Association between endometriosis and the interleukin 1A (IL1A) locus. by Sapkota, Y, Low, S, Attia, J, Gordon, S, Henders, A, Holliday, E, MacGregor, S, Martin, N, McEvoy, M, Morris, A, Takahashi, A, Scott, R, Kubo, M, Zondervan, K, Montgomery, G, Nyholt, DR

“…STUDY QUESTION: Are single-nucleotide polymorphisms (SNPs) at the interleukin 1A (IL1A) gene locus associated with endometriosis risk? SUMMARY ANSWER: We found evidence for strong association between IL1A SNPs and endometriosis risk. …”

Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes. by Tousoulis, D, Briasoulis, A, Papageorgiou, N, Antoniades, C, Stefanadis, C

Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent by Pattenden, SG, Klose, R, Karaskov, E, Bremner, R

“…Chroma tin immunoprecipitation revealed that BRG1 interacts directly with the endogenous CIITA promoter in an IFN‐γ‐inducible fashion, while in vivo DNase I footprinting and restriction enzyme accessibility assays showed that chromatin remodeling at this locus requires functional BRG1. These data provide the first link between a cytokine pathway and SWI/SNF, and suggest a novel role for this chromatin‐remodeling complex in immune surveillance.…”

Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q. by Consortium, I

“…To further characterize this susceptibility locus, linkage analysis has now been completed on 170 multiplex IMGSAC families. …”

Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia by Mathieson, I, Munafò, MR, Flint, J

“…We find no evidence that common variants at the DISC1 locus are associated with schizophrenia. © 2012 Macmillan Publishers Limited All rights reserved.…”

Fine-mapping of the 1p11.2 breast cancer susceptibility locus by Horne, H, Chung, C, Zhang, H, Yu, K, Prokunina-Olsson, L, Michailidou, K, Bolla, M, Wang, Q, Dennis, J, Hopper, J, Southey, M, Schmidt, M, Broeks, A, Muir, K, Lophatananon, A, Fasching, P, Beckmann, M, Fletcher, O, Johnson, N, Sawyer, E, Tomlinson, I, Burwinkel, B, Marme, F, Guénel, P, Truong, T, Bojesen, S, Flyger, H, Benitez, J, González-Neira, A, Anton-Culver, H, Neuhausen, S, Brenner, H, Arndt, V, Meindl, A, Schmutzler, R, Brauch, H, Hamann, U, Nevanlinna, H, Khan, S, Matsuo, K, Iwata, H, Dörk, T, Bogdanova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kosma, V, Chenevix-Trench, G, Wu, A, Ven den Berg, D, Smeets, A, Zhao, H, Chang-Claude, J, Rudolph, A, Radice, P, Barile, M, Couch, F, Vachon, C, Giles, G, Milne, R, Haiman, C, Marchand, L, Goldberg, M, Teo, S, Taib, N, Kristensen, V, Borresen-Dale, A, Zheng, W, Shrubsole, M, Winqvist, R, Jukkola-Vuorinen, A, Andrulis, I, Knight, J, Devilee, P, Seynaeve, C, García-Closas, M, Czene, K, Darabi, H, Hollestelle, A, Martens, J, Li, J, Lu, W, Shu, X, Cox, A, Cross, S, Blot, W, Cai, Q, Shah, M, Luccarini, C, Baynes, C, Harrington, P, Kang, D, Choi, J, Hartman, M, Chia, K, Kabisch, M, Torres, D, Jakubowska, A, Lubinski, J, Sangrajrang, S, Brennan, P, Slager, S, Yannoukakos, D, Shen, C, Hou, M, Swerdlow, A, Orr, N, Simard, J, Hall, P, Pharoah, P, Easton, D, Chanock, S, Dunning, A, Figueroa, J

“…Fine-mapping analysis of the 1p11.2 breast cancer susceptibility locus confirms this region to be limited to risk to cancers that are ER-positive.…”

