Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome by Pedro David Wendel-Garcia, Rolf Erlebach, Daniel Andrea Hofmaenner, Giovanni Camen, Reto Andreas Schuepbach, Christoph Jüngst, Beat Müllhaupt, Jan Bartussek, Philipp Karl Buehler, Rea Andermatt, Sascha David

“…Patients having received ketamine infusion had a multivariable adjusted competing risk hazard of developing a cholestatic liver injury during their ICU stay of 3.2 [95% confidence interval, 1.3–7.8] (p = 0.01). Conclusions A causally plausible, dose–effect relationship between long-term infusion of ketamine and rising total bilirubin levels, as well as an augmented, ketamine-associated, hazard of cholestatic liver injury in critically ill COVID-19 patients could be shown. …”
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Personality traits and mental distress after COVID-19 testing. Prospective long-term analysis in a Viennese cohort by Claudia Guttmann-Ducke, Sonja Klinger, Sonja Klinger, Rolf Ziesche, Bernd Otzelberger, Marco Idzko, Armin Ponocny, Simon Gabriel Prantl, Elisabeth Ponocny-Seliger

“…Following 90 days (visit 3), development of mental distress was addressed by a combination of DASS and PTSD, while the possible long-term manifestation of PTSD was evaluated 9 months later (visit 4).ResultsAt visit 1, 7.4 percent of the total sample (n = 867) demonstrated a positive screening for PTSD, while after nine months (at visit 4), 8.9 percent of the remaining sample (n = 204) had positive screening results. …”
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Understanding the Experience of Long COVID Symptoms in Hospitalized and Non-Hospitalized Individuals: A Random, Cross-Sectional Survey Study by Jacqueline A. Krysa, Mikayla Buell, Kiran Pohar Manhas, Katharina Kovacs Burns, Maria J. Santana, Sidney Horlick, Kristine Russell, Elizabeth Papathanassoglou, Chester Ho

“…Significantly more previously hospitalized respondents self-reported long COVID symptoms (81 (49.1%)) compared to non-hospitalized respondents (42 (25.5%), <i>p</i> < 0.0001). …”
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Determination of Lidar Ratio for Major Aerosol Types over Western North Pacific Based on Long-Term MPLNET Data by Sheng-Hsiang Wang, Heng-Wai Lei, Shantanu Kumar Pani, Hsiang-Yu Huang, Neng-Huei Lin, Ellsworth J. Welton, Shuenn-Chin Chang, Yueh-Chen Wang

“…Fall season (October–November) was the prevailing season for the Type 1, whereas type 2 mainly happened in spring (March–April). …”
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Changes in the Incidence Rates of Gastrointestinal Diseases Due to the COVID-19 Pandemic in South Korea: A Long-Term Perspective by Hyo Geun Choi, Ho Suk Kang, Hyun Lim, Joo-Hee Kim, Ji Hee Kim, Seong-Jin Cho, Eun Sook Nam, Kyueng-Whan Min, Ha Young Park, Nan Young Kim, Mi Jung Kwon

“…Changes in the monthly incidence rates (January 2018 to June 2021) of common gastrointestinal diseases were assessed using data from the Korean National Health Insurance Service by comparing the data of two periods: before COVID-19 (January 2018–February 2020) and during COVID-19 (March 2020–June 2021). The Mann–Whitney <i>U</i> test and Levene’s test were used to compare the differences in the incidences before and during the pandemic. …”
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What contributes to the long-term implementation of an evidence-based early childhood intervention: a qualitative study from Germany by Marie Lisanne Schepan, Marie Lisanne Schepan, Tanja Jungmann, Sören Kliem, Carolin Siegert, Malte Sandner, Tilman Brand

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Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil by Jacqueline Ferreira de Oliveira, Renata Eliane de Ávila, Neimy Ramos de Oliveira, Natália da Cunha Severino Sampaio, Maiara Botelho, Fabíola Araújo Gonçalves, Cirilo José Ferreira Neto, Ana Carolina de Almeida Milagres, Tatiane Cristina Caldeira Gomes, Tássia Lopardi Pereira, Renan Pedra de Souza, Israel Molina

“…Methods: Surviving patients discharged from the hospital between July 1, 2020 and March 31, 2021 were assessed between 2 and 12 months after acute onset of COVID-19. …”
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Long-term prognostic value of inflammatory biomarkers for patients with acute heart failure: Construction of an inflammatory prognostic scoring system by Xu Zhu, Iokfai Cheang, Fang Xu, Rongrong Gao, Shengen Liao, Wenming Yao, Yanli Zhou, Haifeng Zhang, Haifeng Zhang, Xinli Li

