Essays on markets and information by Gitmez, Ahmet Arda.

Get full text

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity by Régnier, Marion, Polizzi, Arnaud, Smati, Sarra, Lukowicz, Céline, Fougerat, Anne, Lippi, Yannick, Fouché, Edwin, Lasserre, Frédéric, Naylies, Claire, Bétoulières, Colette, Barquissau, Valentin, Mouisel, Etienne, Bertrand-Michel, Justine, Batut, Aurélie, Saati, Talal Al, Canlet, Cécile, Tremblay-Franco, Marie, Ellero-Simatos, Sandrine, Langin, Dominique, Postic, Catherine, Wahli, Walter, Loiseau, Nicolas, Guillou, Hervé, Montagner, Alexandra

“…Peroxisome proliferator activated receptor α (PPARα) acts as a fatty acid sensor to orchestrate the transcription of genes coding for rate-limiting enzymes required for lipid oxidation in hepatocytes. …”
Get full text

Blessings or burdens : an interpretative phenomenological analysis (IPA) study on the motivations and their impact on end-of-life caregiving among Asian family caregivers by Tan-Ho, Geraldine, Choo, Ping Ying, Patinadan, Paul Victor, Low, Casuarine Xinyi, Ho, Andy Hau Yan

Get full text

Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention by Khoo, Bee Luan, Grenci, Gianluca, Lim, Joey Sze Yun, Lim, Yan Ping, Fong, July, Yeap, Wei Hseun, Lim, Su Bin, Chua, Song Lin, Wong, Siew Cheng, Yap, Yoon-Sim, Lee, Soo Chin, Lim, Chwee Teck, Han, Jongyoon

“…The response of patients varied due to clinical heterogeneity, with 62.5% and 64.7% of samples demonstrating higher killing efficacy or reduction in cancer stem cell (CSC) proportions after DA treatment, respectively. …”
Get full text

A non-viral genome editing platform for site-specific insertion of large transgenes by Chaudhari, Namrata, Rickard, Amanda M., Roy, Suki, Dröge, Peter, Makhija, Harshyaa

Get full text

DNA methylation and lipid metabolism : an EWAS of 226 metabolic measures by Gomez-Alonso, Monica del C., Kretschmer, Anja, Wilson, Rory, Pfeiffer, Liliane, Karhunen, Ville, Seppälä, Ilkka, Zhang, Weihua, Mittelstraß, Kirstin, Wahl, Simone, Matias-Garcia, Pamela R., Prokisch, Holger, Horn, Sacha, Meitinger, Thomas, Serrano-Garcia, Luis R., Sebert, Sylvain, Raitakari, Olli, Loh, Marie, Rathmann, Wolfgang, Müller-Nurasyid, Martina, Herder, Christian, Roden, Michael, Hurme, Mikko, Jarvelin, Marjo-Riitta, Ala-Korpela, Mika, Kooner, Jaspal S., Peters, Annette, Lehtimäki, Terho, Chambers, John Campbell, Gieger, Christian, Kettunen, Johannes, Waldenberger, Melanie

“…Identified metabolic measures were primarily medium and small lipoproteins, and fatty acids. For apolipoprotein B-containing lipoproteins, the associations mainly involved triglyceride composition and concentrations of cholesterol esters, triglycerides, free cholesterol, and phospholipids. …”
Get full text

A feedforward loop within the thyroid-brown fat axis facilitates thermoregulation by Sun, Lijuan, Goh, Hui Jen, Govindharajulu, Priya, Sun, Lei, Henry, Christiani Jeyakumar, Leow, Melvin Khee-Shing

Get full text

The prevalence of lower eyelid epiblepharon and its association with refractive errors in Chinese preschool children : a cross-sectional study by Zhuo, Deyi, Chen, Si, Ren, Xiaofang, Wang, Bingsong, Liu, Linbo, Xiao, Lin

Get full text

Measuring upper limb function and patient reported outcomes after major breast cancer surgery : a pilot study in an Asian cohort by Chan, Kai Siang, Zeng, Ding, Leung, Joelle Hoi Ting, Ooi, Belinda Si Yin, Kong, Kit Teng, Yeo, Yi Heng, Goo, Jerry Tiong Thye, Chia, Clement Luck Khng

“…Baseline demographics and peri-operative data were also collected. Results: Median age was 62.5 years. …”
Get full text

