Published 2022-05-01
“…Laura Ceriotti,1 Paolo Buratti,1 Enrico Stefano Corazziari,2 Marisa Meloni1 1In vitro Innovation
Center, VitroScreen srl, Milan, Italy; 2Department of Gastroenterology, IRCCS Humanitas
Research Hospital, Rozzano (Milan), ItalyCorrespondence: Laura Ceriotti, VitroScreen, in vitro Innovation
Center, Via Mosè Bianchi, 103, Milan, 20149, Italy, Email laura.ceriotti@vitroscreen.comPurpose: A novel experimental design based on a human-reconstructed oesophageal epithelium (HO2E) model has been applied to quantitively assess the
properties of a set of liquid formulations, Device A (Gerdoff® Protection), Device B (Esoxx® One), and Device C (Marial® gel) developed to form a temporary physical barrier on the oesophageal epithelium and modify epithelial permeability so to protect the oesophageal mucosa from refluxate components.Methods: The formulations were applied to a prewetted HO2E model for 15 min. …”
Get full text
Article