Analysis of Tospovirus NSs Proteins in Suppression of Systemic Silencing. by Marcio Hedil, Mark G Sterken, Dryas de Ronde, Dick Lohuis, Richard Kormelink

“…Using the system established, a set of selected NSsTSWV gene constructs mutated in predicted RNA binding domains, as well as NSs from TSWV isolates 160 and 171 (resistance breakers of the Tsw resistance gene), were analyzed for their ability to suppress systemic GFP silencing. …”
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The role of ArlRS in regulating oxacillin susceptibility in methicillin-resistant Staphylococcus aureus indicates it is a potential target for antimicrobial resistance breakers by Jinna Bai, Xiaoyi Zhu, Keqing Zhao, Yingjie Yan, Tao Xu, Jiaxue Wang, Jinxing Zheng, Wei Huang, Le Shi, Yongpeng Shang, Zhihui Lv, Xiaofei Wang, Yang Wu, Di Qu

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Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels by Sophia Schedin-Weiss, Mitsuhiro Inoue, Lenka Hromadkova, Yasuhiro Teranishi, Natsuko Goto Yamamoto, Birgitta Wiehager, Nenad Bogdanovic, Bengt Winblad, Anna Sandebring-Matton, Susanne Frykman, Lars O. Tjernberg

“…Potentially, the γ-secretase/MAO-B association may be a target for reducing Aβ levels using protein–protein interaction breakers.…”
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Suppression of a Prolyl 4 Hydroxylase Results in Delayed Abscission of Overripe Tomato Fruits by Andreas Perrakis, Craita E. Bita, Stilianos Arhondakis, Afrodite Krokida, Khansa Mekkaoui, Dusan Denic, Konstantinos N. Blazakis, Dimitrios Kaloudas, Panagiotis Kalaitzis

“…Moreover, structural changes were observed in the silenced SlP4H3AZs. The fracture plane of the AZ was curved and not along a line as in wild type and there was a lack of lignin deposition in the AZs of overripe fruits 30 days after breaker. …”
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Effects of Endogenous Melatonin Deficiency on the Growth, Productivity, and Fruit Quality Properties of Tomato Plants by Zhuo He, Cen Wen, Wen Xu

“…In this experiment, tomato plants (<i>slcomt1</i>) with silenced <i>SlCOMT1</i> gene expression were used to investigate the effects of <i>SlCOMT1</i> deficiency on fruit growth, development, and quality formation. …”
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Role of peroxisome proliferators-activated receptor-gamma in advanced glycation end product-mediated functional loss of voltage-gated potassium channel in rat coronary arteries by Side Gao, Bing Hua, Qingbo Liu, Huirong Liu, Weiping Li, Hongwei Li

“…Methods The RSCAs and primary CSMCs were isolated, cultured, and treated with bovine serum albumin (BSA), AGE-BSA, alagrebrium (ALA, AGE cross-linking breaker), pioglitazone (PIO, PPAR-γ activator) and/or GW9662 (PPAR-γ inhibitor). …”
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