Smokeless and combustible tobacco use among 148,944 South Asian adults: a cross-sectional study of South Asia Biobank by Xie, Wubin, Mridha, Malay Kanti, Gupta, Anaya, Kusuma, Dian, Butt, Awais Muhammad, Hasan, Mehedi, Brage, Soren, Loh, Marie, Khawaja, Khadija Irfan, Pradeepa, Rajendra, Jha, Vinita, Kasturiratne, Anuradhani, Katulanda, Prasad, Anjana, Ranjit Mohan, Chambers, John Campbell

“…Conclusions: In this large population-based study of South Asian adults, rates of smoking and SLT use vary widely by country and gender. Men who use SLT products are more likely to abstain from smoking compared with those who do not.…”
Get full text

Platform for the interdisciplinary study of cardiovascular, metabolic and neurovascular diseases (PICMAN) protocol by Dalakoti, Mayank, Leow, Melvin Khee Shing, Khoo, Chin Meng, Yang, Hayang, Ling, Lieng Hsi, Muthiah, Mark, Tan, Eunice, Lee, Jonathan, Dan, Yock Young, Chew, Nicholas, Seow, Wei Qiang, Soong, Poh Loong, Gan, Louis, Gurung, Rijan, Ackers-Johnson, Matthew, Hou, Han Wei, Sachaphibulkij, Karishma, MacAry, Paul, Low, Gwen, Ang, Christy, Yeo, Tee Joo, Djohan, Andie Hartanto, Li, Tony, Yeung, Wesley, Soh, Rodney, Sia, Ching Hui, Panday, Vinay, Loong, Shaun S. E., Tan, Benjamin Y. Q., Yeo, Leonard L. L., Teo, Lynette, Chow, Pierce, Foo, Roger

“…Participants aged 21-72 years with no prior manifest atherosclerotic cardiovascular disease (ASCVD) are being recruited from a preventive cardiology clinic and an existing cohort of non-alcoholic fatty liver disease (NAFLD) in an academic medical centre. …”
Get full text

TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase by Liu, Gang, Haw, Tatt Jhong, Starkey, Malcolm R., Philp, Ashleigh M., Pavlidis, Stelios, Nalkurthi, Christina, Nair, Prema M., Gomez, Henry M., Hanish, Irwan, Hsu, Alan Cy, Hortle, Elinor, Pickles, Sophie, Rojas-Quintero, Joselyn, Estepar, Raul San Jose, Marshall, Jacqueline E., Kim, Richard Y., Collison, Adam M., Mattes, Joerg, Idrees, Sobia, Faiz, Alen, Hansbro, Nicole G., Fukui, Ryutaro, Murakami, Yusuke, Cheng, Hong Sheng, Tan, Nguan Soon, Chotirmall, Sanjay Haresh, Horvat, Jay C., Foster, Paul S., Oliver, Brian Gg, Polverino, Francesca, Ieni, Antonio, Monaco, Francesco, Caramori, Gaetano, Sohal, Sukhwinder S., Bracke, Ken R., Wark, Peter A., Adcock, Ian M., Miyake, Kensuke, Sin, Don D., Hansbro, Philip M.

Get full text

How do older adults with multimorbidity navigate healthcare?: a qualitative study in Singapore by Lee, Sabrina Poay Sian, Chew, Evelyn Ai Ling, Koh, Hui Li, Quak, Stephanie Xin En, Ding, Yew Yoong, Subramaniam, Mythily, Vaingankar, Janhavi Ajit, Lee, Eng Sing

Get full text

Impact of interventions on the quality of life of cancer patients: a systematic review and meta-analysis of longitudinal research by Nguyen, Long Bao, Vu, Linh Gia, Le, Thanh Thien, Nguyen, Xuan Thanh, Dao, Nam Gia, Nguyen, Duy Cao, Dang, Trang Huyen Thi, Vu, Thuc Minh Thi, Boyer, Laurent, Fond, Guillaume, Auquier, Pascal, Latkin, Carl A., Zhang, Melvyn, Ho, Roger C. M., Ho, Cyrus S. H.

