Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM) by Norman, J, Marlow, N, Messow, C, Shennan, A, Bennett, P, Thornton, S, Robson, S, McConnachie, A, Petrou, S, Sebire, N, Lavender, T, Whyte, S, Norrie, J

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Progressive exercise compared with best-practice advice, with or without corticosteroid injection, for rotator cuff disorders: the GRASP factorial RCT by Hopewell, S, Keene, DJ, Heine, P, Marian, IR, Dritsaki, M, Cureton, L, Dutton, SJ, Dakin, H, Carr, A, Hamilton, W, Hansen, Z, Jaggi, A, Littlewood, C, Barker, K, Gray, A, Lamb, SE

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Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT by Thwaites, GE, Scarborough, M, Szubert, AJ, Concalves, P, Soares, M, Bostock, J, Nsutebu, E, Tilley, R, Cunningham, R, Grieg, J, Wyllie, SA, Wilson, P, Auckland, C, Cairns, J, Ward, D, Lal, P, Guleri, A, Jenkins, N, Sutton, J, Wiselka, M, Armando, G-R, Graham, C, Chadwick, PR, Barlow, G, Gordon, C, Young, B, Meisner, S, McWhinney, P, Price, DA, Harvey, D, Nayar, D, Jeyaratnam, D, Planche, T, Minton, J, Hudson, F, Hopkins, S, Williams, J, Torok, EM, Llewelyn, MJ, Edgeworth, JD, Walker, AS

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Amisulpride for very late-onset schizophrenia-like psychosis: the ATLAS three-arm RCT by Howard, R, Cort, E, Bradley, R, Harper, E, Kelly, L, Bentham, P, Ritchie, C, Reeves, S, Fawzi, W, Livingston, G, Sommerlad, A, Oomman, S, Nazir, E, Nilforooshan, R, Barber, R, Fox, C, Macharouthu, A, Ramachandra, P, Pattan, V, Sykes, J, Curran, V, Katona, C, Dening, T, Knapp, M, Romeo, R, Gray, R

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Enhanced psychological care in cardiac rehabilitation services for patients with new-onset depression: the CADENCE feasibility study and pilot RCT by Richards, S, Campbell, J, Dickens, C, Anderson, R, Gandhi, M, Gibson, A, Kessler, D, Knight, L, Kuyken, W, Richards, D, Taylor, R, Turner, K, Ukoumunne, O, Davey, A, Warren, F, Winder, R, Wright, C

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Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT. by Perkins, G, Mistry, D, Lall, R, Gao-Smith, F, Snelson, C, Hart, N, Camporota, L, Varley, J, Carle, C, Paramasivam, E, Hoddell, B, De Paeztron, A, Dosanjh, S, Sampson, J, Blair, L, Couper, K, McAuley, D, Young, J, Walsh, T, Blackwood, B, Rose, L, Lamb, S, Dritsaki, M, Maredza, M, Khan, I, Petrou, S, Gates, S

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Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT. by Costa, M, Achten, J, Hennings, S, Boota, N, Griffin, J, Petrou, S, Maredza, M, Dritsaki, M, Wood, T, Masters, J, Pallister, I, Lamb, S, Parsons, N

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Clinical effectiveness and cost-effectiveness of a multifaceted podiatry intervention for falls prevention in older people: a multicentre cohort randomised controlled trial (the RE... by Cockayne, S, Rodgers, S, Green, L, Fairhurst, C, Adamson, J, Scantlebury, A, Corbacho, B, Hewitt, C, Hicks, K, Hull, R, Keenan, A, Lamb, S, McIntosh, C, Menz, H, Redmond, A, Richardson, Z, Vernon, W, Watson, J, Torgerson, D

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A video-feedback parenting intervention to prevent enduring behaviour problems in at-risk children aged 12-36 months: the Healthy Start, Happy Start RCT by O'Farrelly, C, Barker, B, Watt, H, Babalis, D, Bakermans-Kranenburg, M, Byford, S, Ganguli, P, Grimås, E, Iles, J, Mattock, H, McGinley, J, Phillips, C, Ryan, R, Scott, S, Smith, J, Stein, A, Stevens, E, van IJzendoorn, M, Warwick, J, Ramchandani, P

