Evidence that a locus for familial psoriasis maps to chromosome 4q. by Matthews, D, Fry, L, Powles, A, Weber, J, McCarthy, M, Fisher, E, Davies, K, Williamson, R

“…Parametric linkage analysis indicated that a susceptibility locus for familial psoriasis was located on chromosome 4q. …”

Functional evaluation of the human fat distribution HOXC13 gene locus by Kuo, F

“…Detailed annotation of HOTAIR-haplotype tagging single nucleotide polymorphisms (SNPs) identified the minor allele of rs76084431 as a GSAT HOTAIR expression quantitative trait locus (eQTL) associated with increased android to gynoid fat mass ratio in females. …”

A major quantitative trait locus influences hyperactivity in the WKHA rat. by Moisan, M, Courvoisier, H, Bihoreau, M, Gauguier, D, Hendley, E, Lathrop, M, James, MR, Mormède, P

R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus. by Sun, Q, Csorba, T, Skourti-Stathaki, K, Proudfoot, N, Dean, C

“…We have identified a homeodomain protein, AtNDX, that regulates COOLAIR, a set of antisense transcripts originating from the 3' end of Arabidopsis FLOWERING LOCUS C (FLC). AtNDX associates with single-stranded DNA rather than double-stranded DNA non-sequence-specifically in vitro, and localizes to a heterochromatic region in the COOLAIR promoter in vivo. …”

EXTENSIONS OF THE FRAME ALIGNMENT TECHNIQUE AND THEIR USE IN THE CHARACTERISTIC LOCUS DESIGN METHOD by Edmunds, J, Kouvaritakis, B

“…Frame alignment, performed by the ALIGN algorithm, plays an important role in the characteristic locus design method. A number of extensions to ALIGN intended to enhance the effectiveness of the design technique are proposed. …”

Association of the TSHR gene with Graves' disease: the first disease specific locus. by Dechairo, B, Zabaneh, D, Collins, J, Brand, O, Dawson, G, Green, A, Mackay, I, Franklyn, J, Connell, J, Wass, J, Wiersinga, WM, Hegedus, L, Brix, T, Robinson, BG, Hunt, P, Weetman, A, Carey, A, Gough, S

“…These results in two independent Caucasian data sets suggest that the TSHR is the first replicated GD-specific locus meriting further fine mapping and functional analysis to identify the aetiological variants.…”

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. by Hamilton, G, Killick, R, Genetic, A, Translational, G, Lambert, J, Amouyel, P, European, A, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R

“…Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. …”

Isolation and characterisation of the B42 mating type locus of Coprinus cinereus by Halsall, J, Halsall, John

“…The B mating type locus of the basidiomycete <em>Coprinus cinereus</em> contains a multiallelic gene complex encoding peptide pheromones and transmembrane receptors. …”

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus by Hamilton, G, Killick, R, Lambert, J, Amouyel, P, Carrasquillo, M, Pankratz, V, Graff-Radford, N, Dickson, D, Petersen, R, Younkin, S, Powell, J, Wade-Martins, R

“…Here, we have developed a novel functional genomics methodology to express common locus haplotypes to assess functional differences. …”

Evaluating the results of genomewide linkage scans of complex traits by locus counting. by Wiltshire, S, Cardon, L, McCarthy, M

“…We have explored the characteristics of such a locus-counting method over a range of experimental conditions typically encountered during genomewide scans for complex trait loci. …”

MULTIVARIABLE CONTROL-SYSTEM FOR 2-BED REACTORS BY THE CHARACTERISTIC LOCUS METHOD by Foss, A, Edmunds, J, Kouvaritakis, B

Characterization of a major modifier locus for polycystic kidney disease (Modpkdr1) in the Han:SPRD(cy/+) rat in a region conserved with a mouse modifier locus for Alport syndrome. by Bihoreau, M, Megel, N, Brown, J, Kränzlin, B, Crombez, L, Tychinskaya, Y, Broxholme, J, Kratz, S, Bergmann, V, Hoffman, S, Gauguier, D, Gretz, N

“…The genetic dissection of PKD in the cross allowed us to detect a modifier locus, Modpkdr1, on rat chromosome 8 that controls PKD severity, kidney mass and plasma urea concentration. …”

LOCUS, a variable-geometry sailboat : construction, and initial experiments on steering qualities / by 455863 Letcher, John S.

Locus Coeruleus Norepinephrine in Learned Behavior: Anatomical Modularity and Spatiotemporal Integration in Targets by Breton-Provencher, Vincent, Drummond, Gabrielle T, Sur, Mriganka

“…<jats:p>The locus coeruleus (LC), a small brainstem nucleus, is the primary source of the neuromodulator norepinephrine (NE) in the brain. …”
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Locus Coeruleus Norepinephrine in Learned Behavior: Anatomical Modularity and Spatiotemporal Integration in Targets by Breton-Provencher, Vincent, Drummond, Gabrielle, Sur, Mriganka

“…<jats:p>The locus coeruleus (LC), a small brainstem nucleus, is the primary source of the neuromodulator norepinephrine (NE) in the brain. …”
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Explorations of the impact of "sticky" local information on the locus of innovation : a progress review

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Factors influencing the locus of innovation activity leading to scientific instrument and plastics innovations by Berger, Alan Jacob

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Unified Modeling of Gene Duplication, Loss, and Coalescence Using a Locus Tree by Rasmussen, Matthew D., Kellis, Manolis

“…Interestingly, this model implies that in addition to the usual gene tree and species tree, there exists a third tree, the locus tree, which will likely have many applications. …”
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Polyphyly of non-bioluminescent Vibrio fischeri sharing a lux-locus deletion by Wollenberg, M. S., Preheim, Sarah Pachocha, Polz, Martin F., Ruby, E. G., Preheim, Sarah Pacocha

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Management's responsibility acceptance, locus of breach, and investors' reactions to internal control reports by Tan, Hun-Tong, Yu, Yao

“…Applying this theory, we conduct experiments to examine how the locus of breach (external versus internal) moderates the efficacy of management's responsibility acceptance (higher versus lower). …”
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