Characterisation of a major locus for developmental dyslexia on 18p11.2. by MacPhie, I, Fisher, S, Francks, C, Marlow, A, Cardon, L, Talcott, J, Richardson, A, Stein, J, Monaco, A

DNA polymorphism, haplotype structure and balancing selection in the Leavenworthia PgiC locus. by Filatov, D, Charlesworth, D

“…Although recombination is estimated to be high in this locus, extensive haplotype structure was observed for the entire 2.3-kb region. …”

Unilateral incompatibility within the brassicaceae: further evidence for the involvement of the self-incompatibility (S)-locus. by Hiscock, S, Dickinson, H

“…The results presented show that the presence of an incompatibility system is important in predicting the outcome of interspecific and intergeneric crosses and, combined with the physiological similarities between UI and SI, would suggest an involvement of the S-locus in UI. …”

Cross-modal selective attention: on the difficulty of ignoring sounds at the locus of visual attention. by Spence, C, Ranson, J, Driver, J

Triplet repeat expansion at the FRAXE locus and X-linked mild mental handicap. by Knight, S, Voelckel, M, Hirst, M, Flannery, A, Moncla, A, Davies, K

“…Here we present data on families that previously had been diagnosed as having the fragile X syndrome but that later were found to be negative for trinucleotide repeat expansion at the FRAXA locus. In these families we demonstrate the presence of a GCC trinucleotide repeat expansion at the FRAXE locus. …”

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates. by Salter, S, Hinds, J, Gould, K, Lambertsen, L, Hanage, W, Antonio, M, Turner, P, Hermans, P, Bootsma, H, O'Brien, K, Bentley, S

“…The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. …”

The thyroglobulin gene: The third locus for autoimmune thyroid disease or a false dawn? by Gough, S

“…Despite numerous studies, the identification of a third locus has remained elusive. Genetic-linkage studies have implicated chromosome 8q24 as a susceptibility locus for AITD. …”

DIMENSIONALITY OF ROTTER LOCUS OF CONTROL SCALE - AN APPLICATION OF THE VERY SIMPLE STRUCTURE TECHNIQUE by Parkes, K

Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia. by Mathieson, I, Munafò, MR, Flint, J

“…We find no evidence that common variants at the DISC1 locus are associated with schizophrenia.…”

A recognisable 6p deletion syndrome and a locus for Perthes' disease? by Islam, L, Waters, K, Ragoussis, J, MacDermot, K

Linking genotypes database with locus-specific database and genotype-phenotype correlation in phenylketonuria. by Wettstein, S, Underhaug, J, Perez, B, Marsden, B, Yue, W, Martinez, A, Blau, N

“…A total of 834 phenylalanine hydroxylase gene variants from the locus-specific database PAHvdb and genotypes of 4181 phenylketonuria patients from the BIOPKU database were characterized using FoldX, SIFT Blink, Polyphen-2 and SNPs3D algorithms. …”

Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes. by Brüggemann, M, Free, J, Diamond, A, Howard, J, Cobbold, S, Waldmann, H

“…Analysis of genomic DNA by Southern blotting permitted identification of the C gamma 2c gene and led to the proposal of the following gene order for the rat Ig heavy chain locus: D-JH-C mu-C delta-(C gamma 2c, C gamma 2a)-C gamma 1-C gamma 2b-C epsilon-C alpha. …”

PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders. by James, E, Harney, S, Wordsworth, B, Cookson, W, Davis, S, Moffatt, M

Transcriptional derepression of the ERVWE1 locus following influenza A virus infection. by Li, F, Nellåker, C, Sabunciyan, S, Yolken, R, Jones-Brando, L, Johansson, A, Owe-Larsson, B, Karlsson, H

“…UNLABELLED: Syncytin-1, a fusogenic protein encoded by a human endogenous retrovirus of the W family (HERV-W) element (ERVWE1), is expressed in the syncytiotrophoblast layer of the placenta. This locus is transcriptionally repressed in adult tissues through promoter CpG methylation and suppressive histone modifications. …”