Development and validation of the Rapid Positive Mental Health Instrument (R-PMHI) for measuring mental health outcomes in the population by Vaingankar, Janhavi Ajit, Abdin, Edimansyah, van Dam, Robertus Martinus, Chong, Siow Ann, Tan, Linda Wei Lin, Sambasivam, Rajeswari, Seow, Esmond, Chua, Boon Yiang, Wee, Hwee Lin, Lim, Wei Yen, Subramaniam, Mythily

Get full text

Stratified primary care versus non-stratified care for musculoskeletal pain : qualitative findings from the STarT MSK feasibility and pilot cluster randomized controlled trial by Saunders, Benjamin, Hill, Jonathan C., Foster, Nadine E., Cooper, Vince, Protheroe, Joanne, Chudyk, Adrian, Chew-Graham, Carolyn, Bartlam, Bernadette

Get full text

Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice by Ivan, Fransiskus Xaverius, Kwoh, Chee Keong

“…Many individual studies have been carried out in mice to uncover the viral factors responsible for the virulence of IAV infections. …”
Get full text

Collaborative model of care between Orthopaedics and allied healthcare professionals in knee osteoarthritis (CONNACT) : study protocol for an effectiveness-implementation hybrid ra... by Tan, Bryan Yijia, Pereira, Michelle Jessica, Yang, Su-Yin, Hunter, David J., Skou, Soren Thorgaard, Thumboo, Julian, Car, Josip

Get full text

Individual-fMRI-approaches reveal cerebellum and visual communities to be functionally connected in obsessive compulsive disorder by Kashyap, Rajan, Eng, Goi Khia, Bhattacharjee, Sagarika, Gupta, Bhanu, Ho, Roger, Ho, Cyrus S. H., Zhang, Melvyn, Mahendran, Rathi, Sim, Kang, Chen, Annabel Shen-Hsing

Get full text

Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery by Chun, Yong Yao, Yap, Zhu Li, Seet, Li Fong, Chan, Hiok Hong, Toh, Li Zhen, Chu, Stephanie W. L., Lee, Ying Shi, Wong, Tina T., Tan, Timothy Thatt Yang

Get full text

Hierarchical discovery of large-scale and focal copy number alterations in low-coverage cancer genomes by Ahmed Ibrahim Samir Khalil, Khyriem, Costerwell, Chattopadhyay, Anupam, Sanyal, Amartya

“…We implemented Savitzky-Golay smoothing filter and Modified Varri segmentation to capture the change points of the RD signal. …”
Get full text

Using cluster analysis to reconstruct dengue exposure patterns from cross-sectional serological studies in Singapore by Sangkaew, Sorawat, Tan, Li Kiang, Ng, Lee Ching, Ferguson, Neil M., Dorigatti, Ilaria

“…Methods: We explored the use of five distinct clustering methods (i.e. agglomerative hierarchical, divisive hierarchi-cal, K-means, K-medoids and model-based clustering) with varying number (from 4 to 10) of clusters for each method. …”
Get full text

Altered striatal dopamine levels in Parkinson's disease VPS35 D620N mutant transgenic aged mice by Vanan, Sarivin, Zeng, Xiaoxia, Chia, Sook Yoong, Varnäs, Katarina, Jiang, Mei, Zhang, Ke, Saw, Wuan Ting, Padmanabhan, Parasuraman, Yu, Wei-Ping, Zhou, Zhi-Dong, Halldin, Christer, Gulyás, Balázs, Tan, Eng-King, Zeng, Li

“…Lastly, autoradiography (ARG) evaluation of [3H]FE-PE2I binding to the striatal dopamine transporter DAT was carried out. We found that VPS35 D620N Tg mice displayed a significantly higher dopamine level than NTg counterparts. …”
Get full text

Chirality-assisted lateral momentum transfer for bidirectional enantioselective separation by Shi, Yuzhi, Zhu, Tongtong, Zhang, Tianhang, Mazzulla, Alfredo, Tsai, Din Ping, Ding, Weiqiang, Liu, Ai Qun, Cipparrone, Gabriella, Sáenz, Juan José, Qiu, Cheng-Wei

Get full text

System-wide molecular dynamics of endothelial dysfunction in Gram-negative sepsis by Gallart-Palau, Xavier, Serra, Aida, Sze, Siu Kwan

Get full text