Get full text

Carbene organic catalytic planar enantioselective macrolactonization by Lv, Xiaokang, Su, Fen, Long, Hongyan, Lu, Fengfei, Zeng, Yukun, Liao, Minghong, Che, Fengrui, Wu, Xingxing, Chi, Robin Yonggui

“…Our strategy utilizes N-heterocyclic carbene (NHC) as a potent acylation catalyst that simultaneously mediates the macrocyclization and controls planar chirality during the catalytic process. Macrolactones varying in ring sizes from sixteen to twenty members are obtained with good-to-excellent yields and enantiomeric ratios. …”
Get full text

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma by Chuah, You Heng, Tay, Emmy Xue Yun, Grinchuk, Oleg V., Yoon, Jeehyun, Feng, Jia, Kannan, Srinivasaraghavan, Robert, Matius, Jakhar, Rekha, Liang, Yajing, Lee, Bernice Woon Li, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M., Lu, Guang, Low, Boon Chuan, Crasta, Karen Carmelina, Verma, Chandra Shekhar, Lin, Zhewang, Ong, Derrick Sek Tong

Get full text

Spin-related Cu-Co pair to increase electrochemical ammonia generation on high-entropy oxides by Sun, Shengnan, Dai, Chencheng, Zhao, Peng, Xi, Shibo, Ren, Yi, Tan, Hui Ru, Lim, Poh Chong, Lin, Ming, Diao, Caozheng, Zhang, Danwei, Wu, Chao, Yu, Anke, Koh, Jackson Jie Cheng, Lieu, Wei Ying, Seng, Debbie Hwee Leng, Sun, Libo, Li, Yuke, Tan, Teck Leong, Zhang, Jia, Xu, Jason Zhichuan, Seh, Zhi Wei

“…By correlating the electronic structure, we found that the Co spin states are crucial for the Cu-Co synergistic effect for ammonia generation. The Cu-Co pair with a high spin Co in Mg0.2Co0.2Ni0.2Cu0.2Zn0.2O can facilitate ammonia generation, while a low spin Co in Li-incorporated MgCoNiCuZnO decreases the Cu-Co synergistic effect on ammonia generation. …”
Get full text

Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing by Pranantyo, Dicky, Yeo, Chun Kiat, Wu, Yang, Fan, Chen, Xu, Xiaofei, Yip, Yun Sheng, Vos, Marcus Ivan Gerard, Mahadevegowda, Surendra H., Lim, Priscilla Lay Keng, Yang, Liang, Hammond, Paula T., Leavesley, David Ian, Tan, Nguan Soon, Chan-Park, Mary B.

Get full text

Synergistic-potential engineering enables high-efficiency graphene photodetectors for near- to mid-infrared light by Jiang, Hao, Fu, Jintao, Wei, Jingxuan, Li, Shaojuan, Nie, Changbin, Sun, Feiying, Wu, Steve Qing Yang, Liu, Mingxiu, Dong, Zhaogang, Wei, Xingzhan, Gao, Weibo, Qiu, Cheng-Wei

“…High quantum efficiency and wide-band detection capability are the major thrusts of infrared sensing technology. However, bulk materials with high efficiency have consistently encountered challenges in integration and operational complexity. …”
Get full text

Prevalence and correlates of depressive symptoms among matriculated university students in Singapore during Covid-19 pandemic: findings from a repeated cross-sectional analysis by Yeo, Pearlie Mei En, Qin, Vicky Mengqi, Ang, Chin-Siang, Chia, Michael, Ho, Ringo Moon-Ho, Ho, Andy Hau Yan, Car, Josip

Get full text

The role of perfusion, grey matter volume and behavioural phenotypes in the data-driven classification of cognitive syndromes by Vipin, Ashwati, Lee, Bernett Teck Kwong, Kumar, Dilip, Soo, See Ann, Leow, Yi Jin, Ghildiyal, Smriti, Lee, Faith Phemie Hui En, Hilal, Saima, Kandiah, Nagaendran

Get full text

Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma by Liu, Min, Bertolazzi, Giorgio, Sridhar, Shruti, Lee, Rui Xue, Jaynes, Patrick, Mulder, Kevin, Syn, Nicholas, Hoppe, Michal Marek, Fan, Shuangyi, Peng, Yanfen, Thng, Jocelyn, Chua, Reiya, Jayalakshmi, Batumalai, Yogeshini, De Mel, Sanjay, Poon, Limei, Chan, Esther Hian Li, Lee, Joanne, Hue, Susan Swee-Shan, Chang, Sheng-Tsung, Chuang, Shih-Sung, Chandy, Kanianthara George, Ye, Xiaofei, Pan-Hammarström, Qiang, Ginhoux, Florent, Chee, Yen Lin, Ng, Siok-Bian, Tripodo, Claudio, Jeyasekharan, Anand D.

