Homology modeling of human sweet taste receptors: T1R2-T1R3 by Yousif, Ragheed Hussam, Ahmad Khairudin, Nurul Bahiyah

Molecular Docking and Molecular Dynamics Simulation using Monascus sp. as a Candidate Cervical Cancer Drug by Anna Yuliana, Ira Rahmiyani, Cindi Kartika

“…The results of docked with AutodockTools were visualized with Pymol, analyzed the effectiveness using the Ramachandran plot. The docking results show that there are 2 pigments that have lower G than raloxifen in estrogen receptor beta with the lowest G indicated by the pigment Monascin and Ankaflavin, which is -6.94 kcal/mol with Ki value of 39.49 nM and -6.22 kcal/mol with Ki value of 27.78 nM. …”
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TSHR169 Antigen Specifically Binds to the Thyroid-stimulating Autoantibody, Representing an Effective Biomarker for Graves’ Disease by Zulkarnain Zulkarnain, Hidayat Sujuti, Djoko Wahono Soeatmadji, Didik Huswo Utomo, Aulanni’am Aulanni’am

“…The model was validated by generating a Ramachandran plot with the RAMPAGE server. Prediction of the molecular interaction between TSHR and M22 was performed using the HADDOCK web server (version 2.2). …”
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Proceedings of the International Conference on Advanced Manufacturing Technology, August 29 - 30 1994, Johor Bahru, Malaysia / by The International Conference on Advanced Manufacturing Technology (1994 : Johor Bahru), Venkatesh, V. C. (Vellore Chelvaraj), Universiti Teknologi Malaysia. Fakulti Kejuruteraan Jentera

“…Uematsu, K.Kitajima, C.S.Sharma and P.J.Chung -- Thermal stress induced wear of grinding wheels / K.I.Ramachandran, L.Vijayaraghavan and R.Krishnamurthy -- Some fundamental and practical aspects of twist drills and drilling / E.J.A.Armarego -- Hot machining process for improved metal removal rates in turning operations / G.Madhavulu and B.Ahmed --Optimisation of tool path geometry for efficient machining / R.N.Ibrahim, P.K.Kee and A.K.Shrivastava -- Machining of metal matrix composite (AISiC-2618) with carbide cutting tools / Jaharah A.Ghani and Iawaid -- Incestigation of chatter arising in machine tool fixture work system during turning / A.K.M.Nurul Amin and Md.Khaled Khalil -- A machining algorithm for spatial cam surfaces / C.J.Backhouse and J.Rees Jones -- Software development for on-line multi-objective optimization of turning operation / M.K.Khare and J.P.Prasad -- Electrical discharge machinig of cast metal matrix composites /N.P.Hung, L.J.Yang and K.W.Leong -- Surface finish of electro-discharge machined components / K.P.Rajurkar and S.R.Nooka -- Fine profile trueing of metal bonded diamond wheels by EDM on NC profile grinder / T.Uematsu, K.Suzuki, T.Yanase and T.Makizaki -- The electrical discharge machining of 6061 AI/SiCp composites / P.K.Madan and R.Sagar -- Optimal selection of electro-chemical wire cutting process parameters / P.C.Pandey and P.C.Gupta -- Effects of workpiece boundary and motion on laser cutting front phenomena / P.Di Pietro and Y.L.Yao -- A numerical approach for estimating the parameters in dressing grinding wheels with a pulsed laser / V.Phanindranath and N.R.Babu -- Precision machinig of advanced ceramics / S.C.Laroiya and M.Adithan -- Technological developments in near-net-shape casting for mini-steelmills / L.L.Teoh -- A feature based modeling of a welded plate construction / W.K.Dong, T.Kishinami, J.K.Young, K.Saito -- On a model for estimating the interfacial contaminant expelling rate in friction welding of tubular form / Y.P.Lei and Y.W.Shi -- Analysis of residual stresses in hemispherical head to cylindrical shell joints of steam generator by weld cycle simulation / Y.V.L.N. …”

Evaluation of the Antioxidant Properties of Carvacrol as a Prospective Replacement for Crude Essential Oils and Synthetic Antioxidants in Food Storage by Israel Ehizuelen Ebhohimen, Ngozi P. Okolie, Moses Okpeku, Mfon Unweator, Victoria T. Adeleke, Lawrence Edemhanria

