasciatus larvae after 72 h treatment. …”
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The effects of tumor necrosis factor (TNF) derivatives on TNF receptors. by Tchorzewski, H, Zeman, K, Paleolog, E, Brennan, F, Feldmann, M, Kahan, M, Guga, P, Kwinkowski, M, Szymanska, B, Jarosz, J

“…We observed binding to the p75 TNF receptor on Jijoye Burkitt lymphoma cells with native TNF-alpha and mutein III alone, whereas the p55 TNF receptor on the human epithelioid carcinoma cell line HeLa bound TNF-alpha, mutein III and mutein V. Muteins IV and VI failed to recognize either TNF receptor. …”

Potential Mammalian Vector-Borne Diseases in Live and Wet Markets in Indonesia and Myanmar by Vincent Nijman, K. A. I. Nekaris, Chris R. Shepherd, Lucy Vigne, Ahmad Ardiansyah, Muhammad Ali Imron, Qinyong Ni, Katherine Hedger, Marco Campera, Thais Q. Morcatty

“…We assessed the potential for spreading vector-borne diseases in two live and wet markets in Myanmar (Mong La, on the Myanmar-China border) and Indonesia (Sukahaji in Bandung on the island of Java) by making an inventory of all live and freshly killed wild mammals for sale. …”
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Effects of <i>Escherichia coli</i> LPS Structure on Antibacterial and Anti-Endotoxin Activities of Host Defense Peptides by Ali Javed, Melanie D. Balhuizen, Arianne Pannekoek, Floris J. Bikker, Dani A. C. Heesterbeek, Henk P. Haagsman, Femke Broere, Markus Weingarth, Edwin J. A. Veldhuizen

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Lack of Functional Trehalase Activity in <i>Candida parapsilosis</i> Increases Susceptibility to Itraconazole by Ruth Sánchez-Fresneda, María Luz Muñoz-Megías, Genoveva Yagüe, Francisco Solano, Sergi Maicas, Juan Carlos Argüelles

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Plasmonic Gold Nanoisland Film for Bacterial Theranostics by Shih-Hua Tan, Sibidou Yougbaré, Hsuan-Ya Tao, Che-Chang Chang, Tsung-Rong Kuo

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Roles of intestinal intraepithelial lymphocytes in specific-pathogen-free chickens infected with lentogenic and velogenic newcastle disease virus strains by Hamisu, Tasiu Mallam

“…The main objective of this study is to investigate the role of these cells in specific-pathogen-free (SPF) chickens following inoculation with NDV lentogenic strain LaSota, and/or velogenic strains, genotypes VII and VIII. …”
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Lethality of Honey Bee Stings to Heavily Armored Hornets by Gaoying Gu, Yichuan Meng, Ken Tan, Shihao Dong, James C. Nieh

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Reduction-sensitive fluorescence enhanced polymeric prodrug nanoparticles for combinational photothermal-chemotherapy by Zhang, Yuanyuan, Yang, Dan, Chen, Hongzhong, Lim, Wei Qi, Phua, Fiona Soo Zeng, An, Guanghui, Yang, Piaoping, Zhao, Yanli

“…In vitro cell viability assays confirmed that the cancer cells were efficiently killed by the treatment of the nanoplatform under NIR light irradiation. …”
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Synchrotron-Based Fourier-Transform Infrared Micro-Spectroscopy (SR-FTIRM) Fingerprint of the Small Anionic Molecule Cobaltabis(dicarbollide) Uptake in Glioma Stem Cells by Miquel Nuez-Martínez, Leire Pedrosa, Immaculada Martinez-Rovira, Ibraheem Yousef, Diouldé Diao, Francesc Teixidor, Elisabetta Stanzani, Fina Martínez-Soler, Avelina Tortosa, Àngels Sierra, José Juan Gonzalez, Clara Viñas

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Rational design of drug-like compounds targeting Mycobacterium marinum MelF protein. by Renu Dharra, Sakshi Talwar, Yogesh Singh, Rani Gupta, Jeffrey D Cirillo, Amit K Pandey, Mahesh Kulharia, Promod K Mehta

“…Such inhibitors targeting the anti-ROS/RNS machinery may facilitate the efficient killing of replicating and nonreplicating mycobacteria inside the host cells.…”
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Negative human–crocodile interactions in Kariba, Zimbabwe: data to support potential mitigation strategies by Joshua Matanzima, Ivan Marowa, Tamuka Nhiwatiwa

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Ocean warming pattern effects on future changes in East Asian atmospheric rivers by Youichi Kamae, Wei Mei, Shang-Ping Xie

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The commutative nonassociative algebra of metric curvature tensors by Daniel J. F. Fox

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Human intraspecific somatic cell hybrids: a genetic and karyotypic analysis of crosses between lymphocytes and D98/AH-2. by Bengtsson, B, Nabholz, M, Kennett, R, Bodmer, W, Povey, S, Swallow, D

“…The HL-A antigens of the lymphocyte donor as well as the W28 specificity from HeLa were easily recognized by a cytotoxicity assay on the hybrid cells, while D98/AH-2 itself was not killed in the normal way by any HL-4 typing sera. …”