Integrating tacrolimus into eutectic oil-based microemulsion for atopic dermatitis: simultaneously enhancing percutaneous delivery and treatment efficacy with relieving side effect... by Wang Y, Cao S, Yu K, Yang F, Yu X, Zhai Y, Wu C, Xu Y

“…Moreover, they can form a liquid eutectic oil to solubilize hydrophobic drugs.Purpose: Taking advantages of menthol/camphor eutectic (MCE), this work aims to integrate FK506 into MCE to construct a microemulsion system, i.e., FK506 MCE ME, which simultaneously enhances the percutaneous delivery and treatment efficacy, while reduces the side effects of FK506.Methods: The formulation of FK506 MCE ME was optimized and characterized. …”
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Magnetocentrifugal Mechanism of Pair Creation in AGN by Zaza N. Osmanov, Gianluigi Bodo, Paola Rossi

“…Researchers have studied this process across a wide range of AGN luminosities and black hole masses, and found that the mechanism is highly efficient, indicating that for AGNs where centrifugal effects are significant, the annihilation lines in the MeV range will be very strong.…”
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The Free Tricoordinated Silyl Cation Problem by Čičak, H.

“…As the importance and abundance of silicon in our environment is large, it has been thought that silicon might take the place of carbon in forming a host of similar compounds and silicon-based life. …”
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Nano based lutein extraction from marigold petals: optimization using different surfactants and co-surfactants by Mehdi Jalali Jivan, Soliman Abbasi

“…The present study endeavored to take advantage of nanotech approach (i.e microemulsion, ME), as a novel green technique, for lutein extraction from marigold (Tagetes erecta) as an industrial crop. …”
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Editorial by Christian Gütl

“…It gives me great pleasure to announce the eighth regular issue of 2022. …”
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The Farewell Sermon: An Analytical Rhetorical Study by jalil Fleah

“…Karim is rich in his sublime meanings and sound contents, formulated in eloquent style and accurate performance, so the goal is to stand at passages of this prophetic text which is the farewell sermon, full of its rhetorical connotations to reveal the aesthetics of employing rhetorical art that is contained in the prophetic hadith away from the suffering of workmanship and insertion or seeking the verbal sweetness that There is no singing in it and what made me take on this conch - rather the difficult complex - that I do not find great attention to texts and a celebration of analyzing their formulas and syntheses, and showing the precise locations of art and rhetorical methods distinct from their presence in the words of other people, so that readers stand on a color of study that is at the time The same is an implicit balance for employing the arts of rhetoric with capabilities that go above and beyond what amounts to a miracle, and a depravity that predicts the representation of a verbal form and a verbal emptiness and an intellectual emptiness. …”
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Diagnosing major depression in medical outpatients: acceptability of telephone interviews. by Allen, K, Cull, A, Sharpe, M

“…Ninety-four percent of all questionnaire respondents and 84% (n=31) of those who reported the interview to have been distressing endorsed the item "Had I known in advance what answering the questions would have been like for me, I would still have agreed to take part". Perceiving the interview as distressing was associated with having major depression (P<.001). …”

An Introduction and Mission of Building Bridges to Reach the Unknown by James Houran

“…But my primary aim is now to take the journal to the next level by bolstering its familiarity, reach, and influence within academia and the mainstream consciousness alike. …”
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Off-equatorial effects of the nonlinear interaction of VLF chorus waves with radiation belt electrons by John C. Foster, Philip J. Erickson

“…We examine the important dependencies of the nonlinear inhomogeneity factor on the time rate of change of the wave frequency and the field-aligned gradient of the magnetic field and discuss their implication for the energization of trapped non-relativistic and MeV electrons. The 0.5–2% energy gain we find for 3–6 MeV seed electrons indicates that prompt local acceleration of highly relativistic and ultra-relativistic radiation belt electrons can take place directly through their nonlinear interaction with an individual VLF chorus wave element.…”
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Conservation through community: An attempt to untangle a tangled word. by Deeraj Koul

“…Conservation is not something that can be thrust upon a community, and neither can it be labelled as a measure to take away a people’s rights and nor can it be used as a force to make others adhere to rules and laws from outside; by outside I mean you and me and your or my Government. …”
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An interview with Steven J. Lindauer by Steven J. Lindauer