“…This study was to assess the long-term prognostic value of combining the accessible inflammatory markers in relation to all-cause mortality in patients with AHF.MethodsConsecutive patients with AHF who were hospitalized between March 2012 and April 2016 at the Department of Cardiology of the First Affiliated Hospital of Nanjing Medical University were enrolled in this prospective study. …”
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Long-term cognitive performance and its relation to anti-inflammatory therapy in a cohort of survivors of severe COVID-19 by Harmke B. Duindam, Roy P.C. Kessels, Bram van den Borst, Peter Pickkers, Wilson F. Abdo

“…Results: 96 patients were included (March 2020–June 2021, median [IQR] age 61 [55–69] years). 91% received invasive mechanical ventilation, and mean ± SD severity-of-disease APACHE–II–score at admission was 15.8 ± 4.1. …”
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A Novel Approach to Assessing Light Extinction with Decade-Long Observations of Chemical and Optical Properties in Seoul, South Korea by Seung-Myung Park, Jong Sung Park, In-Ho Song, Jeonghwan Kim, Hyun Woong Kim, Jaeyun Lee, Jung Min Park, Jeong-ho Kim, Yongjoo Choi, Hye Jung Shin, Joon Young Ahn, Yu Woon Jang, Taehyoung Lee, Gangwoong Lee

“…We performed continuous long-term measurements of PM_2.5 mass, comprehensive chemical composition, and optical properties, including scattering and absorption coefficients, from March 2011 to December 2020 at the Metropolitan Air Quality Research Center in Seoul, South Korea. …”
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Impact of Long-Term Home Quarantine on Mental Health and Physical Activity of People in Shanghai During the COVID-19 Pandemic by Wentong Zhu, Doudou Xu, Hui Li, Gang Xu, Jingyan Tian, Jingyan Tian, Luheng Lyu, Naifu Wan, Lijiang Wei, Wuwei Rong, Chenchen Liu, Beiwen Wu, Xiaolan Bian, Ankang Lyu

“…This study aimed to investigate the effects of long-term home quarantine on the mental health of people during the COVID-19 epidemic in Shanghai. …”
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Effect of long working hours on work-related musculoskeletal disorders among operation and maintenance workers of power supply enterprises by Baoyu ZHU, Dan ZHANG, Zhanhui LIANG, Yang GAO, Hongyan LI, Jiajie LI, Qingsong CHEN

“…The results of multiple logistic regression showed that after adjusting education, smoking, exercise, awkward postures, often handling heavy objects, limited space to operate, long-time heavy trunk bending, long-time neck tilting backward, and keeping arms above shoulders, compared with working ≤40 h per week, the risk of WMSDs among workers working >49 h per week was higher (OR=1.406, 95%CI: 1.011-1.955). …”
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Characterisation, symptom pattern and symptom clusters from a retrospective cohort of Long COVID patients in primary care in Catalonia by Gemma Torrell, Diana Puente, Constanza Jacques-Aviñó, Lucia A. Carrasco-Ribelles, Concepció Violán, Tomás López-Jiménez, Veronica Royano, Alba Molina Cantón, Laura Medina-Perucha, Israel Rodríguez-Giralt, Anna Berenguera

“…Recruitment was from March 2020 to June 2021. Exclusion criteria were being admitted to an ICU, < 18 years of age and not living in Catalonia. …”
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Short- and Long-Term Efficacy and Safety of Deep-Brain Stimulation in Parkinson’s Disease Patients aged 75 Years and Older by Chao Jiang, Jian Wang, Tong Chen, Xuemei Li, Zhiqiang Cui

“…Sleep, cognition, and mood were slightly improved at 1 year post operation (<i>p</i> < 0.05), and LEDD was reduced from 650 mg (baseline) to 280 mg and 325 mg at 1 year post operation and the final follow-up, respectively (<i>p</i> < 0.05). …”
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A long-term time series of global and diffuse photosynthetically active radiation in the Mediterranean: interannual variability and cloud effects by P. Trisolino, P. Trisolino, A. di Sarra, F. Anello, C. Bommarito, T. Di Iorio, D. Meloni, F. Monteleone, G. Pace, S. Piacentino, D. Sferlazzo