“…The IC₅₀ for MCA and NOSA were: carvacrol 50.29 µL/mL, seed essential oil (SEO) 71.06 µL/mL; and carvacrol 127.61 µL/mL, SEO 165.18 µL/mL, respectively. …”
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Expression of truncated chalcone synthase from Boesenbergia rotunda L. mansf. in Escherichia coli by Parmin, Nor Azizah

“…The value of RNA yield for optimization of B. rotunda specific CTAB RNA extraction method was 2.0 μg/g. A reverse transcriptase-polymerase chain reaction (RT-PCR) based approach was used to identify and isolate a partial-length cDNA coding for CHS gene. …”
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Vaccinomics-Aided Development of a Next-Generation Chimeric Vaccine against an Emerging Threat: <i>Mycoplasma genitalium</i> by Kashaf Khalid, Tajamul Hussain, Zubia Jamil, Khalid Salman Alrokayan, Bashir Ahmad, Yasir Waheed

“…In this study, we utilized reverse vaccinology to develop a chimeric vaccine against <i>M. genitalium</i> by identifying vaccine targets from the reference proteome (Strain G-37) of this pathogen. …”
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Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics by Garima Singh, Sri Krishna jayadev Magani, Rinku Sharma, Basharat Bhat, Ashish Shrivastava, Madhusudhan Chinthakindi, Ashutosh Singh

“…Structural mutated models of nsSNP mutants (L26V and S53G) were prepared by MODELLER v9.15 and evaluated using TM-Align, Verify 3D, ProSA and Ramachandran plot. …”
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Design and Synthesis of Various 5′-Deoxy-5′-(4-Substituted-1,2,3-Triazol-1-yl)-Uridine Analogues as Inhibitors of <i>Mycobacterium tuberculosis</i> Mur Ligases by Vincent Hervin, Ritu Arora, Jyoti Rani, Srinivasan Ramchandran, Urmi Bajpai, Luigi A. Agrofoglio, Vincent Roy

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Immunoinformatics-Driven Design of an HPV-16 and -18 Synthetic Long Peptide Vaccine by Alexandru TÎRZIU, Leonard MADA, Corina VERNIC, Virgil PĂUNESCU

“…Molecular docking studies provided a ΔG of −13.20±1.42 kcal/mol, and an average Kd of 3.5×10−9 M. …”
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Production, Characterization And Expression Of An Organic Solvent Tolerant Lipase From Pseudomonas Aeruginosa S5s5 by Baharum, Syarul Nataqain

“…However, the S5 lipase was strongly inhibited by the addition of 1 mM phenyl methyl sulfonyl fluoride (PMSF) (87% inhibition) and 1 rnM of Pepstatin (76% inhibition) after 30 min incubation. …”
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Immunoinformatics Approach to Design Multi-Epitope-Based Vaccine against Machupo Virus Taking Viral Nucleocapsid as a Potential Candidate by Muhammad Naveed, Syeda Izma Makhdoom, Urooj Ali, Khizra Jabeen, Tariq Aziz, Ayaz Ali Khan, Sumbal Jamil, Muhammad Shahzad, Metab Alharbi, Abdulrahman Alshammari

“…The immune simulations demonstrated a long-lasting antibody response even after the excretion of the antigen from the body in the first 5 days of injection. The IgM + IgG titers were predicted to rise to 6000 10 days post-injection and were illustrated to be stable (around 3000) after a month, elucidating that the vaccine would be effective and provide enduring protection. …”
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Development of protease deficient Meyerozyma guilliermondii strain so for overexpression of thermostable T1 lipase by Lorrine, Okojie Eseoghene

“…Next, positive transformants were obtained after 24 h of growth incubation time on a selective medium containing 200 μg/mL of nourseothrincin (NAT). Finally, optimization of recombinant proteins (T1 and T1SLip lipase) expression with the developed mutants in shake flask was carried out using recombinant pPICZαB/T1/APM-(APMSO2), pPICZαB/T1/SPM-(SPMSO2), pPICZαB/T1/DPM-(DPMSO2), pPICZαB/T1SLip/APM-(APM_807), pPICZαB/T1SLip/SPM-(SPM_089) and pPICZαB/T1SLip/DPM-(DPM_0789). …”
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Sequence-structure correlations in the MaSp1 protein of N. clavipes dragline silk by Bratzel, Graham Hayden

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