Auditory Rehabilitation in Rhesus Macaque Monkeys (Macaca mulatta) with Auditory Brainstem Implants by Zhen-Min Wang, Zhi-Jun Yang, Fu Zhao, Bo Wang, Xing-Chao Wang, Pei-Ran Qu, Pi-Nan Liu

“…This study aimed to establish an animal model of ABI in adult rhesus macaque monkey (Macaca mulatta). Methods: Six adult rhesus macaque monkeys (M. mulatta) were included. …”
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Phenotypes and genetic etiology of spontaneous polycystic kidney and liver disease in cynomolgus monkey by Ruo Wu, Ruo Wu, Bing Bai, Bing Bai, Feng Li, Raoxian Bai, Raoxian Bai, Yan Zhuo, Yan Zhuo, Zhengna Zhu, Zhengna Zhu, Rongfang Jia, Rongfang Jia, Shangang Li, Shangang Li, Yongchang Chen, Yongchang Chen, Xiaoping Lan

“…IntroductionPolycystic kidney disease (PKD) is a common autosomal dominant or recessive genetic disease, often accompanied by polycystic liver disease (PLD). …”
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Characteristics of Spontaneous Square-Wave Jerks in the Healthy Macaque Monkey during Visual Fixation. by Francisco M Costela, Jorge Otero-Millan, Michael B McCamy, Stephen L Macknik, Leandro L Di Stasi, Héctor Rieiro, John R Leigh, Xoana G Troncoso, Ali Najafian Jazi, Susana Martinez-Conde

“…SWJs are present in most human subjects, but are prominent by their increased frequency and size in certain parkinsonian disorders and in recessive, hereditary spinocerebellar ataxias. SWJs have been also documented in monkeys with tectal and cerebellar etiologies, but no studies to date have investigated the occurrence of SWJs in healthy nonhuman primates. …”
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A novel nonsense mutation in the tyrosinase gene is related to the albinism in a capuchin monkey (Sapajus apella) by Felipe Tadeu Galante Rocha de Vasconcelos, Einat Hauzman, Leonardo Dutra Henriques, Paulo Roney Kilpp Goulart, Olavo de Faria Galvão, Ronaldo Yuiti Sano, Givago da Silva Souza, Jessica Lynch Alfaro, Luis Carlos de Lima Silveira, Dora Fix Ventura, Daniela Maria Oliveira Bonci

“…Abstract Background Oculocutaneous Albinism (OCA) is an autosomal recessive inherited condition that affects the pigmentation of eyes, hair and skin. …”
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The Progress in Treatment of β-Thalassemia and Research on Animal Models of the Disease by Shumeng Zhang, Zexia Dong, Wenhao Yan, Wenjing Wang, Yangli Pei, Zheng Feng

“…β-thalassemia is one of the most prevalent single-gene recessive disorders worldwide, characterized by the impaired synthesis of β-globin chains, which leads to ineffective erythropoiesis and results in anemia and iron overload, along with various complications. …”
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5meCpG epigenetic marks neighboring a primate-conserved core promoter short tandem repeat indicate X-chromosome inactivation. by Filipe Brum Machado, Fabricio Brum Machado, Milena Amendro Faria, Viviane Lamim Lovatel, Antonio Francisco Alves da Silva, Claudia Pamela Radic, Carlos Daniel De Brasi, Álvaro Fabricio Lopes Rios, Susana Marina Chuva de Sousa Lopes, Leonardo Serafim da Silveira, Carlos Ramon Ruiz-Miranda, Ester Silveira Ramos, Enrique Medina-Acosta

“…We conducted the RP2 onshore tandem GAAA repeat assay in the naturally occurring chimeric New World monkey marmoset (Callitrichidae) and found it to be informative. …”
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A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy by Chicoine Louis G, Coley Brian D, Montgomery Chrystal L, Janssen Paul ML, Rodino-Klapac Louise R, Clark K Reed, Mendell Jerry R

“…<p>Abstract</p> <p>Background</p> <p>Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder with monogenic mutations setting the stage for successful gene therapy treatment. …”
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Clinical, Genetic and Orthopedic Characteristics of Desbuquois Dysplasia by Tatyana V. Markova, Vladimir M. Kenis, Evgeniy V. Melchenko, Peter A. Sparber, Marina S. Petukhova, Igor O. Bychkov, Tatyana S. Nagornova, Olga L. Shatokhina, Elena L. Dadali

“…Desbuquois dysplasia is a rare skeletal dysplasia with an autosomal recessive inheritance, resembling to the group of multiple joint dislocations. …”
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Preclinical studies in support of phase I/II clinical trials to treat GUCY2D-associated Leber congenital amaurosis by Sanford L. Boye, Catherine O’Riordan, James Morris, Michael Lukason, David Compton, Rena Baek, Dana M. Elmore, James.J. Peterson, Diego Fajardo, K. Tyler McCullough, Abraham Scaria, Alison McVie-Wylie, Shannon E. Boye

“…Dose-ranging studies were conducted in cynomolgus monkeys to establish the minimum dose required for efficient photoreceptor transduction. …”
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AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice by Vivian W Choi, Chad E Bigelow, Terri L McGee, Akshata N Gujar, Hui Li, Shawn M Hanks, Joanna Vrouvlianis, Michael Maker, Barrett Leehy, Yiqin Zhang, Jorge Aranda, George Bounoutas, John T Demirs, Junzheng Yang, Richard Ornberg, Yu Wang, Wendy Martin, Kelly R Stout, Gregory Argentieri, Paul Grosenstein, Danielle Diaz, Oliver Turner, Bruce D Jaffee, Seshidhar R Police, Thaddeus P Dryja

“…Recessive mutations in RLBP1 cause a form of retinitis pigmentosa in which the retina, before its degeneration leads to blindness, abnormally slowly recovers sensitivity after exposure to light. …”
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Environmental and economical ethics collide by Camille Castelyn

“…The world has entered into a recession, with estimates of a US $2 trillion loss. …”
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