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    Bioactivity Profiling and Untargeted Metabolomics of Microbiota Associated with Mesopelagic Jellyfish <i>Periphylla periphylla</i> by Ernest Oppong-Danquah, Martina Miranda, Martina Blümel, Deniz Tasdemir

    Published 2023-02-01
    “…The marine mesopelagic zone extends from water depths of 200 m to 1000 m and is home to a vast number and diversity of species. …”
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    Semi-Synthesis, Cytotoxic Evaluation, and Structure—Activity Relationships of Brefeldin A Derivatives with Antileukemia Activity by Xu-Xiu Lu, Yao-Yao Jiang, Yan-Wei Wu, Guang-Ying Chen, Chang-Lun Shao, Yu-Cheng Gu, Ming Liu, Mei-Yan Wei

    Published 2021-12-01
    “…Brefeldin A (<b>1</b>), a potent cytotoxic natural macrolactone, was produced by the marine fungus <i>Penicillium</i> sp. (HS-N-29) from the medicinal mangrove <i>Acanthus ilicifolius</i>. …”
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    Anti-Quorum-Sensing Activity of Tryptophan-Containing Cyclic Dipeptides by Yinglu Wang, Qian Zheng, Li Li, Lile Pan, Hu Zhu

    Published 2022-01-01
    “…</i><i>violaceum</i> CV026 and predicted as binding within the same pocket of receptor protein CviR, but in lower binding energy compared with the natural ligand C<sub>6</sub>HSL. As for <i>P. aeruginosa</i> PAO1, owning more complicated QS systems, these CDPs also exhibited inhibitory effects on pyocyanin production, swimming motility, biofilm formation, and adhesion. …”
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    Antiproliferative and Antimicrobial Potentials of a Lectin from <i>Aplysia kurodai</i> (Sea Hare) Eggs by Rubaiya Rafique Swarna, A. K. M. Asaduzzaman, Syed Rashel Kabir, Nawshin Arfin, Sarkar M. A. Kawsar, Sultana Rajia, Yuki Fujii, Yukiko Ogawa, Keisuke Hirashima, Nanae Kobayashi, Masao Yamada, Yasuhiro Ozeki, Imtiaj Hasan

    Published 2021-07-01
    “…The lectin was shown to be moderately toxic to brine shrimp nauplii, with an LC<sub>50</sub> value of 63.63 µg/mL. It agglutinated Ehrlich ascites carcinoma cells and reduced their growth, up to 58.3% in vivo when injected into Swiss albino mice at a rate of 2 mg/kg/day. …”
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    Antifreeze Peptides and Glycopeptides, and Their Derivatives: Potential Uses in Biotechnology by Hyun-Cheol Kim, Hak Jun Kim, Hye Yeon Koh, Hye-Eun Shim, Hackwon Do, Sung Gu Lee, Ravichandran N. Murugan, Jun Hyuck Lee, Jeong Kyu Bang

    Published 2013-06-01
    “…These compounds possess the ability to inhibit the formation of ice and are therefore essential to the survival of many marine teleost fishes that routinely encounter sub-zero temperatures. …”
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  12. 332

    Comparative Evaluation of the Antibacterial and Antitumor Activities of 9-Phenylfascaplysin and Its Analogs by Maxim E. Zhidkov, Maria A. Sidorova, Polina A. Smirnova, Oleg A. Tryapkin, Andrey V. Kachanov, Alexey V. Kantemirov, Lyubov G. Dezhenkova, Natalia E. Grammatikova, Elena B. Isakova, Andrey E. Shchekotikhin, Marina A. Pak, Olga N. Styshova, Anna A. Klimovich, Aleksandr M. Popov

    Published 2024-01-01
    “…Based on the results of our own preliminary studies, the derivative of the marine alkaloid fascaplysin containing a phenyl substituent at C-9 was selected to evaluate the therapeutic potential in vivo and in vitro. …”
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    Synergistic Anti-<em>Candida</em> Activity of Bengazole A in the Presence of Bengamide A by Matthew T. Jamison, Xiao Wang, Tina Cheng, Tadeusz F. Molinski

    Published 2019-02-01
    “…The MOA of bengazole A was further explored by monitoring the sterol composition of <i>C. albicans</i> in the presence of sub-lethal concentrations of bengazole A. …”
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