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    The Accuracy and Reliability of Sleep Staging and Sleep Biomarkers in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder by Levendowski DJ, Neylan TC, Lee-Iannotti JK, Timm PC, Guevarra C, Angel E, Shprecher D, Mazeika G, Walsh CM, Boeve BF, St Louis EK

    Published 2023-05-01
    “…Daniel J Levendowski,1 Thomas C Neylan,2 Joyce K Lee-Iannotti,3 Paul C Timm,4 Cyrus Guevarra,3 Elise Angel,1 David Shprecher,5 Gandis Mazeika,1 Christine M Walsh,6 Bradley F Boeve,4 Erik K St Louis4 1Sleep and Respiratory Research, Advanced Brain Monitoring, Inc, Carlsbad, CA, USA; 2Weill Institute for Neurosciences, University of California, San Francisco, CA, USA; 3Department of Neurology and Medicine, Banner University Medical Center, Phoenix, AZ, USA; 4Mayo Center for Sleep Medicine, Departments of Neurology and Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA; 5Banner Sun Health Research Institute, Sun City, AZ, USA; 6Memory and Aging Center, University of California, San Francisco, CA, USACorrespondence: Daniel J Levendowski, Advanced Brain Monitoring, Inc, 2237 Faraday Avenue, Carlsbad, CA, 92008, USA, Tel +1 760 521 1545, Fax +1 760 476 3620, Email Dan@b-alert.comPurpose: This study aimed to establish the diagnostic accuracy of a previously validated sleep staging system in patients with probable isolated REM sleep behavior disorder (iRBD), and to compare physicians’ diagnoses of iRBD based on REM sleep without atonia (RSWA) to non-REM hypertonia (NRH), a sleep measure independently associated with Parkinsonian spectrum disorders.Patients and Methods: Twenty-six patients with a history of dream enactment behavior underwent a diagnostic PSG with simultaneous Sleep Profiler (SP) acquisition at two sites. …”
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