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Treatment of first-time traumatic anterior shoulder dislocation: the UK TASH-D cohort study by Rees, J, Shah, A, Edwards, K, Sanchez-Santos, M, Robinson, D, Delmestri, A, Carr, A, Arden, N, Lamb, S, Rangan, A, Judge, A, Pinedo-Villanueva, R, Holt, T, Hopewell, S, Prieto Alhambra, D, Collins, G

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Intravenous co-amoxiclav to prevent infection after operative vaginal delivery: the ANODE RCT by Knight, M, Chiocchia, V, Partlett, C, Rivero-Arias, O, Hua, X, Bowler, U, Gray, J, Gray, S, Hinshaw, K, Khunda, A, Moore, P, Mottram, L, Owino, N, Pasupathy, D, Sanders, J, Sultan, A, Thakar, R, Tuffnell, D, Linsell, L, Juszczak, E

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Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment - systematic review and model... by Farmer, A, Stevens, R, Hirst, J, al., E

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Prospective multicentre randomised, double-blind, equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety... by Wolf, A, McKay, A, Spowart, C, Granville, H, Boland, A, Petrou, S, Sutherland, A, Gamble, C

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Cognitive therapy compared with CBT for social anxiety disorder in adolescents: a feasibility study by Creswell, C, Leigh, E, Larkin, M, Stephens, G, Violato, M, Brooks, E, Pearcey, S, Taylor, L, Stallard, P, Waite, P, Reynolds, S, Taylor, G, Warnock-Parkes, E, Clark, DM

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Randomised controlled trial evaluating the effectiveness and cost-effectiveness of 'Families for Health', a family-based childhood obesity treatment intervention delivered in a com... by Robertson, W, Fleming, J, Kamal, A, Hamborg, T, Khan, K, Griffiths, F, Stewart-Brown, S, Stallard, N, Petrou, S, Simkiss, D, Harrison, E, Kim, S, Thorogood, M

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Computerised interpretation of the fetal heart rate during labour: a randomised controlled trial (INFANT) by Brocklehurst, P, Field, D, Greene, K, Juszczak, E, Kenyon, S, Linsell, L, Mabey, C, Newburn, M, Plachcinski, R, Quigley, M, Steer, P, Schroeder, L, Rivero-Arias, O

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A multicentre, randomised controlled trial of position during the late stages of labour in nulliparous women with an epidural: clinical effectiveness and an economic evaluation (BU... by Bick, D, Briley, A, Brocklehurst, P, Hardy, P, Juszczak, E, Lynch, L, MacArthur, C, Moore, P, Nolan, M, Rivero-Arias, O, Sanders, J, Shennan, A, Wilson, M

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Bisphosphonates to reduce bone fractures in stage 3B+ chronic kidney disease: a propensity score-matched cohort study by Robinson, DE, Ali, MS, Strauss, VY, Elhussein, L, Abrahamsen, B, Arden, NK, Ben-Shlomo, Y, Caskey, F, Cooper, C, Dedman, C, Delmestri, A, Judge, A, Javaid, M, Prieto-Alhambra, D

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Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT by Beard, DJ, Davies, LJ, Cook, JA, MacLennan, G, Price, A, Kent, S, Hudson, J, Carr, A, Leal, J, Campbell, H, Fitzpatrick, R, Arden, N, Murray, D, Campbell, MK, TOPKAT Study Group

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Patch Augmented Rotator Cuff Surgery (PARCS) feasibility study by Cook, J, Baldwin, M, Cooper, C, Nagra, N, Crocker, J, Glaze, M, Greenall, G, Rangan, A, Kottam, L, Rees, J, Farrar-Hockley, D, Merritt, N, Hopewell, S, Beard, D, Thomas, M, Dritsaki, M, Carr, A

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