PET-MR and SPECT-MR multimodality probes: development and challenges by Yang, Chang-Tong, Ghosh, Krishna Kanta, Padmanabhan, Parasuraman, Langer, Oliver, Liu, Jiang, Eng, David Ng Chee, Halldin, Christer, Gulyás, Balázs

“…Due to its advantages over stand-alone PET, SPECT or MR imaging, in many areas such as oncology, the demand for hybrid imaging techniques is increasing dramatically. …”
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Gefitinib and EGFR gene copy number aberrations in esophageal cancer by Petty, RD, Dahle-Smith, A, Stevenson, DAJ, Osborne, A, Massie, D, Clark, C, Murray, GI, Dutton, SJ, Roberts, C, Chong, IY, Mansoor, W, Thompson, J, Harrison, M, Chatterjee, A, Falk, SJ, Elyan, S, Garcia-Alonso, A, Fyfe, DW, Wadsley, J, Chau, I, Ferry, DR, Miedzybrodzka, Z

The generation of Paneth-like cells in colorectal cancer to alter T-cell responses by Ng, ME

“…Immunotherapy in colorectal cancer (CRC), the third most diagnosed cancer worldwide, results in limited and unpredictable responses. There are two main molecular subtypes of CRC: microsatellite unstable and the more common microsatellite stable type. …”

Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells by Alshwyeh, Hussah Abdullah, Al-Sheikh, Warqaa Muhammed Shariff, Rasedee, Abdullah, Alnasser, Sulaiman Mohammed, Al-Qubaisi, Mothanna Sadiq, Ibrahim, Wisam Nabeel

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Engineering periodic short hairpin RNA delivery systems for enhanced therapeutic efficacy by Wu, Connie,Ph. D.Massachusetts Institute of Technology.

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Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression by Rohani, Nazanin, Moufarrej, Mira N., Jones, Joan G., Condeelis, John S., Gertler, Frank B., Oudin, Madeleine Julie, Gertler, Frank, Hughes-Alford, Shannon Kay, Lauffenburger, Douglas A

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Temporally Programmed CD8α[superscrip +] DC Activation Enhances Combination Cancer Immunotherapy by Szeto, Gregory L., Overwijk, Willem W., Tzeng, Alice, Kauke, Monique Jacqueline, Zhu, Eric Franklin, Moynihan, Kelly Dare, Opel, Cary Francis, Yang, Nicole Jie Yeon, Mehta, Naveen, Irvine, Darrell J, Wittrup, Karl Dane

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The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior by Condeelis, John S., Balsamo, Michele, Mondal, Chandrani, Carmona, Guillaume, McClain, Leslie Marie, Riquelme, Daisy Noelia, Tadros, Jenny, Ma, Duanduan, Vasile, Eliza, Lauffenburger, Douglas A, Gertler, Frank

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miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis by Prabhala, Harsha, Mestdagh, Pieter, Muth, Daniel, Teruya-Feldstein, Julie, Westermann, Frank, Speleman, Frank, Vandesompele, Jo, Ma, Li-Jun, Young, Jennifer J, Pan, Elizabeth, Reinhardt, Ferenc, Onder, Tamer T, Valastyan, Scott John, Weinberg, Robert A

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New technologies and methodologies for the study of human mammary epithelial differentiation and development by Miller, Daniel Handel

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Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells by Kröger, Cornelia, Afeyan, Alexander, Mraz, Jasmin, Eaton, Elinor Ng, Reinhardt, Ferenc, Thiru, Prathapan, Bierie, Brian, Ye, Xin, Weinberg, Robert A

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Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice by Hamza, Bashar, Miller, Alex B., Meier, Lara, Stockslager, Max, Ng, Sheng Rong, King, Emily M., Lin, Lin, DeGouveia, Kelsey L., Mulugeta, Nolawit, Calistri, Nicholas L., Strouf, Haley, Bray, Christina, Rodriguez, Felicia, Freed-Pastor, William A., Chin, Christopher R., Jaramillo, Grissel C., Burger, Megan L., Weinberg, Robert A., Shalek, Alex K., Jacks, Tyler, Manalis, Scott R.

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Distinct Hepatic Gene‐Expression Patterns of NAFLD in Patients With Obesity by Subudhi, Sonu, Drescher, Hannah K, Dichtel, Laura E, Bartsch, Lea M, Chung, Raymond T, Hutter, Matthew M, Gee, Denise W, Meireles, Ozanan R, Witkowski, Elan R, Gelrud, Louis, Masia, Ricard, Osganian, Stephanie A, Gustafson, Jenna L, Rwema, Steve, Bredella, Miriam A, Bhatia, Sangeeta N, Warren, Andrew, Miller, Karen K, Lauer, Georg M, Corey, Kathleen E

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The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain by Stern, Patrick, Liu, Hui, Schindler, Jeffrey W., Jiang, Zhigang, Lamar, John, Hynes, Richard O

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Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy by Pallasch, Christian, Leskov, Ilya B., Vorholt, Daniela, Drake, Adam, Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina P., Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Braun, Christian Joerg, Soto Feliciano, Yadira Marie, Hemann, Michael

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Multiple neoplasia in a patient with Gitelman syndrome harboring germline monoallelic MUTYH mutation by Chan, Jason Yongsheng, Toh, Ming Ren, Chong, Siao Ting, Nur Diana Ishak, Kolinjivadi, Arun Mouli, Chan, Sock Hoai, Lee, Elizabeth, Boot, Arnoud, Shao-Tzu, Li, Chew, Min-Hoe, Ngeow, Joanne

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Small molecules targeting the inactive form of the Mnk1/2 kinases by Kannan, Srinivasaraghavan, Pradhan, Mohan R., Cherian, Joseph, Joseph, Thomas L., Poh, Zhi Ying, Hai Yan, Yang, Melvyn, Ho, Boping, Liu, Jeffrey, Hill, Nacro, Kassoum, Verma, Chandra Shekhar

“…Here, we describe computational models of the interactions between Mnk1/2 kinases and these inhibitors. Molecular modeling combined with free energy calculations show that these compounds bind to the inactive forms of the kinases. …”
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Susceptibility of Human Oral Squamous Cell Carcinoma (OSCC) H103 and H376 cell lines to Retroviral OSKM mediated reprogramming by Verusingam, Nalini Devi, Yeap, Swee Keong, Ky, Huynh, Paterson, Ian Charles, Khoo, Suan Phaik, Cheong, Soon Keng, Ong, Alan H.K., Kamarul, Tunku

“…Subjects Cell Biology, Molecular Biology, Oncology, Medical Genetics.…”

Synergistic Growth Inhibition by Afatinib and Trametinib in Preclinical Oral Squamous Cell Carcinoma Models by Yee, Pei San, Zainal, Nur Syafinaz, Gan, Chai Phei, Lee, Bernard K.B., Mun, Kein Seong, Abraham, Mannil Thomas, Ismail, Siti Mazlipah, Rahman, Zainal Ariff Abdul, Patel, Vyomesh, Cheong, Sok Ching

Immunohistochemical localization of hTERT protein in oral carcinogenesis by Kumar, S., Ismail, S.M., Zain, R.B., Abraham, M.T., Cheong, S.C.

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