“…Macrophage estimation by immunohistochemistry shows varying prognostic significance across studies in DLBCL, and does not provide a comprehensive analysis of macrophage subtypes. …”
Get full text

LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase by Zeng, Judeng, Xie, Chuan, Huang, Ziheng, Cho, Chi H., Chan, Hung, Li, Qing, Ashktorab, Hassan, Smoot, Duane T., Wong, Sunny Hei, Yu, Jun, Gong, Wei, Liang, Cong, Xu, Hongzhi, Chen, Huarong, Liu, Xiaodong, Wu, Justin C. Y., Ip, Margaret, Gin, Tony, Zhang, Lin, Chan, Matthew T. V., Hu, Wei, Wu, William K. K.

Get full text

Predicting cognitive scores from wearable-based digital physiological features using machine learning: data from a clinical trial in mild cognitive impairment by Rykov, Yuri G., Patterson, Michael D., Gangwar, Bikram A., Jabar, Syaheed B., Leonardo, Jacklyn, Ng, Kok Pin, Kandiah, Nagaendran

Get full text

Association of plasma angiogenin with risk of major cardiovascular events in type 2 diabetes by Gurung, Resham L., Liu, Sylvia, Liu, Jian-Jun, Yiamunaa, M., Zheng, Huili, Chan, Clara, Ang, Keven, Subramaniam, Tavintharan, Sum, Chee Fang, Lim, Su Chi

Get full text

Crosstalk between CD64+MHCII+ macrophages and CD4+ T cells drives joint pathology during chikungunya by Lum, Fok-Moon, Chan, Yi-Hao, Teo, Teck-Hui, Becht, Etienne, Amrun, Siti Naqiah, Teng, Karen W. W., Hartimath, Siddesh V., Yeo, Nicholas K. W., Yee, Wearn-Xin, Ang, Nicholas, Torres-Ruesta, Anthony M., Fong, Siew-Wai, Goggi, Julian L., Newell, Evan W., Renia, Laurent, Carissimo, Guillaume, Ng, Lisa F. P.

Get full text

Late Holocene relative sea-level records from coral microatolls in Singapore by Tan, Fangyi, Horton, Benjamin Peter, Ke, Lin, Li, Tanghua, Quye-Sawyer, Jennifer, Lim, Joanne T. Y., Peng, Dongju, Aw, Zihan, Wee, Shi Jun, Yeo, Jing Ying, Haigh, Ivan, Wang, Xianfeng, Aung, Lin Thu, Mitchell, Andrew, Sarkawi, Gina, Li, Xinnan, Tan, Nurul Syafiqah, Meltzner, Aron J.

Get full text

BANKSY unifies cell typing and tissue domain segmentation for scalable spatial omics data analysis by Singhal, Vipul, Chou, Nigel, Lee, Joseph, Yue, Yifei, Liu, Jinyue, Chock, Wan Kee, Lin, Li, Chang, Yun-Ching, Teo, Erica Mei Ling, Aow, Jonathan, Lee, Hwee Kuan, Chen, Kok Hao, Prabhakar, Shyam

Get full text

A method for mining condition-specific co-expressed genes in Camellia sinensis based on k-means clustering by Zheng, Xinghai, Lim, Peng Ken, Mutwil, Marek, Wang, Yuefei

“…This approach proved instrumental in identifying a series of high CDV transcription factor encoding genes upregulated during sustained cold treatment in Camellia sinensis leaves and buds, and pinpointing a pair of genes that participate in the antioxidant defense system of tea plants under sustained cold stress. …”
Get full text