“…The annual average CRE is about −14.7 W m⁻² for the global PAR and +8.1 W m⁻² for the diffuse PAR. The smallest CRE is observed in July, due to the high cloud-free condition frequency. …”
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Efficacy of COVID-19 control measures on post-vaccination outbreak in Italian Long Term Care Facilities: implications for policies by Alba Malara, Marianna Noale, Caterina Trevisan, Caterina Trevisan, Angela Marie Abbatecola, Gilda Borselli, Carmine Cafariello, Pietro Gareri, Stefano Fumagalli, Enrico Mossello, Stefano Volpato, Fabio Monzani, Alessandra Coin, Chukwuma Okoye, Giuseppe Bellelli, Stefania Del Signore, Gianluca Zia, Raffaele Antonelli Incalzi, Annapina Palmieri, Giorgio Fedele, Graziano Onder, Graziano Onder, The GeroCovid Vax Working Group

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Risk factors for long-term invasive mechanical ventilation: a longitudinal study using German health claims data by Franziska C. Trudzinski, Julia D. Michels-Zetsche, Benjamin Neetz, Jan Meis, Michael Müller, Axel Kempa, Claus Neurohr, Armin Schneider, Felix J. F. Herth, Joachim Szecsenyi, Elena Biehler, Thomas Fleischauer, Michel Wensing, Simone Britsch, Janina Schubert-Haack, Thomas Grobe, Timm Frerk, The PRiVENT-study group

“…Results In the analysis of 7758 hospitalisations, criteria for long-term IMV were met in 38.3% of cases, of which 13.9% had evidence of HMV, 73.1% received IMV ≥ 500 h and/or 40.3% were re-hospitalised with IMV. …”
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Food Preference of Bullet Tuna (<i>Auxis rochei</i> Risso, 1810) in Prigi Coast of Trenggalek Regency, East Java by Bella Pradita Agustina, Ana Ariasari, Tony Budi Satriyo, Eko Setyobudi

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Sars-Cov-2 Infection in Patients on Long-Term Treatment with Macrolides in Spain: A National Cross-Sectional Study by Carmen Marina Meseguer Barros, Natalia Alzueta Isturiz, Rita Sainz de Rozas Aparicio, Rafael Aguilella Vizcaíno, Laura López Esteban, Sonia Anaya Ordóñez, Itxasne Lekue Alkorta, Salvadora Martín Suances, Jorge Ignacio Jiménez Arce, Maite Fernández Vicente, Yolanda Borrego Izquierdo, Raquel Prieto Sánchez, Silvia Casado Casuso, Rosa Madridejos, Carmen Marquina Verde, Rosa Tomás Sanz, María Oro Fernández, Sara Gallardo Borge, Eva Lázaro López, María Belén Pina Gadea, Mercedes Pereira Pía, María Victoria Maestre-Sánchez, Esther Ribes-Murillo, Constanza Gómez de Oña, Álvarez María Jesús Lallana, Concepción Celaya Lecea, María Ana Prado Prieto, Aranzazu Aranguez Ruiz, Vicente Olmo Quintana, Noemí Villén Romero, Carolina Payá Giner, Angeles Lloret Callejo, Alvaro Fernández Ferreiro, Blanca Basagoiti Carreño, Ana Aurelia Iglesias Iglesias, Antonio Martín Alonso, Ana Díez Alcántara, Esther Marco Tejón, Marta Lestón Vázquez, Mª Ángeles Ariza Copado, Marta Aparicio Cueva, Belén Escudero Vilaplana, Marisa Nicieza, Gracia Picazo Sanchiz, Genma María Silva Riádigos, Lucía Jamart Sánchez, Ángel García Álvarez, Antonio García Bonilla, Rafael Herrero Delicado, Virginia Arroyo Pineda, Belén de la Hija, Amelia Troncoso Mariño, Isabel Tofiño González, Mónica Susana Mateu García, Pablo García Vázquez, Joaquín Pérez Martín, Rocío Fernández-Urrusuno

“…Patients with macrolides dispensed continuously from 1 October 2019 to 31 March 2020, were considered. …”
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Prevention and treatment of catheter-related venous thrombosis in long-term parenteral nutrition: A SINuC position statement by Vincenzo Zaccone, Luca Santoro, Emanuele Guerrieri, Ilaria Diblasi, Ilaria Roncarati, Giovanna Viticchi, Pietro Vecchiarelli, Angelo Santoliquido, Angelo Santoliquido, Francesca Fiore, Alessio Molfino, Francesco Landi, Francesco Landi, Gianluca Moroncini, Antonio Gasbarrini, Antonio Gasbarrini, Maurizio Muscaritoli, Lorenzo Falsetti

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