“…And needless to say at length about his brilliance ahead of “The Angle Orthodontist”... It didn’t take me long to realize that his virtues by far exceeded the boundaries of the professional domain. …”
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A paradigmatic dialogue-disagreement in a democratic school: A conceptual analysis of a soul-searching assembly meeting by Ana Marjanovic-Shane

“…The EGO students’ intensive and urgent ontological need to explain their very different positions to each other allowed me to take a closer look into the tensions and conflicts still existing in the larger cultural-historical public sphere of discourse on education. …”
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Sharing Marks: H3K4 Methylation and H2B Ubiquitination as Features of Meiotic Recombination and Transcription by Joan Serrano-Quílez, Sergi Roig-Soucase, Susana Rodríguez-Navarro

“…Both the formation of programmed meiotic DNA double-strand breaks (DSBs) and their repair using homologous chromosomes are essential and highly regulated pathways. Similar to other processes that take place in the context of chromatin, histone posttranslational modifications (PTMs) constitute one of the major mechanisms to regulate meiotic recombination. …”
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The Paramecium histone chaperone Spt16-1 is required for Pgm endonuclease function in programmed genome rearrangements. by Augustin de Vanssay, Amandine Touzeau, Olivier Arnaiz, Andrea Frapporti, Jamie Phipps, Sandra Duharcourt

“…Normal accumulation of 25 nt scanRNAs and deposition of silent histone marks H3K9me3 and H3K27me3 indicated that Spt16-1 does not regulate the scanRNA-directed heterochromatin pathway involved in the early steps of DNA elimination. …”
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Monetary efficiency in the dynamic public cloud environments by Chen, Changbing

“…In particular, we conduct detailed study on improving the mon- etary efficiency by leveraging spot instances. We take a cloud broker’s perspective to propose a price-aware virtual machine auto-scaling with migration algorithm, called MaxME, to improve Hadoop’s monetary efficiency on Amazon EC2. …”
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Magnetoelectric Magnetic Field Sensors: A Review by Mirza Bichurin, Roman Petrov, Oleg Sokolov, Viktor Leontiev, Viktor Kuts, Dmitry Kiselev, Yaojin Wang

“…Taking into account the high sensitivity of ME magnetic field sensors, comparable to superconducting quantum interference devices (SQUIDs), we discuss the areas of their application.…”
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Introduction of Research Work on Laser Proton Acceleration and Its Application Carried out on Compact Laser–Plasma Accelerator at Peking University by Dongyu Li, Tang Yang, Minjian Wu, Zhusong Mei, Kedong Wang, Chunyang Lu, Yanying Zhao, Wenjun Ma, Kun Zhu, Yixing Geng, Gen Yang, Chijie Xiao, Jiaer Chen, Chen Lin, Toshiki Tajima, Xueqing Yan

“…Laser plasma acceleration has made remarkable progress in the last few decades, but it also faces many challenges. Although the high gradient is a great potential advantage, the beam quality of the laser accelerator has a certain gap, or it is different from that of traditional accelerators. …”
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Medication Errors in Secondary Care Hospitals in Kuwait: The Perspectives of Healthcare Professionals by Fatemah M. Alsaleh, Sara Alsaeed, Zahra K. Alsairafi, Noor B. Almandil, Abdallah Y. Naser, Tania Bayoud

“…Most HCPs (n = 129, 62.0%) reported that the most common type of ME is “prescribing error,” followed by “compliance error” (n = 83; 39.9%). …”
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“I wanted to know what was hurting so much”: a qualitative study exploring patients’ expectations and experiences with primary care management by Véronique Lowry, François Desmeules, Diana Zidarov, Patrick Lavigne, Jean-Sébastien Roy, Audrey-Anne Cormier, Yannick Tousignant-Laflamme, Kadija Perreault, Marie-Claude Lefèbvre, Simon Décary, Anne Hudon

“…Four overarching themes related to patients’ expectations and experiences were identified from our thematic analysis: 1) I can’t sleep because of my shoulder; 2) I need to know what is happening with my shoulder; 3) But… we need to really see what is going on to help me!; and 4) Please take some time with me so I can understand what to do!. …”
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Interview with Arthur Caplan by Kaitlynd Hiller, Rachel F Bloom

“…It takes a lot to get me to really jump down somebody’s throat in an angry way, but I’m trying to say, you know, we can argue about these things.  …”
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